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miR-429 regulates alveolar macrophage inflammatory cytokine production and is involved in LPS-induced acute lung injury

Ji Xiao, Jing Tang, Quan Chen, Dan Tang, Meimei Liu, Min Luo, Yan Wang, Jiazheng Wang, Zhenyu Zhao, Chaoke Tang, Deming Wang, Zhongcheng Mo

Biochem J (2015) 471 (2): 281–291.

https://doi.org/10.1042/BJ20131510

Published: 02 October 2015

...Ji Xiao; Jing Tang; Quan Chen; Dan Tang; Meimei Liu; Min Luo; Yan Wang; Jiazheng Wang; Zhenyu Zhao; Chaoke Tang; Deming Wang; Zhongcheng Mo p38 MAPK (mitogen-activated protein kinase) is a critical regulator in lung inflammation. It can be inactivated by DUSP1 (dual-specificity phosphatase 1) which...

View article titled, miR-429 regulates alveolar macrophage inflammatory cytokine production and is involved in LPS-induced acute lung injury

Includes: Supplementary data

Articles

Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca2+- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells

Kennedy MAKONDO, Kazuhiro KIMURA, Naoki KITAMURA, Takanori KITAMURA, Daisuke YAMAJI, Bae Dong JUNG, Masayuki SAITO

Biochem J (2003) 374 (1): 63–69.

https://doi.org/10.1042/bj20030326

Published: 15 August 2003

...@vetmed.hokudai.ac.jp ). 27 2 2003 19 5 2003 21 5 2003 21 5 2003 The Biochemical Society, London ©2003 2003 hepatocyte growth factor (HGF) mitogen-activated protein kinase nitric oxide nitric oxide synthase wortmannin Abbreviations used: BAEC, bovine aortic endothelial...

View article titled, Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca2+- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells

Articles

Ets2 and protein kinase Cepsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells

Ralph K. LINDEMANN, Melanie BRAIG, Craig A. HAUSER, Alfred NORDHEIM, Jürgen DITTMER

Biochem J (2003) 372 (3): 787–797.

https://doi.org/10.1042/bj20030046

Published: 15 June 2003

... of P3-dependent PTHrP expression in MCF-7 cells. Mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinase (ERK) kinase 1 (MEK-1)/ERK1/2 inhibitor PD98059 interfered with this activity. Promoter studies revealed that the PMA effect depended on the Ets and stimulating protein-1 (Sp1...

View article titled, Ets2 and protein kinase Cepsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells

Articles

Polymorphic glutathione S-transferase subunit 3 of rat liver exhibits different susceptibilities to carbon tetrachloride: differences in their interactions with heat-shock protein 90

Jun MAYAMA, Takayuki KUMANO, Makoto HAYAKARI, Takehiko YAMAZAKI, Shu AIZAWA, Toshihiro KUDO, Shigeki TSUCHIDA

Biochem J (2003) 372 (2): 611–616.

https://doi.org/10.1042/bj20021788

Published: 01 June 2003

... inactivation due to CCl 4 . 1 To whom correspondence should be addressed (e-mail tsuchida@cc.hirosaki-u.ac.jp ). 18 11 2002 24 2 2003 27 2 2003 3 3 2003 The Biochemical Society, London ©2003 2003 glutathiolation glyoxalase I mitogen-activated protein kinase oxidative...

View article titled, Polymorphic glutathione S-transferase subunit 3 of rat liver exhibits different susceptibilities to carbon tetrachloride: differences in their interactions with heat-shock protein 90

Articles

Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells

Charles S.T. HII, Maurizio COSTABILE, George C. MAYNE, Channing J. DER, Andrew W. MURRAY, Antonio FERRANTE

Biochem J (2003) 370 (2): 497–503.

https://doi.org/10.1042/bj20021122

Published: 01 March 2003

... (Printed in Great Britain) 497 Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells Charles S. T. HII*1, Maurizio COSTABILE George C. MAYNE*, Channing J. DER, Andrew W. MURRAY and Antonio FERRANTE*s *Department...

