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Keywords: spermidine synthase
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Biochem J (2011) 438 (2): 229–244.
Published: 12 August 2011
... is considered. α-difluoromethylornithine Leishmania malaria ornithine decarboxylase (ODC) polyamine S -adenosylmethionine decarboxylase (AdoMetDC) spermidine synthase Trypanosoma Both of the human aminopropyltransferases SpdS and SpmS exist as dimers of two identical subunits. Neither...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2008) 409 (2): 563–569.
Published: 21 December 2007
... to treat patients with late-stage African trypanosomiasis, the requirement for additional drug targets is paramount. Here, we report the biochemical properties of TbSpSyn ( Trypanosoma brucei spermidine synthase), the enzyme immediately downstream of ODC in this pathway. Recombinant TbSpSyn was purified...