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Keywords: intrinsically disordered proteins
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Biochem J (2021) 478 (15): 3015–3024.
Published: 10 August 2021
...Vladimir N. Uversky This perspective article describes some of the key points of my personal journey through the intriguing world of intrinsically disordered proteins (IDPs). It also shows the evolution of my perception of functional proteins from a standard lock-and-key theory, where a unique...
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Biochem J (2021) 478 (11): 2035–2050.
Published: 08 June 2021
...Kaare Teilum; Johan G. Olsen; Birthe B. Kragelund With the increased focus on intrinsically disordered proteins (IDPs) and their large interactomes, the question about their specificity — or more so on their multispecificity — arise. Here we recapitulate how specificity and multispecificity...
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Biochem J (2017) 474 (21): 3689–3704.
Published: 25 October 2017
... the complex. A discussion of how this bipartite interaction between PPIH and PRPF4 may modulate spliceosomal function is included. immunophilins intrinsically disordered proteins protein–protein interactions spliceosomes 5000× SYPRO Orange (Sigma) was diluted to 200× in gel filtration buffer...
Includes: Supplementary data
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Biochem J (2017) 474 (15): 2509–2532.
Published: 12 July 2017
... 19 4 2017 5 5 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 binding mechanisms gene regulatory networks intrinsically disordered proteins molecular interactions transcription factors Composite molecular networks...