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Keywords: lysine biosynthesis
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Biochem J (2018) 475 (1): 137–150.
Published: 05 January 2018
...Serena A.J. Watkin; Jeremy R. Keown; Eric Richards; David C. Goldstone; Sean R.A. Devenish; F. Grant Pearce Dihydrodipicolinate reductase (DHDPR) catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants. In contrast with the tetrameric bacterial...
Includes: Supplementary data
Biochem J (2010) 431 (3): 401–412.
Published: 11 October 2010
...Yumewo Suzuki; Kuniko Asada; Junichi Miyazaki; Takeo Tomita; Tomohisa Kuzuyama; Makoto Nishiyama HICDH (homoisocitrate dehydrogenase), which is involved in lysine biosynthesis through α-aminoadipate, is a paralogue of IPMDH [3-IPM (3-isopropylmalate) dehydrogenase], which is involved in leucine...
Includes: Supplementary data
Biochem J (2008) 411 (2): 351–360.
Published: 27 March 2008
... of this important enzyme from the ( S )-lysine biosynthesis pathway may provide the key for the design of new antibiotics to combat tuberculosis. All DHDPS enzymes that have had both their structure solved and function confirmed are homotetramers. The three-dimensional structures of DHDPS from Escherichia coli...
Includes: Supplementary data
Biochem J (2004) 377 (3): 757–762.
Published: 01 February 2004
...Renwick C. J. DOBSON; Juliet A. GERRARD; F. Grant PEARCE DHDPS (dihydrodipicolinate synthase; EC is the enzyme that catalyses the first unique step of lysine biosynthesis in plants and micro-organisms. As such, it has attracted much attention as a target for herbicide and anti-microbial...