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Keywords: nuclear localization
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Biochem J (2016) 473 (24): 4593–4607.
Published: 09 December 2016
..., in vitro . We report that FGF10 harbours two putative nuclear localization sequences (NLSs), termed NLS1 and NLS2, which individually or co-operatively promote nuclear translocation of FGF10. Furthermore, FGF10 localizes to a subset of dense fibrillar components of the nucleolus. G138E falls within NLS1...
Includes: Supplementary data
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Biochem J (2015) 468 (2): 345–352.
Published: 22 May 2015
... protein (RBBP)4/7 and methyl DNA-binding domain protein (MBD)3. Novel protein associations with CHD5–NuRD may account for the functional differences compared with CHD4–NuRD. chromodomain helicase DNA-binding protein 5 ( CHD5 ) neuroblastoma nuclear localization nucleosome remodelling histone...
Includes: Supplementary data
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Biochem J (2014) 458 (2): 375–385.
Published: 14 February 2014
... the trafficking of the toxin within cells. Observations made in this regard revealed that the abrin A chain, after being released into the cytosol, is sequestered into the nucleus through interaction with a cellular protein of ~25 kDa, BASP1 (brain acid-soluble protein 1). The nuclear localization of the A chain...
Includes: Supplementary data
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Biochem J (2010) 432 (1): 77–87.
Published: 25 October 2010
...-specific N-terminus of Fbw7α are phosphorylated in a PKC-dependent manner, both in vitro and in mammalian cells (Ser 10 and Ser 18 ). Mutational analyses reveal that phosphorylation of Fbw7α at Ser 10 can regulate its nuclear localization. Cancer-associated mutations in nearby residues (K11R...
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Biochem J (2007) 408 (3): 335–345.
Published: 28 November 2007
... 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 euchromatin Ins(1,3,4,5,6) P 5 2-kinase (IP5K) in situ hybridization nuclear localization stress granule There is a considerable literature describing the signalling functions and metabolic pathways...
Includes: Supplementary data
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Biochem J (2007) 403 (3): 397–407.
Published: 12 April 2007
... also directly acetylates Max in vitro at these three residues. Interestingly, the three Max residues acetylated in vivo and in vitro by p300 are important for Max nuclear localization and Max-mediated suppression of Myc transactivation. These results uncover novel post-translational modifications...
Includes: Supplementary data
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Biochem J (2001) 355 (2): 473–479.
Published: 06 April 2001
... isoform has a perinuclear localization, and is associated with the cytoskeleton; this targeting, due to signals within the 3′-untranslated region (3′-UTR), facilitates nuclear localization of MT-1 during S-phase [Levadoux, Mahon, Beattie, Wallace and Hesketh (1999) J. Biol. Chem. 274 , 34961-34966]. Using...
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