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Keywords: mitogen-activated protein kinase
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Biochem J (2015) 471 (2): 281–291.
Published: 02 October 2015
...Ji Xiao; Jing Tang; Quan Chen; Dan Tang; Meimei Liu; Min Luo; Yan Wang; Jiazheng Wang; Zhenyu Zhao; Chaoke Tang; Deming Wang; Zhongcheng Mo p38 MAPK (mitogen-activated protein kinase) is a critical regulator in lung inflammation. It can be inactivated by DUSP1 (dual-specificity phosphatase 1) which...
Includes: Supplementary data
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Biochem J (2003) 370 (2): 459–467.
Published: 01 March 2003
... protein synthesis in LPS-stimulated BV-2 cells involved activation of the extracellular-signal-regulated kinase 1/2 (ERK1/2) and p38 mitogen-activated protein kinase (MAPK) pathway and was sensitive to the protein kinase C (PKC) inhibitors staurosporine and chelerythrine, and the MAP kinase/ERK kinase 1/2...
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Biochem J (2003) 369 (2): 351–356.
Published: 15 January 2003
...Sam A. JOHNSON; Richard M. DENTON In isolated rat adipocytes, the insulin stimulation of pyruvate dehydrogenase can be partially inhibited by inhibitors of PI3K (phosphoinositide 3-kinase) and MEK1/2 (mitogen-activated protein kinase/extracellular signal-regulated kinase kinase). In combination...
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Biochem J (2002) 361 (3): 621–627.
Published: 25 January 2002
..., but not the c-Jun N-terminal kinase, p38 mitogen-activated protein kinase or phosphoinositide 3-kinase pathways. To investigate the role of ERK activation, co-treatment of RA with PD98059, a specific inhibitor of the ERK signalling pathway, prevented both adipocyte formation and expression of the adipogenic...
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Biochem J (2001) 359 (2): 375–380.
Published: 08 October 2001
... of the GATA-4 band also occurred on SDS/PAGE as monitored by immunoblotting. The in vitro treatment of nuclear extracts with λ-protein phosphatase abolished the upward shift, indicating that GATA-4 was phosphorylated. ET-1 activated the p44/42 mitogen-activated protein kinase (MAPK) and the MAPK kinase (MEK...
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Biochem J (2001) 358 (2): 489–495.
Published: 24 August 2001
... to constitutively active Ras or Raf, but attenuated reporter gene activation induced by a constitutively active mutant of mitogen-activated protein kinase kinase kinase 1 (MEKK1), an upstream kinase that preferentially activates JNKs, by 50%. Overexpression of JIP-1 also significantly reduced the increase in cell...
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Biochem J (2000) 346 (1): 169–175.
Published: 08 February 2000
...Benjamin TURGEON; Marc K. SABA-EL-LEIL; Sylvain MELOCHE MAP (mitogen-activated protein) kinases are a family of serine/threonine kinases that have a pivotal role in signal transduction. Here we report the cloning and characterization of a mouse homologue of extracellular-signal-regulated protein...
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Biochem J (2000) 345 (2): 297–306.
Published: 10 January 2000
... binds both PKC-f (at phospho-Ser-186) and Raf-1 in INTRODUCTION Activation of the mitogen-activated protein kinase (MAPK or extracellular-signal-regulated protein kinase, ERK) pathway is a central event in the response of cells to mitogenic stimuli. In this pathway, Raf-1 is recruited to the plasma...
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Biochem J (1999) 338 (3): 619–628.
Published: 08 March 1999
... was insensitive to pertussis toxin (PTX), consistent with a INTRODUCTION Mitogen-activated protein kinases (MAPKs) are activated by a diverse array of extracellular stimuli and regulate a variety of cellular responses (for reviews see [1 4 MAPK family members include the extracellular signal-regulated kinases...
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Biochem J (1999) 338 (2): 387–392.
Published: 22 February 1999
...@cxwms.ac.uk ). 30 6 1998 1 12 1998 17 12 1998 The Biochemical Society, London © 1999 1999 lethal toxin mitogen-activated protein kinase Ras Rho GTPases toxin B Biochem. J. (1999) 338, 387 392 (Printed in Great Britain) 387 Synergistic activation of JNK/SAPK by interleukin-1...
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