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Keywords: histones
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Biochem J (2023) 480 (9): 629–647.
Published: 10 May 2023
... a specific combinatorial histone signature of H3K4me0/H3K23ac via its C-terminal plant homeodomain (PHD) and bromodomain (Bromo). Aberrant expression of TRIM24 positively correlates with H3K23ac levels, and high levels of both TRIM24 and H3K23ac predict poor survival of breast cancer patients. Little has...
Includes: Supplementary data
Biochem J (2023) 480 (1): 57–85.
Published: 11 January 2023
... to changes in epigenetic marks, such as histone post-translational modifications (PTMs), DNA methylation and chromatin accessibility to regulate gene expression. Crosstalk between different epigenetic mechanisms, such as that between histone PTMs and DNA methylation, leads to an intricate network...
Biochem J (2021) 478 (3): 511–532.
Published: 10 February 2021
...Bethany C. Taylor; Nicolas L. Young Histones are essential proteins that package the eukaryotic genome into its physiological state of nucleosomes, chromatin, and chromosomes. Post-translational modifications (PTMs) of histones are crucial to both the dynamic and persistent regulation of the genome...
Biochem J (2020) 477 (17): 3367–3386.
Published: 17 September 2020
...Yan Huang; Yaxin Dai; Zheng Zhou Histone chaperones include a wide variety of proteins which associate with histones and regulate chromatin structure. The classic H2A–H2B type of histone chaperones, and the chromatin remodeling complex components possessing H2A–H2B chaperone activity, show a broad...
Biochem J (2020) 477 (16): 2971–2980.
Published: 21 August 2020
...Sarah A. Mann; Megan K. DeMart; Braidy May; Corey P. Causey; Bryan Knuckley Methylation of arginine residues occurs on a number of protein substrates, most notably the N-terminal tails of histones, and is catalyzed by a family of enzymes called the protein arginine methyltransferases (PRMTs...
Includes: Supplementary data