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Keywords: mucin
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Biochem J (2021) 478 (8): 1585–1603.
Published: 28 April 2021
...D. Judy Shon; Angel Kuo; Michael J. Ferracane; Stacy A. Malaker Epithelial surfaces throughout the body are coated by mucins, a class of proteins carrying domains characterized by a high density of O-glycosylated serine and threonine residues. The resulting mucosal layers form crucial host-microbe...
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Biochem J (2019) 476 (16): 2281–2295.
Published: 22 August 2019
...Hannah Schneider; Evelin Berger; Brendan Dolan; Beatriz Martinez-Abad; Liisa Arike; Thaher Pelaseyed; Gunnar C. Hansson Transmembrane mucin MUC17 is an integral part of the glycocalyx as it covers the brush border membrane of small intestinal enterocytes and presents an extended O -glycosylated...
Includes: Supplementary data
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Biochem J (2012) 444 (2): 211–218.
Published: 11 May 2012
...Gaspar E. Cánepa; Maria Sol Degese; Alexandre Budu; Celia R. S. Garcia; Carlos A. Buscaglia TSSA (trypomastigote small surface antigen) is a polymorphic mucin-like molecule displayed on the surface of Trypanosoma cruzi trypomastigote forms. To evaluate its functional properties, we undertook...
Includes: Supplementary data
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Biochem J (2011) 438 (2): 303–313.
Published: 12 August 2011
...Ivana Urban; Lucía Boiani Santurio; Agustina Chidichimo; Hai Yu; Xi Chen; Juan Mucci; Fernán Agüero; Carlos A. Buscaglia The surface of the protozoan Trypanosoma cruzi is covered by a dense coat of mucin-type glycoconjugates, which make a pivotal contribution to parasite protection and host immune...
Includes: Supplementary data
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Biochem J (2009) 417 (3): 673–683.
Published: 16 January 2009
..., including a sialyl-Tn antigen that is one of the typical tumour-associated carbohydrate antigens expressed on various mucins. Many epithelial tumours secrete mucins into tissues and/or the bloodstream. Mouse mammary adenocarcinoma cells, TA3-Ha, produce a mucin named epiglycanin, but a subline of them, TA3...
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Biochem J (2006) 399 (1): 121–129.
Published: 13 September 2006
...Martin E. Lidell; Gunnar C. Hansson MUC5AC is the main gel-forming mucin expressed by goblet cells of the airways and stomach where it protects the underlying epithelia. We expressed the C-terminal cysteine-rich part of the human MUC5AC mucin in CHO-K1 cells (Chinese-hamster ovary K1 cells) where...
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Biochem J (2004) 384 (2): E3.
Published: 23 November 2004
... structures of mucin oligosaccharides, and in demonstrating that there are variations in structure along the sections of the gut. In contrast to previous studies, these results described by Robbe et al. show some correlation with the activities of enzymes synthesizing mucin oligosaccharides in the human colon...
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Biochem J (2004) 379 (3): 765–775.
Published: 01 May 2004
...Sara LINDÉN; Thomas BORÉN; André DUBOIS; Ingemar CARLSTEDT Mucins isolated from the stomach of Rhesus monkey are oligomeric glycoproteins with a similar mass, density, glycoform profile and tissue localization as human MUC5AC and MUC6. Antibodies raised against the human mucins recognize those from...
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Biochem J (2002) 368 (1): 41–48.
Published: 15 November 2002
... that the soluble form is created early in transit to the cell surface. These studies provide the first clear evidence that membrane mucins can be released from cells by an intracellular proteolytic mechanism that leads to secretion of the soluble form of the mucin. 1 To whom correspondence should be addressed...
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