View article titled, Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells

Articles

Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia

Tamara EGGER, Rufina SCHULIGOI, Andrea WINTERSPERGER, Rainer AMANN, Ernst MALLE, Wolfgang SATTLER

Biochem J (2003) 370 (2): 459–467.

https://doi.org/10.1042/bj20021358

Published: 01 March 2003

... protein synthesis in LPS-stimulated BV-2 cells involved activation of the extracellular-signal-regulated kinase 1/2 (ERK1/2) and p38 mitogen-activated protein kinase (MAPK) pathway and was sensitive to the protein kinase C (PKC) inhibitors staurosporine and chelerythrine, and the MAP kinase/ERK kinase 1/2...

View article titled, Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia

Articles

Insulin stimulation of pyruvate dehydrogenase in adipocytes involves two distinct signalling pathways

Sam A. JOHNSON, Richard M. DENTON

Biochem J (2003) 369 (2): 351–356.

https://doi.org/10.1042/bj20020920

Published: 15 January 2003

...Sam A. JOHNSON; Richard M. DENTON In isolated rat adipocytes, the insulin stimulation of pyruvate dehydrogenase can be partially inhibited by inhibitors of PI3K (phosphoinositide 3-kinase) and MEK1/2 (mitogen-activated protein kinase/extracellular signal-regulated kinase kinase). In combination...

View article titled, Insulin stimulation of pyruvate dehydrogenase in adipocytes involves two distinct signalling pathways

Articles

Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein

Angela CLERK, Timothy J. KEMP, Joanne G. HARRISON, Anthony J. MULLEN, Paul J.R. BARTON, Peter H. SUGDEN

Biochem J (2002) 368 (1): 101–110.

https://doi.org/10.1042/bj20021083

Published: 15 November 2002

... to up-regulate its own transcription and, since the c-Jun N-terminal kinase (JNK) family of mitogen-activated protein kinases (MAPKs) phosphorylate c-Jun(Ser-63/73) to increase its transactivating activity, JNKs are thought to be the principal factors involved in c- jun up-regulation. Hypertrophy...

View article titled, Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein

Articles

Differentiation regulates interleukin-1β-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase

Béatrice THOMAS, Sylvie THIRION, Lydie HUMBERT, Lujian TAN, Mary B. GOLDRING, Gilbert BÉRÉZIAT, Francis BERENBAUM

Biochem J (2002) 362 (2): 367–373.

https://doi.org/10.1042/bj3620367

Published: 22 February 2002

... monolayer cultures (alg-) after stimulation with IL-1β. Moreover, IL-1β induced COX-2 expression at 0.01ng/ml in (alg+) cells, whereas a 100-fold higher dose of cytokine was necessary for stimulation in (alg-) cells. SB203580, a selective p38 mitogen-activated protein kinase (MAPK) inhibitor, completely...

View article titled, Differentiation regulates interleukin-1β-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase

Articles

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage

Frédéric BOST, Leslie CARON, Irène MARCHETTI, Christian DANI, Yannick LE MARCHAND-BRUSTEL, Bernard BINÉTRUY

Biochem J (2002) 361 (3): 621–627.

https://doi.org/10.1042/bj3610621

Published: 25 January 2002

..., but not the c-Jun N-terminal kinase, p38 mitogen-activated protein kinase or phosphoinositide 3-kinase pathways. To investigate the role of ERK activation, co-treatment of RA with PD98059, a specific inhibitor of the ERK signalling pathway, prevented both adipocyte formation and expression of the adipogenic...

View article titled, Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage

Articles

HstK, a cyanobacterial protein with both a serine/threonine kinase domain and a histidine kinase domain: implication for the mechanism of signal transduction

Vincent PHALIP, Jian-Hong LI, Cheng-Cai ZHANG

Biochem J (2001) 360 (3): 639–644.

https://doi.org/10.1042/bj3600639

Published: 10 December 2001

... for the response to high osmolarity in the S. cerevisiae heterologous system. The unusual multidomain structure of HstK suggests that a two-component system could be directly coupled to Ser/Thr kinases in the same signal transduction pathway. Anabaena mitogen-activated protein kinase protein kinase signal...

