Skip Nav Destination
1-11 of 11
Biochem J (2016) 473 (15): 2315–2329.
Published: 28 July 2016
... firstname.lastname@example.org . 3 3 2016 20 4 2016 22 4 2016 © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2016 biosynthetic diversity convergent evolution polyamine putrescine spermidine spermine Another prominent...
Biochem J (2013) 452 (3): 423–432.
Published: 31 May 2013
...Radika Soysa; Hanka Venselaar; Jacqueline Poston; Buddy Ullman; Marie-Pierre Hasne The TcPOT1.1 gene from Trypanosoma cruzi encodes a high affinity putrescine-cadaverine transporter belonging to the APC (amino acid/polyamine/organocation) transporter superfamily. No experimental three-dimensional...
Includes: Supplementary data
Biochem J (2005) 392 (2): 335–344.
Published: 22 November 2005
... harvesting. Polyamines were depleted by incubation in 5 mM DFMO. We have previously reported that maximal polyamine depletion occurs after 4 days of treatment with 5 mM DFMO [ 4 ]. Within 6 h of DFMO treatment putrescine was undetectable, spermidine was absent after 24 h, and 40% of spermine remained after 4...
Biochem J (2003) 376 (1): 1–14.
Published: 15 November 2003
...-regulated genes linked to either carcinogenesis or apoptosis. 1 To whom correspondence should be addressed (e-mail email@example.com ). 1 9 2003 16 9 2003 18 9 2003 18 9 2003 The Biochemical Society, London ©2003 2003 apoptosis cancer cell growth putrescine...
John L.A. MITCHELL, Aviva LEYSER, Michelle S. HOLTORFF, Jill S. BATES, Benjamin FRYDMAN, Aldonia L. VALASINAS, Venodhar K. REDDY, Laurence J. MARTON
Biochem J (2002) 366 (2): 663–671.
Published: 01 September 2002
...John L.A. MITCHELL; Aviva LEYSER; Michelle S. HOLTORFF; Jill S. BATES; Benjamin FRYDMAN; Aldonia L. VALASINAS; Venodhar K. REDDY; Laurence J. MARTON The polyamines spermidine and spermine and their diamine precursor putrescine are essential for mammalian cell growth and viability, and strategies...
Biochem J (2001) 360 (3): 657–665.
Published: 10 December 2001
...Yong-Sun LEE; Young-Dong CHO The cDNA encoding ornithine decarboxylase (ODC; EC 18.104.22.168), a key enzyme in putrescine and polyamine biosynthesis, has been cloned from Nicotiana glutinosa (GenBank® AF 323910), and was expressed in Escherichia coli . The amino acid sequence of N. glutinosa ODC showed...
Suvikki SUPPOLA, Sami HEIKKINEN, Jyrki J. PARKKINEN, Mikko UUSI-OUKARI, Veli-Pekka KORHONEN, Tuomo KEINÄNEN, Leena ALHONEN, Juhani JÄNNE
Biochem J (2001) 358 (2): 343–348.
Published: 24 August 2001
... the control of the mouse metallothionein (MT) I promoter. In comparison with singly transgenic animals overexpressing SSAT, the doubly transgenic mice unexpectedly displayed much more striking signs of activated polyamine catabolism, as exemplified by a massive putrescine accumulation and an extreme reduction...
Biochem J (2000) 351 (2): 439–447.
Published: 10 October 2000
..., an active-transport system allowing the cell to take up polyamines from its environment becomes critical for normal growth [4,5]. In mammalian cells, the major polyamines are spermidine and spermine, with smaller amounts of their precursor putrescine. Spermine is formed by the action...
Biochem J (2000) 350 (3): 645–653.
Published: 08 September 2000
... the high levels of antizyme, endogenous ODC activity was not completely abolished, with 10– 39% remaining, depending on the transgenic line. Additionally, a relatively small decrease (30–32%) in cardiac spermidine content was observed, with levels of putrescine and spermine unaffected. Interestingly...
Biochem J (1999) 344 (3): 633–642.
Published: 08 December 1999
...Kazuei IGARASHI; Keiko KASHIWAGI The polyamine content of cells is regulated by biosynthesis, degradation and transport. In Escherichia coli , the genes for three different polyamine transport systems have been cloned and characterized. Two uptake systems (putrescine-specific and spermidine...
Suvikki SUPPOLA, Marko PIETILÄ, Jyrki J. PARKKINEN, Veli-Pekka KORHONEN, Leena ALHONEN, Maria HALMEKYTÖ, Carl W. PORTER, Juhani JÄNNE
Biochem J (1999) 338 (2): 311–316.
Published: 22 February 1999
... transgenic animals. Liver was the most affected tissue in the MT–SSAT transgenic animals, revealed by putrescine overaccumulation, significant decrease in spermidine concentration and > 90% reduction in the spermine pool. Even though hepatic SSAT mRNA accumulated to massive levels in non-induced...