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Keywords: mammary gland
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Biochem J (2022) 479 (9): 995–1006.
Published: 12 May 2022
...Christine J. Watson The mammary gland provides a spectacular example of physiological cell death whereby the cells that produce milk during lactation are removed swiftly, efficiently, and without inducing inflammation upon the cessation of lactation. The milk-producing cells arise primarily during...
Biochem J (2013) 454 (2): 345–357.
Published: 09 August 2013
... are expressed at different levels in a variety of mouse tissues, including the mammary gland, where they are differentially regulated at successive developmental stages. The longer mRNA species is prevelant during lactation, whereas the shorter is induced after weaning. In 3D cultures, where expression...
Includes: Supplementary data
Biochem J (2013) 449 (2): 401–413.
Published: 14 December 2012
... model to assess the role of Cx43 in mammary gland development and function. We previously reported that severely compromised Cx43 function delayed mammary gland development and impaired milk ejection in mice that harboured a G60S Cx43 mutant, yet there are no reports of lactation defects in ODDD...
Biochem J (2010) 428 (3): 451–462.
Published: 27 May 2010
...Rosa Zaragozá; Ana Bosch; Concha García; Juan Sandoval; Eva Serna; Luís Torres; Elena R. García-Trevijano; Juan R. Viña During mammary gland involution, different signals are required for apoptosis and tissue remodelling. To explore the role of NO in the involution of mammary tissue after lactation...
Biochem J (2009) 422 (1): 43–52.
Published: 29 July 2009
...Veronica Lopez; Shannon L. Kelleher ZnT2 (zinc transporter-2) expression is restricted to tissues with unique zinc requirements such as mammary and prostate glands. We previously determined that ZnT2 plays a major role in zinc export from mammary glands, as women with a mutation in the gene...
Includes: Supplementary data
Biochem J (2006) 395 (1): 21–30.
Published: 15 March 2006
...Hajime Nakatani; Naohito Aoki; Yoshimi Nakagawa; Shinji Jin-No; Koji Aoyama; Kenji Oshima; Sachiyo Ohira; Chihiro Sato; Daita Nadano; Tsukasa Matsuda A milk membrane glycoprotein, MFG-E8 [milk fat globule-EGF (epidermal growth factor) factor 8], is expressed abundantly in lactating mammary glands...
Biochem J (2006) 395 (1): 1–19.
Published: 15 March 2006
.... extracellular matrix (ECM) glycosaminoglycan insulin-like growth factor-I (IGF-I) insulin-like growth factor-binding protein 5 (IGFBP-5) mammary gland proteolysis The IGF (insulin-like growth factor) axis plays a crucial role in regulating cellular growth, differentiation and apoptosis [ 1 , 2...
Biochem J (2003) 372 (1): 41–52.
Published: 15 May 2003
...Benjamin MILLOT; Lluís MONTOLIU; Marie-Louise FONTAINE; Teresa MATA; Eve DEVINOY The upstream regulatory regions of the mouse and rabbit whey acidic protein (WAP) genes have been used extensively to target the efficient expression of foreign genes into the mammary gland of transgenic animals...
Biochem J (2002) 367 (1): 271–277.
Published: 01 October 2002
...Joel RYON; Lee BENDICKSON; Marit NILSEN-HAMILTON During reproduction the mass and number of cells in the uterus and the mammary gland increase rapidly and then diminish more rapidly after their reproductive functions are completed. The diminishment of tissue mass, known as involution, involves...
Biochem J (2001) 360 (1): 31–38.
Published: 08 November 2001
...B. Hwa SOHN; Hyung-Bae MOON; Tae-Yoon KIM; Han-Sung KANG; Yoon Soo BAE; Kyung-Kwang LEE; Sun Jung KIM Although interleukin-10 (IL-10) is known to contribute to inflammation and pathogenesis in mammalian organs, little is known about its precise role in the mammary gland. We found that IL-10 levels...
Biochem J (2001) 359 (3): 557–565.
Published: 25 October 2001
... genes to the mammary gland. We have shown that this region exhibits three sites hypersensitive to DNase I digestion in the lactating mammary gland, and that all three sites harbour elements which can bind to Stat5 in vitro in bandshift assays. However, not all hypersensitive regions are detected at all...
Biochem J (1999) 339 (1): 33–36.
Published: 25 March 1999
... genes in the lactating mammary gland of transgenic animals. The transgene was silent in the seventh line for an unknown reason. 1 To whom correspondence should be addressed (e-mail vilotte@biotec.jouy.inra.fr ). 15 10 1998 4 1 1999 26 1 1999 The Biochemical Society, London...