1-17 of 17
Keywords: stress response
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2022) 479 (13): 1467–1486.
Published: 12 July 2022
... Correspondence: Peter J. Parker ( peter.parker@crick.ac.uk ) or Angela Clerk ( a.clerk@reading.ac.uk ) cardiac development cardiomyopathy Protein kinase N stress response References 1 Bouma , B.J. and Mulder , B.J. ( 2017 ) Changing landscape of congenital heart disease...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2022) 479 (10): 1059–1082.
Published: 23 May 2022
... is catalysed by any one of four protein kinases, which are generally activated in response to stresses. They form a key arm of the integrated stress response (ISR). Phosphorylated eIF2 inhibits eIF2B (the protein that promotes exchange of eIF2-bound GDP for GTP) and thus impairs general protein synthesis...
Articles
Biochem J (2020) 477 (15): 2755–2770.
Published: 07 August 2020
... syndrome and cancer. Correspondence: Frank McCormick ( Frank.mccormick@ucsf.edu ) 27 5 2020 1 7 2020 2 7 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 cancer GTPases point mutations stress response...
Articles
Biochem J (2014) 461 (3): 509–520.
Published: 10 July 2014
... the lysosomal compartment to expand. However, the molecular and cellular mechanisms for this stress response remain largely unclear. In the present study, we find that short-term fasting leads to increased accumulation of polar lipids in lysosomes. The fasting response is co-ordinately regulated by EGL-4, the C...
Includes: Supplementary data
Articles
Biochem J (2013) 453 (3): 381–391.
Published: 12 July 2013
... in cellular metabolism and various stress responses. 1 Present address: Cardiac Hypertrophy Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, VIC 3004, Australia 2 To whom correspondence should be addressed (email marieb@unimelb.edu.au ). 10 12 2012 17 5 2013 22 5...
Includes: Supplementary data
Articles
Biochem J (2012) 441 (1): 119–129.
Published: 14 December 2011
... protein (eIF4E-inhibitory protein) processing body stress granule stress response Cells have evolved multiple strategies to cope with environmental insults, such as oxidative, genotoxic, hyperosmotic and heat shock, and viral infection. The cellular response to these stresses involves a global...
Includes: Supplementary data
Articles
Biochem J (2010) 429 (3): 403–417.
Published: 14 July 2010
... regulation mitogen-activated protein kinase (MAPK) p38 phosphorylation signalling stress response Cells need to be constantly aware of changes in the extracellular milieu to respond accordingly, so they have developed sophisticated mechanisms to receive signals, transmit the information...
Articles
Biochem J (2007) 401 (2): 559–567.
Published: 21 December 2006
... response Cellular responses to extracellular stress signals play an important role in the maintenance of homoeostasis under adverse conditions. An early stress response is to activate cascades of phosphorylation events that, in many cases, increase the expression of the immediate early genes...
Articles
Biochem J (2006) 400 (2): 235–244.
Published: 14 November 2006
... regulation of SGK-1 steady-state levels alters SGK-1 kinase activity. These data suggest a model that integrates CHIP function with regulation of the PI3K/SGK-1 pathway in the stress response. 1 To whom correspondence should be addressed ( sconzen@medicine.bsd.uchicago.edu ). 15 6 2006 24 7...
Articles
Biochem J (2006) 393 (1): 201–209.
Published: 12 December 2005
..., as well as the UPR (unfolded protein response) in mammalian cells. To delineate the regulatory machinery underlying PERK-dependent stress-responses, gene profiling was employed to assess global changes in gene expression in PERK-deficient MEFs (mouse embryonic fibroblasts). Several IE (immediate-early...
Articles
Biochem J (2005) 392 (1): 145–152.
Published: 08 November 2005
... factor 1 (HSF1) heat-shock protein 70 (Hsp70) stress response Various physiological and cellular stresses can disrupt essential cellular signalling pathways and inhibit protein synthesis leading to dramatic increases in the levels of unfolded proteins, disruption of the cytoskeleton and loss...
Articles
Biochem J (2005) 385 (2): 371–380.
Published: 07 January 2005
...Hao-Yuan JIANG; Ronald C. WEK In response to UV irradiation, mammalian cells elicit a gene expression programme designed to repair damage and control cell proliferation and apoptosis. Important members of this stress response include the NF-κB (nuclear factor-κB) family. However, the mechanisms...
Articles
Biochem J (2005) 385 (1): 255–264.
Published: 14 December 2004
... 9 2004 9 9 2004 The Biochemical Society, London 2005 bacterial signal transduction membrane receptor NMR osmolarity stress response E. coli strain BL21(DE3) was used for expression of pET15b-EnvZ per . Cells were grown to exponential phase in 2 litres of LB (Luria...
Includes: Supplementary data
Articles
Biochem J (2002) 361 (2): 371–377.
Published: 08 January 2002
...Julie A. MORAN; Erica L. DAHL; R. Timothy MULCAHY The three small Maf proteins, MafF, MafG and MafK, have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Here we report the constitutive expression of mafF , mafG...
Articles
Biochem J (2000) 352 (3): 795–800.
Published: 08 December 2000
... were induced by heat shock. methyl methanesulphonate stress response yeast two-hybrid system Biochem. J. (2000) 352, 795 800 (Printed in Great Britain) 795 Interaction between DNA-damage protein GADD34 and a new member of the Hsp40 family of heat shock proteins that is induced by a DNA...
Articles
Biochem J (1999) 339 (3): 729–736.
Published: 26 April 1999
... of ONOO - . 1 To whom correspondence should be addressed (e-mail r.foresti@ic.ac.uk). 24 6 1998 21 1 1999 17 2 1999 The Biochemical Society, London © 1999 1999 bilirubin HSP32 stress response tin protoporphyrin IX Biochem. J. (1999) 339, 729 736 (Printed in Great...
Articles
Biochem J (1999) 339 (1): 135–141.
Published: 25 March 1999
... transactivation and arsenite-induced activation of the Gadd153 promoter. Our results suggest that numerous members of the ATF/CREB family are involved in the cellular stress response, and that regulation of stress-induced biphasic Gadd153 expression in PC12 cells involves the ordered, sequential binding...