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Keywords: steroids
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Articles
Biochem J (2018) 475 (1): 75–85.
Published: 02 January 2018
...Anna M. Barron; Bin Ji; Seiji Kito; Tetsuya Suhara; Makoto Higuchi The translocator protein (TSPO) has been proposed to act as a key component in a complex important for mitochondrial cholesterol importation, which is the rate-limiting step in steroid hormone synthesis. However, TSPO function...
Articles
Articles
Biochem J (2016) 473 (2): 107–121.
Published: 05 January 2016
... with high affinity synthetic and endogenous ligands, its core biochemical function resides in the translocation of cholesterol into the mitochondria influencing the subsequent steps of (neuro-)steroid synthesis and systemic endocrine regulation. Over the years, however, TSPO has also been linked to core...