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Keywords: phospholipase D
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Biochem J (2021) 478 (9): 1749–1767.
Published: 10 May 2021
...Ariela Samantha; Jasmina Damnjanović; Yugo Iwasaki; Hideo Nakano; Alice Vrielink Phospholipase D (PLD) is an enzyme useful for the enzymatic modification of phospholipids. In the presence of primary alcohols, the enzyme catalyses transphosphatidylation of the head group of phospholipid substrates...
Includes: Supplementary data
Biochem J (2005) 391 (2): 285–289.
Published: 10 October 2005
...Nandita S. Raikwar; Rosario F. Bowen; Mark A. Deeg Glycosylphosphatidylinositol (GPI)-specific phospholipase D (GPI-PLD) specifically cleaves GPIs. This phospholipase D is a secreted protein consisting of two domains: an N-terminal catalytic domain and a predicted C-terminal β-propeller. Although...
Biochem J (2005) 389 (1): 241–247.
Published: 21 June 2005
... -acylphosphatidylethanolamines) by a phosphodiesterase of the PLD (phospholipase D) type (NAPE-PLD). Recently, we cloned cDNAs of NAPE-PLD from mouse, rat and human [Okamoto, Morishita, Tsuboi, Tonai and Ueda (2004) J. Biol. Chem. 279 , 5298–5305]. However, it remained unclear whether NAPE-PLD acts on endogenous NAPEs contained...
Biochem J (2005) 389 (1): 207–214.
Published: 21 June 2005
...Soha ZOUWAIL; Trevor R. PETTITT; Stephen K. DOVE; Margarita V. CHIBALINA; Dale J. POWNER; Lee HAYNES; Michael J. O. WAKELAM; Robert H. INSALL PLD (phospholipase D) activity catalyses the generation of the lipid messenger phosphatidic acid, which has been implicated in a number of cellular processes...
Includes: Supplementary data
Biochem J (2004) 381 (3): 655–663.
Published: 27 July 2004
... receptors. At present, however, it is not clear whether the biological effects elicited by Sph are attributable to its conversion into S1P. In the present study, we show that Sph significantly stimulated phospholipase D (PLD) activity in mouse C2C12 myoblasts via a previously unrecognized mechanism...
Biochem J (2004) 378 (2): 649–656.
Published: 01 March 2004
...Momoko YAMADA; Yoshiko BANNO; Yoh TAKUWA; Masahiro KODA; Akira HARA; Yoshinori NOZAWA To examine the roles of PLD (phospholipase D) in the regulation of the apoptotic process, PLD1 and PLD2 were stably overexpressed in S1P 3 -CHO cells [CHO (Chinese-hamster ovary) cells expressing the S1P...
Biochem J (2002) 362 (3): 741–747.
Published: 08 March 2002
... by phospholipase D-catalysed transphosphatidylation. The inward movement after the onset of scrambling was monitored by extraction of the non-internalized probe with BSA. We demonstrate that both the amino group and the size of the headgroup determine the kinetics of lipid scrambling, and that lipids...
Biochem J (2002) 361 (3): 653–661.
Published: 25 January 2002
... be addressed (e-mail david.brindley@ualberta.ca ) 27 9 2001 2 11 2001 15 11 2001 The Biochemical Society, London ©2002 2002 Golgi phosphatidate phospholipase D protein kinase C vesicle transport Abbreviations used: ARF, ADP-ribosylation factor; C 2 -, acetyl; CHO...
Biochem J (2001) 358 (3): 637–646.
Published: 10 September 2001
...Meera NANJUNDAN; Fred POSSMAYER Lipid phosphate phosphohydrolase (LPP) has recently been proposed to have roles in signal transduction, acting sequentially to phospholipase D (PLD) and in attenuating the effects of phospholipid growth factors on cellular proliferation. In this study, LPP activity...
Biochem J (2000) 345 (3): 401–415.
Published: 25 January 2000
...Mordechai LISCOVITCH; Malgorzata CZARNY; Giusy FIUCCI; Xiaoqing TANG Interaction of extracellular-signal molecules with cell-surface receptors often activates a phospholipase D (PLD)-mediated hydrolysis of phosphatidylcholine and other phospholipids, generating phosphatidic acid. The activation...
Biochem J (1999) 344 (2): 605–611.
Published: 24 November 1999
...-kinases), delay the disappearance of these structures and also correspondingly inhibit degradation of FcγRI-mediated immune complexes. In addition these inhibitors delay the initial phase of FcγRI-mediated endocytosis of immune complexes and block the activity of FcγRI-stimulated phospholipase D...
Biochem J (1999) 344 (1): 199–204.
Published: 08 November 1999
... and 2Me-5-HT stimulated phospholipase D (PLD) activity, as measured by the production of phosphatidylethanol and phosphatidylbutanol at the expense of phosphatidic acid (PA). GF 109203X significantly curtailed the 5-HT- and 2Me-5-HT-induced PLD activity and T-cell activation. The PLD/PA pathway stimulated...
Biochem J (1999) 341 (2): 435–444.
Published: 08 July 1999
... is dependent neither on vesicular transport mechanisms nor on freely diffusible, soluble transport proteins. Phosphatidylcholine-derived PA generated by the ADP-ribosylation-factor-stimulated phospholipase D pathway was found to accumulate label, reflecting the rapid cycling of PA to DG, and back...
Biochem J (1999) 337 (2): 263–268.
Published: 08 January 1999
...Remko R. BOSCH; Rolf L. L. SMEETS; Frank SLEUTELS; Anjana M. P. PATEL; Sjenet E. Van EMST-De VRIES; Jan Joep H. H. M. DE PONT; Peter H. G. M. WILLEMS Receptor-mediated activation of phosphatidylcholine phosphatidohydrolase or phospholipase D (PLD) was studied in Chinese hamster ovary (CHO) cells...