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Keywords: reactive oxygen species (ROS)
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Biochem J (2015) 468 (2): 325–336.
Published: 22 May 2015
... and induced autophagy. The potential pro-autophagic activity of Gsdma3 was suppressed through an intramolecular inhibition mechanism between N- and C-terminus. And this mechanism was conserved in Gasdermin family. autophagy Gasdermin A3 GSDM family reactive oxygen species (ROS...
Includes: Supplementary data
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Biochem J (2015) 466 (2): 369–378.
Published: 20 February 2015
... oxidoreductin 1-α (ERO1α), a target of CHOP, is an important oxidizing enzyme that regulates reactive oxygen species (ROS), which play a prominent role in hepatocellular death during acute liver failure (ALF). However, little is known about how CHOP facilitates ROS-induced hepatocellular injury. The present...
Includes: Supplementary data
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Biochem J (2014) 464 (1): 157–168.
Published: 23 October 2014
... (SIRT3) reactive oxygen species (ROS) mitochondrial antioxidant enzyme The oxygen supply to cells or tissues is reduced during aging and in many pathological conditions, including cancer, diabetic retinopathy and cardiovascular diseases [ 1 ]. Low oxygen supply results in hypoxic stress...
Includes: Supplementary data
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Biochem J (2014) 463 (1): 53–63.
Published: 08 September 2014
...Tatsuro Kawamura; Yasumitsu Kondoh; Makoto Muroi; Makoto Kawatani; Hiroyuki Osada Induction of excessive levels of reactive oxygen species (ROS) by small-molecule compounds has been considered a potentially effective therapeutic strategy against cancer cells, which are often subjected to chronic...
Includes: Supplementary data
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Biochem J (2014) 462 (3): 475–487.
Published: 22 August 2014
.... It has been proposed to inhibit respiratory complex I. We show how metformin and related compounds affect both complex I and ATP synthase in mammalian mitochondria. ATP synthase biguanide complex I metformin NADH:quinone oxidoreductase reactive oxygen species (ROS) Metformin...
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Biochem J (2014) 462 (2): 337–345.
Published: 07 August 2014
... expression NADPH oxidase Pichia pastoris post-translational modification protein–protein interaction reactive oxygen species (ROS) The NADPH oxidase complex generates ROS (reactive oxygen species) by transferring electrons from NADPH across biological membranes to dioxygen. These reactions...
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Biochem J (2014) 461 (2): 189–203.
Published: 26 June 2014
... stress-response protein because its expression was increased upon stress and its knockout attenuated virulence of the parasite. chaperone DJ-1/PfpI malaria peroxiredoxin Plasmodium reactive oxygen species (ROS) 1 To whom correspondence should be addressed (email psijwali...
Includes: Supplementary data
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Biochem J (2014) 459 (2): 251–263.
Published: 28 March 2014
... in neuroprotection against apoptosis via HO-1 (haem oxygenase 1) expression in cerebellar granule neurons. neuronal nitric oxide synthase (nNOS) neuroprotection 8-nitro-cGMP phosphorylation redox signalling reactive oxygen species (ROS) In the nervous system, NO is involved in multiple...
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Biochem J (2013) 456 (3): 337–346.
Published: 22 November 2013
... hypoxia-induced cellular responses. hypoxia hypoxia-inducible factor (HIF) hypoxic pulmonary vasoconstriction peroxiredoxin-5 reactive oxygen species (ROS) redox-sensitive GFP (roGFP) Adaptation to low levels of oxygen (hypoxia) is critical for survival, as all multicellular organisms...
Includes: Supplementary data
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Biochem J (2013) 454 (2): 201–208.
Published: 09 August 2013
... to demonstrate ROS involvement in drug-induced apoptosis. catalase Forkhead box protein M1 (FOXM1) N -acetyl- L -cysteine (NAC) reactive oxygen species (ROS) proteasome inhibitor 1 To whom correspondence should be addressed (email agartel@uic.edu ). 21 2 2013 15 6 2013 18 6...
Includes: Supplementary data
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Biochem J (2012) 447 (3): 381–391.
Published: 05 October 2012
... with glutaraldehyde and by native gel electrophoresis, as described in [ 21 ]. Deinococcus radiodurans DNA protection during starvation (Dps) ferroxidase activity green fluorescent protein (GFP) nucleoid organization reactive oxygen species (ROS) Members of the bacterial family Deinococcaceae...
Includes: Supplementary data
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Biochem J (2012) 447 (2): 281–289.
