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Keywords: sepsis
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Biochem J (2022) 479 (6): 731–750.
Published: 28 March 2022
...Tristram A. J. Ryan; Roger J. S. Preston; Luke A. J. O'Neill The interplay between innate immunity and coagulation after infection or injury, termed immunothrombosis, is the primary cause of disseminated intravascular coagulation (DIC), a condition that occurs in sepsis. Thrombosis associated...
Biochem J (2013) 450 (2): 265–274.
Published: 15 February 2013
... The Authors Journal compilation © 2013 Biochemical Society 2013 Alzheimer’s disease heart failure Parkinson’s disease sepsis synaptic vesicle vascular dementia Cholinergic neurons in the CNS (central nervous system) and in the periphery secrete the neurotransmitter ACh (acetylcholine...
Includes: Multimedia, Supplementary data
Biochem J (2012) 443 (2): 355–359.
Published: 27 March 2012
... caspase 11 inhibitor of apoptosis protein (IAP) lipopolysaccharide (LPS) sepsis ES (embryonic stem) cell lines from the murine 129 strain are frequently used to derive genetically modified mice [ 1 ]. A recent report examining the role of caspase 1 in an endotoxin-induced murine model of sepsis...
Biochem J (2011) 436 (1): 123–132.
Published: 27 April 2011
...Damon A. Lowes; Helen F. Galley Oxidative stress and mitochondrial dysfunction are common features in patients with sepsis and organ failure. Within mitochondria, superoxide is converted into hydrogen peroxide by MnSOD (manganese-containing superoxide dismutase), which is then detoxified by either...
Includes: Supplementary data
Biochem J (2006) 394 (2): 519–526.
Published: 10 February 2006
... verified by restriction digests, and inserts were sequenced with appropriate vector-specific and gene-specific primers. acute-phase response albumin glutathione S-transferase (GST) hepatic nuclear factor 1 (HNF1) sepsis ubiquitin-specific protease 3 (USP3) The acute-phase response...
Biochem J (2004) 382 (2): 471–479.
Published: 24 August 2004
... for unpaired data. diabetes gluconeogenesis glucose-6-phosphatase insulin liver sepsis G6Pase (glucose-6-phosphatase) catalyses the final step of the metabolic pathways that are central to hepatic glucose production, i.e. gluconeogenesis and glycogen breakdown [ 1 ]. Thus G6Pase has...
Biochem J (2004) 377 (3): 763–768.
Published: 01 February 2004
... to increased IL6DEX-NP binding. IL6DEX-NP appears to be an important negative regulator of gene expression in vitro and in vivo . cytokine gene regulation sepsis transcription transcription factor Abbreviations used: DEX, dexamethasone; EMSA, electrophoretic mobility-shift assay; GST...
Biochem J (2003) 370 (1): 315–321.
Published: 15 February 2003
...Kumudika I. de SILVA; Asif N. DAUD; JiangPing DENG; Stephen B. JONES; Richard L. GAMELLI; Ravi SHANKAR Interleukin-6 (IL-6), a potent myeloid mitogen, and the immunosuppressive prostanoid prostaglandin E 2 (PGE 2 ) are elevated following thermal injury and sepsis. We have previously demonstrated...
Biochem J (2002) 366 (2): 399–404.
Published: 01 September 2002
..., London ©2002 2002 peroxynitrite sepsis tyrosine nitration Abbreviations used: COPD, chronic obstructive pulmonary disease; hr, human recombinant; IFN-γ, interferon-γ; LPS, lipopolysaccharide; MALDI-TOF MS, matrix-assisted laser-desorption ionization–time-of-flight MS; Mn-SOD, manganese...
Biochem J (2002) 366 (1): 97–107.
Published: 15 August 2002
... 2002 neurodegenerative nitrosative stress oxidative stress peroxynitrite sepsis Abbreviations used: C-PTIO, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline 1-oxyl 3-oxide; DTPA, diethylenetriaminepenta-acetic acid; IFN-γ, interferon-γ; LPS, lipopolysaccharide; Mn-Salen, manganese...
Biochem J (2001) 360 (1): 143–150.
Published: 08 November 2001
...Christiane DEVAL; Sylvie MORDIER; Christiane OBLED; Daniel BECHET; Lydie COMBARET; Didier ATTAIX; Marc FERRARA Alteration of skeletal muscle protein breakdown is a hallmark of a set of pathologies, including sepsis, with negative consequences for recovery. The aim of the present study was to search...
Biochem J (2001) 353 (2): 325–331.
Published: 08 January 2001
... and progression of periodontitis. 1 To whom correspondence should be addressed (e-mail taka@kaiju.medic.kumamoto-u.ac.jp ). 12 6 2000 3 10 2000 6 11 2000 The Biochemical Society, London © 2001 2001 pathogenesis periodontitis proteolysis sepsis zymogen activation Biochem...