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Keywords: glycogen synthase kinase 3 (GSK3)
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Biochem J (2014) 464 (1): 145–156.
Published: 23 October 2014
...James W. Robinson; Iryna Leshchyns’ka; Hovik Farghaian; William E. Hughes; Vladimir Sytnyk; Graham G. Neely; Adam R. Cole Glycogen synthase kinase 3 (GSK3) is essential for normal development and function of the central nervous system. It is especially important for regulating neurotransmission...
Biochem J (2013) 452 (1): 131–137.
Published: 25 April 2013
... glycogen synthase kinase 3 (GSK3) protein kinase CK1 pyrvinium pamoate Wnt signalling Nearly all aspects of life are controlled by protein phosphorylation, catalysed by protein kinases which give rise to a complex and integrated network of signalling pathways. The first-choice strategy...
Includes: Supplementary data
Biochem J (2012) 447 (1): 137–147.
Published: 12 September 2012
... synthase kinase 3 (GSK3) mammalian target of rapamycin (mTOR) proline-rich Akt substrate of 40 kDa (PRAS40) PKB (protein kinase B), also known as Akt, a serine/threonine kinase, is a key mediator of insulin and growth factor signalling downstream of PI3K (phosphoinositide 3-kinase). PKB regulates...
Includes: Supplementary data
Biochem J (2012) 441 (1): 227–236.
Published: 14 December 2011
... ]. The identities and differences in the amino acid sequences of RASSF1A and RASSF1C indicate they may have different physiological and pathological functions. DNA damage glycogen synthase kinase 3 (GSK3) phosphoinositide 3-kinase (PI3K) stability Ras association (RalGDS/AF-6) domain family member 1C...
Includes: Supplementary data
Biochem J (2006) 393 (1): 1–6.
Published: 12 December 2005
... related in structure and have similar specificity determinants. 1 To whom correspondence should be addressed (email p.cohen@dundee.ac.uk ). 20 9 2005 7 10 2005 11 10 2005 The Biochemical Society, London 2006 glycogen synthase kinase 3 (GSK3) kinase substrate tracking...
Biochem J (2005) 391 (2): 359–370.
Published: 10 October 2005
... reported that PP1 (serine/threonine protein phosphatase type-1) associates with FAK at this time and dephosphorylates it [ 8 ]. On the other hand, no PP1 was found to associate with mitotic FAK [ 8 ]. cell adhesion cell migration focal adhesion kinase (FAK) glycogen synthase kinase 3 (GSK3...
Biochem J (2004) 384 (3): 477–488.
Published: 07 December 2004
... 4 10 2004 The Biochemical Society, London 2004 glycogen synthase kinase 3 (GSK3) n-myc downstream-regulated gene (NDRG) p53 phosphorylation serum- and glucocorticoid-induced kinase 1 (SGK1) SGK1 is a member of the AGC subfamily of protein kinases and most closely...
Biochem J (2003) 372 (1): 1–13.
Published: 15 May 2003
... of positive and negative MAPK regulators. In the case of glycogen synthase kinase 3 (GSK3), the presence of a phosphate-binding site allows docking of previously phosphorylated (primed) substrates; this docking site is also required for the mechanism of GSK3 inhibition by phosphorylation. In contrast, non...