View article titled, HstK, a cyanobacterial protein with both a serine/threonine kinase domain and a histidine kinase domain: implication for the mechanism of signal transduction

Articles

Endothelin-1 induces phosphorylation of GATA-4 transcription factor in the HL-1 atrial-muscle cell line

Kazumi KITTA, Sophie A. CLÉMENT, Jane REMEIKA, Jeffrey B. BLUMBERG, Yuichiro J. SUZUKI

Biochem J (2001) 359 (2): 375–380.

https://doi.org/10.1042/bj3590375

Published: 08 October 2001

... of the GATA-4 band also occurred on SDS/PAGE as monitored by immunoblotting. The in vitro treatment of nuclear extracts with λ-protein phosphatase abolished the upward shift, indicating that GATA-4 was phosphorylated. ET-1 activated the p44/42 mitogen-activated protein kinase (MAPK) and the MAPK kinase (MEK...

View article titled, Endothelin-1 induces phosphorylation of GATA-4 transcription factor in the HL-1 atrial-muscle cell line

Articles

c-Jun N-terminal kinase-interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes

Stephen G. FINN, Martin DICKENS, Stephen J. FULLER

Biochem J (2001) 358 (2): 489–495.

https://doi.org/10.1042/bj3580489

Published: 24 August 2001

... to constitutively active Ras or Raf, but attenuated reporter gene activation induced by a constitutively active mutant of mitogen-activated protein kinase kinase kinase 1 (MEKK1), an upstream kinase that preferentially activates JNKs, by 50%. Overexpression of JIP-1 also significantly reduced the increase in cell...

View article titled, c-Jun N-terminal kinase-interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes

Articles

Cell hydration controls autophagosome formation in rat liver in a microtubule-dependent way downstream from p38MAPK activation

Stephan VOM DAHL, Frank DOMBROWSKI, Marcus SCHMITT, Freimut SCHLIESS, Ulrich PFEIFER, Dieter HÄUSSINGER

Biochem J (2001) 354 (1): 31–36.

https://doi.org/10.1042/bj3540031

Published: 08 February 2001

... volume, colchicine, mitogen-activated protein kinase, protein degradation, SB 203580. MATERIALS AND METHODS Liver perfusion Livers, from male Wistar rats (160 230 g) fed on a standard chow, were perfused in an open non-recirculating manner as described previously [15]. The perfusion medium was bicarbon...

View article titled, Cell hydration controls autophagosome formation in rat liver in a microtubule-dependent way downstream from p38MAPK activation

Articles

Ischaemia induces changes in the association of the binding protein 4E-BP1 and eukaryotic initiation factor (eIF) 4G to eIF4E in differentiated PC12 cells

M. Elena MARTÍN, Francisco M. MUÑOZ, Matilde SALINAS, Juan L. FANDO

Biochem J (2000) 351 (2): 327–334.

https://doi.org/10.1042/bj3510327

Published: 10 October 2000

... of PC12 cells with the specific p38 mitogen-activated protein kinase inhibitor SB203580 induced eIF4E dephosphorylation but did not cause any effect on protein synthesis rate. Rapamycin, the inhibitor of mammalian target of rapamycin (‘mTOR’), but not PD98059, the inhibitor of extracellular signal...

View article titled, Ischaemia induces changes in the association of the binding protein 4E-BP1 and eukaryotic initiation factor (eIF) 4G to eIF4E in differentiated PC12 cells

Articles

Bradykinin activates the Janus-activated kinase/signal transducers and activators of transcription (JAK/STAT) pathway in vascular endothelial cells: localization of JAK/STAT signalling proteins in plasmalemmal caveolae

Hong JU, Virginia J. VENEMA, Haiying LIANG, M. Brennan HARRIS, Rong ZOU, Richard C. VENEMA

Biochem J (2000) 351 (1): 257–264.

https://doi.org/10.1042/bj3510257

Published: 26 September 2000

... recently, however, has it been shown that these signalling pathways Abbreviations used: BK, bradykinin ; VSMC, vascular smooth-muscle cell ; B2R, B2 receptor ; MAPK, mitogen-activated protein kinase ; JAK, Janus- activated kinase ; STAT, signal transducers and activators of transcription ; Ang II...