Published: 26 September 2012
... Src tyrosine kinase reactive oxygen species (ROS) Mitochondrial serine/threonine phosphorylation has been investigated in terms of the mitochondrial compartments in which it occurs, and the results of the mitochondrial serine/threonine phosphoproteome have previously been reported [ 1 – 3...
Includes: Supplementary data
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Biochem J (2012) 446 (1): 23–36.
Published: 27 July 2012
... is properly cited. activin receptor type II B autophagy–lysosome system myostatin nuclear factor κB (NF-κB) reactive oxygen species (ROS) skeletal muscle wasting tumoral factor ubiquitin–proteasome system An ELISA (Immuno Diagnostik) was performed according to the manufacturer's...
Includes: Supplementary data
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Biochem J (2012) 445 (3): 441–448.
Published: 13 July 2012
... of cellular ROS levels. 8 2 2012 27 4 2012 15 5 2012 15 5 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 apoptosis cell stress Mg 2+ reactive oxygen species (ROS) transient receptor potential melastatin 7 (TRPM7) Several investigations have...
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Biochem J (2012) 443 (1): 75–84.
Published: 14 March 2012
... PCR as described above. apoptosis lipocalin neuroprotection prostaglandin D synthase reactive oxygen species (ROS) SH-SY5Y Cells were lysed in RIPA buffer containing 50 mM Tris/HCl (pH 8.0), 150 mM NaCl, 0.1% SDS, 0.5% sodium deoxycholate, 1% (v/v) Nonidet P40 and 1% (v/v) Triton X...
Includes: Supplementary data
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Biochem J (2011) 438 (3): 433–436.
Published: 26 August 2011
... regulation immune cell nitric oxide (NO) prostaglandin E 2 reactive oxygen species (ROS) Inflammation is an immune response to infection, tissue injury and other noxious insults [ 1 ]. It is characterized by the production of inflammatory mediators such as cytokines, PGE 2 (prostaglandin E 2...
Includes: Supplementary data
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Biochem J (2011) 435 (3): 545–551.
Published: 13 April 2011
...) mitochondrion reactive oxygen species (ROS) The role of mitochondria in programmed cell death has been studied extensively over the last few decades. It is now well established that stress signals induce changes in mitochondrial membrane permeability, resulting in the release of cytochrome c from...
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Biochem J (2011) 435 (2): 489–498.
Published: 29 March 2011
... step. 1 To whom correspondence should be addressed (email yijing@shsmu.edu.cn ). 14 9 2010 24 1 2011 3 2 2011 3 2 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 promoter analysis reactive oxygen species (ROS) small ubiquitin-related...
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Biochem J (2010) 428 (2): 183–190.
Published: 13 May 2010
... stress reactive oxygen species (ROS) transition metal The molecular mechanisms behind AMD (age-related macular degeneration) are much debated but far from understood, even though it is the most common cause of visual impairment among the elderly in the Western world [ 1 – 3 ]. However...
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Biochem J (2009) 424 (3): 491–500.
Published: 10 December 2009
... and physiological stimuli [ 4 – 7 ]. Compartmentation of selected redox couple changes may further the specificity in the redox control of signal transduction. cysteine nuclear factor-erythroid 2-related factor 2 (Nrf2) reactive oxygen species (ROS) redox thiol thioredoxin © The Authors Journal...
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Biochem J (2009) 423 (1): 109–118.
Published: 14 September 2009
... dmcbado@ucl.ac.uk ). 9 2 2009 14 7 2009 17 7 2009 17 7 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 inositol pyrophosphate inositol hexakisphosphate kinase (IP6K) Kcs1 metabolism Rad53 reactive oxygen species (ROS) Inositol...
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Biochem J (2009) 418 (3): 595–604.
Published: 25 February 2009
... Biochemical Society 2009 apoptosis membrane attack complex (MAC) oxidative phosphorylation reactive oxygen species (ROS) Trypanosoma cruzi trypanosomatid Trypanosoma cruzi is a protozoan parasite of the order Kinetoplastida that causes Chagas' disease, an infection that affects several...
Includes: Supplementary data
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Biochem J (2009) 417 (1): 1–13.
Published: 12 December 2008
..., mitochondrial ROS may act as a modulatable redox signal, reversibly affecting the activity of a range of functions in the mitochondria, cytosol and nucleus. complex I hydrogen peroxide mitochondrion reactive oxygen species (ROS) respiratory chain superoxide Within mitochondria, O 2...
