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Keywords: pancreatic cancer
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Biochem J (2021) 478 (20): 3757–3774.
Published: 21 October 2021
... collectively, these studies demonstrate a functional link between PEPT1 and extracellular protein breakdown in the tumor microenvironment as a key determinant of pancreatic cancer growth, thus identifying PEPT1 as a potential therapeutic target for PDAC. Immunofluorescence studies were performed...
Includes: Supplementary data
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Biochem J (2020) 477 (19): 3899–3910.
Published: 16 October 2020
..., carbidopa but not dopamine exhibited AhR activity in BxPC3 pancreatic cancer cells whereas minimal activity was observed for both compounds in Panc1 pancreatic cancer cells. In contrast with a previous report, the induction responses and cytotoxicity of carbidopa was observed only at high concentrations...
Includes: Supplementary data
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Biochem J (2017) 474 (22): 3763–3765.
Published: 06 November 2017
..., and this compound inhibits pancreatic cancer cell and tumor growth. These results are consistent with activities of other AhR-active compounds that inhibit carcinogenesis. Like carbidopa, these chemicals are selective AhR modulators with potential clinical applications that are AhR-dependent. Correspondence...
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Biochem J (2017) 474 (20): 3391–3402.
Published: 29 September 2017
...Jiro Ogura; Seiji Miyauchi; Kazumi Shimono; Shengping Yang; Sathisha Gonchigar; Vadivel Ganapathy; Yangzom D. Bhutia Carbidopa is used with l -DOPA ( l -3,4-dihydroxyphenylalanine) to treat Parkinson's disease (PD). PD patients exhibit lower incidence of most cancers including pancreatic cancer...
Includes: Supplementary data
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