View article titled, Bradykinin activates the Janus-activated kinase/signal transducers and activators of transcription (JAK/STAT) pathway in vascular endothelial cells: localization of JAK/STAT signalling proteins in plasmalemmal caveolae

Articles

Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts

Pauliina LAINE, Niina REUNANEN, Laura RAVANTI, Marco FOSCHI, Manoranjan SANTRA, V. Renato IOZZO, Veli-Matti KÄHÄRI

Biochem J (2000) 349 (1): 19–25.

https://doi.org/10.1042/bj3490019

Published: 26 June 2000

... proteoglycan mitogen-activated protein kinase Biochem. J. (2000) 349, 19 25 (Printed in Great Britain) 19 Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts Pauliina LAINE Niina REUNANEN Laura RAVANTI Marco FOSCHI, Manoranjan...

View article titled, Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts

Articles

Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa

Benjamin TURGEON, Marc K. SABA-EL-LEIL, Sylvain MELOCHE

Biochem J (2000) 346 (1): 169–175.

https://doi.org/10.1042/bj3460169

Published: 08 February 2000

...Benjamin TURGEON; Marc K. SABA-EL-LEIL; Sylvain MELOCHE MAP (mitogen-activated protein) kinases are a family of serine/threonine kinases that have a pivotal role in signal transduction. Here we report the cloning and characterization of a mouse homologue of extracellular-signal-regulated protein...

View article titled, Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa

Articles

14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylation

Paulus C. J. VAN DER HOEVEN, José C. M. VAN DER WAL, Paula RUURS, Marc C. M. VAN DIJK, Wim J. VAN BLITTERSWIJK

Biochem J (2000) 345 (2): 297–306.

https://doi.org/10.1042/bj3450297

Published: 10 January 2000

... binds both PKC-f (at phospho-Ser-186) and Raf-1 in INTRODUCTION Activation of the mitogen-activated protein kinase (MAPK or extracellular-signal-regulated protein kinase, ERK) pathway is a central event in the response of cells to mitogenic stimuli. In this pathway, Raf-1 is recruited to the plasma...

View article titled, 14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylation

Articles

Protein kinase signalling pathways involved in the up-regulation of the rat α1(I) collagen gene by transforming growth factor β1 and bone morphogenetic protein 2 in osteoblastic cells

Sandrine PALCY, David GOLTZMAN

Biochem J (1999) 343 (1): 21–27.

https://doi.org/10.1042/bj3430021

Published: 24 September 1999

... the stabilization of α1(I) collagen mRNA, and required new protein synthesis. In addition, TGFβ 1 - and BMP-2-induced increases in α1(I) collagen mRNA levels were both dependent on protein kinase C and protein tyrosine kinase activities. Furthermore, the mitogen-activated protein kinase (MAPK) [MAPK/extracellular...

View article titled, Protein kinase signalling pathways involved in the up-regulation of the rat α1(I) collagen gene by transforming growth factor β1 and bone morphogenetic protein 2 in osteoblastic cells

Articles

Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor

Brygida BERSE, Ignacio LOPEZ-COVIELLA, J. Krzysztof BLUSZTAJN

Biochem J (1999) 342 (2): 301–308.

https://doi.org/10.1042/bj3420301

Published: 24 August 1999

... activated mitogen-activated protein kinase and increased cytosolic free calcium concentrations, confirming the reconstitution of TrkA-mediated signalling pathways. The expression of ChAT and VAChT mRNA, as well as ACh content, were coordinately up-regulated by NGF in SN56- trkA transfectants. None...

