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Ribosomal protein S19-binding domain provides insights into hantavirus nucleocapsid protein-mediated translation initiation mechanism

Safder S. Ganaie, Absarul Haque, Erdong Cheng, Tania S. Bonny, Nilshad N. Salim, Mohammad A. Mir
Journal: Biochemical Journal
Biochem J (2014) 464 (1): 109–121.
DOI: https://doi.org/10.1042/BJ20140449
Published: 23 October 2014
... protein) augments mRNA translation. N binds to both the mRNA 5′ cap and 40S ribosomal subunit via RPS19 (ribosomal protein S19). N with the assistance of the viral mRNA 5′-UTR preferentially favours the translation of a downstream ORF. We identified and characterized the RPS19-binding domain at the N...
View article titled, <span class="search-highlight">Ribosomal</span> <span class="search-highlight">protein</span> <span class="search-highlight">S19</span>-binding domain provides insights into hantavirus nucleocapsid protein-mediated translation initiation mechanism
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Includes: Supplementary data