Includes: Multimedia, Supplementary data
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Biochem J (2008) 414 (1): 53–61.
Published: 29 July 2008
..., U.S.A. 4  To whom correspondence should be addressed (email uwe.ludewig@zmbp.uni-tuebingen.de ). aquaglyceroporins aquaporin hydrogen peroxide reactive oxygen species (ROS) 1 2 2008 6 5 2008 8 5 2008 8 5 2008 © The Authors Journal compilation © 2008...
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Biochem J (2008) 413 (3): 389–404.
Published: 15 July 2008
... actin apoptosis mitochondrion programmed cell death (PCD) reactive oxygen species (ROS) The fact that cells are selectively executed during normal development has been recognized and revisited a number of times over the last century [ 1 ]. However, it was not until the recent discovery...
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Biochem J (2008) 413 (1): 1–13.
Published: 12 June 2008
...@leeds.ac.uk . 4 2 2008 22 4 2008 22 4 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 chaperone mitochondrion Parkinson's disease reactive oxygen species (ROS) ubiquitin Parkinson's disease (PD) is the second most common neurodegenerative disease...
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Biochem J (2007) 406 (1): 105–114.
Published: 26 July 2007
... peroxide NADPH oxidase (NOX) NOX4 NOX4 inhibitor reactive oxygen species (ROS) superoxide NOX4 is a member of the NOX (NADPH oxidase) family of NADPH oxidases. These enzymes transport electrons from cytoplasmic NADPH across cell and organelle membranes to generate superoxide (O 2...
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Biochem J (2007) 405 (3): 559–568.
Published: 13 July 2007
... factor (Hb-EGF) matrix metalloproteinase (MMP) mobile phone irradiation NADH oxidase reactive oxygen species (ROS) The intensive use of mobile or cellular phones in the last 20 years has aroused concern about possible health problems that may be caused by the microwave irradiation which...
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Biochem J (2007) 405 (1): 1–9.
Published: 13 June 2007
... phosphorylation reactive oxygen species (ROS) tricarboxylic acid cycle The goal of oxidative phosphorylation is the transfer of electrons through a series of acceptor cytochromes in order to generate a proton gradient within the inner mitochondrial membrane ( Scheme 2 ). The potential energy...
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Biochem J (2007) 402 (2): 271–278.
Published: 12 February 2007
... 10 2006 The Biochemical Society, London 2007 lipopolysaccharide mitochondria mitogen-activated protein kinase (MAPK) reactive oxygen species (ROS) signalling uncoupling protein 2 (UCP2) UCP2 (uncoupling protein 2) is a carrier protein located in the inner mitochondrial...
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Biochem J (2005) 390 (2): 377–394.
Published: 23 August 2005
... reactive oxygen species (ROS) reperfusion The heart is a pump that converts chemical energy into mechanical work. The power produced by cardiac muscle is generated almost entirely by the oxidation of carbon fuels with oxygen, and to a great extent the fuels are provided by coronary (myocardial...
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Biochem J (2005) 387 (1): 47–55.
Published: 22 March 2005
... pstorz@bidmc.harvard.edu ). 23 8 2004 26 10 2004 4 11 2004 4 11 2004 The Biochemical Society, London 2005 A20 apoptosis necrosis nuclear factor κB (NF-κB) oxidative stress reactive oxygen species (ROS) ROS (reactive oxygen species) are metabolic by-products...
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Biochem J (2004) 382 (2): 641–650.
Published: 24 August 2004
... protein (HSP) matrixassisted laser-desorption ionization–time-of-flight mass spectrometry (MALDI–TOF-MS) oxidative stress reactive oxygen species (ROS) Arsenic is a well-known carcinogen and possibly acts as a tumour promoter in the process of carcinogenesis [ 1 – 4 ]. Although arsenic has been...
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Biochem J (2004) 381 (3): e1.
Published: 27 July 2004
... Society, London 2004 glutathione glutathionylation kinase mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase kinase (MEKK1) oxidative stress reactive oxygen species (ROS) 25 5 2004 26 5 2004 26 5 2004 1 To whom correspondence should...
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Biochem J (2004) 380 (2): 393–400.
Published: 01 June 2004
... The Biochemical Society, London ©2004 2004 catalase A mitochondria peroxisome protein co-targeting reactive oxygen species (ROS) Saccharomyces cerevisiae Abbreviations used: Cox3, cytochrome c oxidase subunit III; CPY, carboxypeptidase Y; Cta1p, catalase A protein; GFP, green fluorescent...