...Mark G. Waugh Phosphatidylinositol 4-phosphate (PI4P) is a membrane glycerophospholipid and a major regulator of the characteristic appearance of the Golgi complex as well as its vesicular trafficking, signalling and metabolic functions. Phosphatidylinositol 4-kinases, and in particular...

...). Published by Portland Press Limited on behalf of the Biochemical Society 2019 lipid transfer phosphatidylinositol phosphoinositide 3-kinase PTEN transmembrane proteins PPIs (polyphosphoinositides) are reversibly phosphorylated derivatives of the membrane phospholipid phosphatidylinositol...

...Shamshad Cockcroft; Padinjat Raghu Phospholipase C (PLC) is a receptor-regulated enzyme that hydrolyses phosphatidylinositol 4,5-bisphosphate (PI(4,5)P 2 ) at the plasma membrane (PM) triggering three biochemical consequences, the generation of soluble inositol 1,4,5-trisphosphate (IP 3 ), membrane...

... was 2000-fold more active as a PtdIns5 P 4-kinase than the IIβ isoform. Overall the results suggest a function of PtdIns5 P 4-kinase IIβ may be to target the more active IIα isoform into the nucleus. DT40 cell genomic tagging nuclear signalling phosphatidylinositol phosphatidylinositol 5...

... lipid pools phosphatidylinositol phosphatidylinositol synthase (PIS) The complex interplay of physiological processes in eukaryotic organisms, including plants, relies in part upon the regulation by inositol-containing lipids such as polyphosphoinositides [ 1 – 4 ]. As regulatory functions...

... recombinant eukaryotic PI-PLC, inhibitors and direct phospholipid analysis using ESI-MS (electrospray ionization mass spectrometry). PtdIns (phosphatidylinositol) species analysis by ESI-MS indicates that the chromatin-bound NE precursor vesicles are enriched for specific PtdIns species. Moreover, during GTP...

...Yasu S. MORITA; John H. PATTERSON; Helen BILLMAN-JACOBE; Malcolm J. McCONVILLE All mycobacterial species, including pathogenic Mycobacterium tuberculosis , synthesize an abundant class of phosphatidylinositol mannosides (PIMs) that are essential for normal growth and viability. These glycolipids...

...Mini P. SAJAN; Gautam BANDYOPADHYAY; Yoshinori KANOH; Mary L. STANDAERT; Michael J. QUON; Brent C. REED; Ivan DIKIC; Robert V. FARESE Sorbitol, ‘osmotic stress’, stimulates GLUT4 glucose transporter translocation to the plasma membrane and glucose transport by a phosphatidylinositol (PI) 3-kinase...

... phosphatidylinositol Biochem. J. (1999) 341, 571 576 (Printed in Great Britain) 571 Role of lipid packing in the activity of phospholipase C-d1 as determined by hydrostatic pressure measurements Mario REBECCHI*, Marjorie BONHOMME‹ and Suzanne SCARLATA‹" *Department of Anesthesiology, State University of New York...