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Keywords: lipid metabolism
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Articles
Biochem J (2021) 478 (6): 1227–1239.
Published: 19 March 2021
...Clinton J. Kidman; Cyril D.S. Mamotte; M. Adrien Eynaud; Juliane Reinhardt; Jitraporn Vongsvivut; Mark J. Tobin; Mark J. Hackett; Ross M. Graham Hepatocytes are essential for maintaining the homeostasis of iron and lipid metabolism in mammals. Dysregulation of either iron or lipids has been linked...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2020) 477 (21): 4243–4261.
Published: 13 November 2020
...) . cholesterol glycolipid immune modulation lipid metabolism NKT cell Steryl glycosides (SGs) are derivatives of sterols (steroids with a hydroxy group at the C3 carbon in ring A of four condensed aliphatic rings) glycosylated at the hydroxy group. SG was first isolated from olives more than...
Articles
Biochem J (2020) 477 (12): 2347–2361.
Published: 26 June 2020
... 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 AMPK cardiovascular disease risk factors cholesterol synthesis inflammation lipid metabolism sodium-glucose transporter 2 inhibitors Canagliflozin is a sodium-glucose transporter 2...
Includes: Supplementary data
Articles
Biochem J (2020) 477 (7): 1261–1286.
Published: 09 April 2020
... of such tools. Correspondence: Denis P. Blondin ( denis.p.blondin@usherbrooke.ca ) 27 1 2020 13 3 2020 16 3 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 bioenergetics brown adipose tissue lipid metabolism positron...
Articles
Biochem J (2019) 476 (16): 2321–2346.
Published: 28 August 2019
... by Portland Press Limited on behalf of the Biochemical Society 2019 4-kinase Golgi apparatus lipid metabolism metastasis phosphatidylinositol PI4P Phosphoinositides, also known as inositol phospholipids or PIPs, regulate a vast array of cellular functions including receptor-mediated...
Articles
Biochem J (2019) 476 (13): 1975–1994.
Published: 15 July 2019
.... The presence of substrate channeling in fatty acid metabolism has been reported from in vivo studies [ 18 , 19 ] as well as from in vitro studies, for example for EcTFE [ 4 ] and mitochondrial (porcine) TFE [ 20 ]. Recent experimental studies on lipid metabolizing enzyme systems have suggested two...
Includes: Supplementary data
Articles
Biochem J (2019) 476 (13): 1929–1942.
Published: 09 July 2019
... 2019 11 6 2019 13 6 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 endoplasmic reticulum lipid droplets lipid metabolism organelle biogenesis plant biology triglycerides A general model for the formation...
Articles
Biochem J (2018) 475 (10): 1789–1791.
Published: 31 May 2018
...@le.ac.uk ) 24 4 2018 28 4 2018 2 5 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 lipid metabolism metabolomics obesity oxidative stress Metabolic syndrome is a multifactorial risk factor for type-2 diabetes...
Articles
Biochem J (2017) 474 (4): 557–569.
Published: 03 February 2017
... the AMPK β1β2-WT and KO mice to examine whether AMPK is required for our M-CoA sensitivity responses. AMPK CPT-I intermediate filament lipid metabolism mitochondrial respiration muscle metabolism The basic reciprocal interaction of carbohydrate and fatty acid oxidation during exercise...
Articles
Biochem J (2016) 473 (23): 4311–4325.
Published: 25 November 2016
...@berkeley.edu ) * These authors contributed equally to this work. 10 6 2016 19 9 2016 26 9 2016 26 9 2016 © 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2016 adaptation budding yeast lipid metabolism protein kinases...
Articles
Biochem J (2015) 469 (2): 189–198.
Published: 06 July 2015
... and function. acyl-CoA-binding domain containing 3 (ACBD3) lipid metabolism nicotinamide adenine dinucleotide (NAD + ) metabolism poly(ADP-ribose) polymerase 1 (PARP1) poly(ADP-ribosyl)ation (PARylation) 1 To whom correspondence should be addressed (email sangwonk@mail.med.upenn.edu...
Includes: Supplementary data
Articles
Biochem J (2014) 459 (1): 137–147.
Published: 14 March 2014
...-accumulating factor in insect fluid. Bombyx mori humoral factor insect lipid metabolism Niemann–Pick disease type C2 (NPC2) triglyceride (triacylglycerol) Lipid metabolism is regulated by factors in the blood or body fluids in connection with food consumption and developmental stage...
Includes: Supplementary data
Articles
Biochem J (2013) 455 (1): 119–130.
Published: 13 September 2013
...Rajesh K. Harijan; Tiila R. Kiema; Mikael P. Karjalainen; Neelanjana Janardan; M. R. N. Murthy; Manfred S. Weiss; Paul A. M. Michels; Rik K. Wierenga Thiolases are essential CoA-dependent enzymes in lipid metabolism. In the present study we report the crystal structures of trypanosomal...
Includes: Supplementary data
Articles
Biochem J (2008) 413 (1): e5–e6.
Published: 12 June 2008
... it was synthesized. 1 email nielsene@umich.edu 15 5 2008 27 5 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 lipid metabolism lipid pools PtdIns PtdIns synthase (PIS) A typical eukaryotic cell contains a myriad of distinct membrane types, each...
Articles
Biochem J (2008) 413 (1): 115–124.