View article titled, Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor

Articles

Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters

Renata JASINSKA, Qiu-Xia ZHANG, Carlos PILQUIL, Indrapal SINGH, James XU, Jay DEWALD, Deirdre A. DILLON, Luc G. BERTHIAUME, George M. CARMAN, David W. WAGGONER, David N. BRINDLEY

Biochem J (1999) 340 (3): 677–686.

https://doi.org/10.1042/bj3400677

Published: 08 June 1999

..., Seattle, WA 98119, U.S 1 To whom correspondence should be addressed (e-mail david.brindley@ualberta.ca). 15 1 1999 8 3 1999 1 4 1999 The Biochemical Society, London © 1999 1999 ceramide 1-phosphate DNA synthesis lysophosphatidate mitogen-activated protein kinase...

View article titled, Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters

Articles

Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors

Paul G. WYLIE, R. A. John CHALLISS, Jonathan L. BLANK

Biochem J (1999) 338 (3): 619–628.

https://doi.org/10.1042/bj3380619

Published: 08 March 1999

... correspondence should be addressed (e-mail jb48@le.ac.uk ). 1 10 1998 2 12 1998 5 1 1999 The Biochemical Society, London © 1999 1999 calcium G-protein-coupled receptor mitogen-activated protein kinase protein kinase C stress-activated protein kinase Biochem. J. (1999) 338...

View article titled, Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors

Articles

Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42

W. DAVIS, Leonard R. STEPHENS, Phillip T. HAWKINS, Jeremy SAKLATVALA

Biochem J (1999) 338 (2): 387–392.

https://doi.org/10.1042/bj3380387

Published: 22 February 1999

...@cxwms.ac.uk ). 30 6 1998 1 12 1998 17 12 1998 The Biochemical Society, London © 1999 1999 lethal toxin mitogen-activated protein kinase Ras Rho GTPases toxin B Biochem. J. (1999) 338, 387 392 (Printed in Great Britain) 387 Synergistic activation of JNK/SAPK by interleukin-1...

View article titled, Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42

Articles

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways

Koichi GONDA, Hiroyuki OKAMOTO, Noriko TAKUWA, Yutaka YATOMI, Hiroshi OKAZAKI, Takeshi SAKURAI, Sadao KIMURA, Rannar SILLARD, Kiyonori HARII, Yoh TAKUWA

Biochem J (1999) 337 (1): 67–75.

https://doi.org/10.1042/bj3370067

Published: 17 December 1998

... mitogen-activated protein kinase (MAPK) in a PTX-sensitive and Ras-dependent manner. S1P also induced the activation of two stress-activated MAPKs, c-Jun N-terminal kinase and p38, in a manner that was totally insensitive to PTX. In CHO-AGR16 cells, S1P induced stress-fibre formation, with an increase...

View article titled, The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways

NARROW

miR-429 regulates alveolar macrophage inflammatory cytokine production and is involved in LPS-induced acute lung injury

Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca2+- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells

Ets2 and protein kinase Cepsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells

Polymorphic glutathione S-transferase subunit 3 of rat liver exhibits different susceptibilities to carbon tetrachloride: differences in their interactions with heat-shock protein 90

Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells

Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia

Insulin stimulation of pyruvate dehydrogenase in adipocytes involves two distinct signalling pathways

Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein

Differentiation regulates interleukin-1β-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage

HstK, a cyanobacterial protein with both a serine/threonine kinase domain and a histidine kinase domain: implication for the mechanism of signal transduction

Endothelin-1 induces phosphorylation of GATA-4 transcription factor in the HL-1 atrial-muscle cell line

c-Jun N-terminal kinase-interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes

Cell hydration controls autophagosome formation in rat liver in a microtubule-dependent way downstream from p38MAPK activation

Ischaemia induces changes in the association of the binding protein 4E-BP1 and eukaryotic initiation factor (eIF) 4G to eIF4E in differentiated PC12 cells

Bradykinin activates the Janus-activated kinase/signal transducers and activators of transcription (JAK/STAT) pathway in vascular endothelial cells: localization of JAK/STAT signalling proteins in plasmalemmal caveolae

Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts

Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa

14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylation

Protein kinase signalling pathways involved in the up-regulation of the rat α1(I) collagen gene by transforming growth factor β1 and bone morphogenetic protein 2 in osteoblastic cells

Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor

Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters

Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors

Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways

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