Published: 12 June 2008
... and immediate metabolic context of the biosynthetic enzymes. 1 To whom correspondence should be addressed (email iheilma@uni-goettingen.de ). 8 10 2007 10 3 2008 10 4 2008 10 4 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 lipid metabolism...
Includes: Supplementary data
Articles
Biochem J (2007) 405 (2): 319–329.
Published: 27 June 2007
... t.k.smith@dundee.ac.uk ). 5 2 2007 26 3 2007 3 4 2007 3 4 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 interfacial activation lipid metabolism lysophosphatidylcholine phospholipase Trypanosoma brucei All eukaryotic organisms...
Articles
Biochem J (2005) 389 (2): 249–257.
Published: 05 July 2005
... [ 73 ]. This protein is able to bind to cells and to potentiate the pulses of the aggregation trigger cAMP [ 74 ]. antimicrobial activity innate immunity lipid metabolism lipid-binding membrane interaction saposin-like protein The primary goal of genome sequencing projects...
Articles
Biochem J (2005) 389 (1): 47–56.
Published: 21 June 2005
... 3 2005 11 3 2005 11 3 2005 The Biochemical Society, London 2005 brown fat CCAAT/enhancer-binding protein β (C/EBPβ) lipid metabolism lipoprotein lipase peroxisome-proliferator-activated receptor γ co-activator 1α (PGC-1α) uncoupling protein (UCP) C/EBPs (CCAAT...
Articles
Biochem J (2004) 382 (1): 93–100.
Published: 10 August 2004
... recommended by the manufacturer. The blot was washed at high stringency (0.1×SSC/0.1% SDS at 60 °C), and labelled bands were visualized by autoradiography. cholesterol ecdysone lipid metabolism prothoracic glands steroid The cDNA containing the entire open reading frame was amplified by PCR...
Articles
Biochem J (2002) 368 (3): 679–682.
Published: 15 December 2002
... Society, London ©2002 2002 ACBP acyl-CoA esters lipid metabolism small interference RNA (siRNA) Abbreviations used: ACBP, acyl-CoA binding protein; Acb1p, the yeast homologue of ACBP; EST, expressed sequence tag; PARP, poly(ADP-ribose) polymerase; siRNA, small interference RNA...
Articles
Biochem J (2002) 367 (2): 433–441.
Published: 15 October 2002
..., (ii) stabilization of the dehydrogenation domains by interaction with the domain D and (iii) the targeting of the perMFE-1 to peroxisomes via its C-terminal tripeptide. Key words: b-oxidation, lipid metabolism, peroxisome, protein engineering, structure function. strategy of an oxyanion intermediate...
Articles
Biochem J (2002) 366 (1): 23–34.
Published: 15 August 2002
..., the regulation of SM biosynthesis or its intracellular trafficking. Key words: lipid metabolism, lipid transport proteins, lipid traffic, phosphatidylcholine. enzyme of theCDP-choline pathway. In Šitro experiments showed that Sec14p inhibits this enzyme only when it binds a PC molecule [8]. Therefore Sec14p...
Articles
Biochem J (2002) 363 (3): 483–491.
Published: 24 April 2002
... of eukaryotic cells. Key words: catalase, lipid metabolism, oxidative stress, peroxi- some proliferation, redox regulation. Peroxisome-derived oxidative stress has long been under debate in mediating at least some of the consequences of peroxisomal proliferation [11,12]. Peroxisomes have been char- acterized...
Articles
Biochem J (2001) 357 (1): 183–193.
Published: 25 June 2001
..., GenBank® and GSDB Nucleotide Sequence Databases under the accession number AF320307. 28 2 2001 2 4 2001 10 5 2001 The Biochemical Society, London ©2001 2001 lipid metabolism monosaturated fatty acids palmitoleate transcription Abbreviations used: AP-2, activator...
Articles
Biochem J (2001) 353 (2): 231–238.
Published: 08 January 2001
... and PPARc. Key words: antagonist, lipid metabolism, nuclear receptor. In the present study we performed a competition binding assay with the soluble LBD proteins of PPARa and PPARc and [$H]KRP-297, a known dual agonist for these receptors [21]. We found that fatty-acyl-CoAs interact directly with the LBDs...
Articles
Biochem J (1999) 342 (1): 179–187.
Published: 10 August 1999
...-likesequencecomparedwith sixteen for the human pancreatic BSDL. The actual intracellular function of this human BSDL hepatoma isoform remains to be elucidated. Key words: cancer, lipid metabolism, liver. ation. Putative sites for O-glycosylation are located within the C- terminal domain of the protein, which...
Articles
Biochem J (1999) 341 (2): 347–354.
Published: 08 July 1999
... 1999 The Biochemical Society, London © 1999 1999 fatty-acid metabolism lipid metabolism heart Biochem. J. (1999) 341, 347 354 (Printed in Great Britain) 347 Multiple-site phosphorylation of the 280 kDa isoform of acetyl-CoA carboxylase in rat cardiac myocytes : evidence that cAMP...
Articles
Biochem J (1999) 340 (1): 255–264.
Published: 10 May 1999
... and in the generation of alternative transcripts, suggesting a species-specific component of SCD regulation and function. Key words: enzymes, Homo sapiens, lipid metabolism, mono- saturated fatty acid, oleic acid. frame encoding a 41.4 kDa protein [29]. The mRNA contains an unusually long 3«-untranslated region of 3.5...