1-15 of 15
Keywords: focal adhesion
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2019) 476 (11): 1585–1604.
Published: 11 June 2019
... potential, and low numbers. The key transcription regulators of mitochondrial biogenesis also decreased. These results indicate that mitochondrial dysfunction leads to an inability to support the pluripotency maintenance. Moreover, down-regulated glutathione metabolism and up-regulated focal adhesion...
Includes: Supplementary data
Articles
Articles
Biochem J (2015) 465 (3): 383–393.
Published: 22 January 2015
.... Cells expressing a mutant vinculin deficient in actin binding and bundling display migration and traction force defects. Vinculin binding to actin is critical for cell migration and force generation. actin adhesion focal adhesion force vinculin Cell migration is a complex process...
Articles
Biochem J (2014) 464 (1): 99–108.
Published: 23 October 2014
... cell attachment to fibronectin recruits MEKK2 to focal adhesion complexes, and that MEKK2 knockdown is associated with stabilized focal adhesions and significant inhibition of tumour cell migration. In the present study we investigate MEKK2 function in focal adhesions and we report that MEKK2...
Includes: Supplementary data
Articles
Biochem J (2014) 462 (2): 199–213.
Published: 07 August 2014
... microdomains of cAMP and Ca 2+ . Exploration of the regulation of susceptible ACs by Ca 2+ in vitro is relatively straightforward, although it does reveal features that are exploited in vivo . adenylate cyclase A-kinase-anchoring protein (AKAP) focal adhesion microdomain protein kinase scaffold...
Articles
Articles
Biochem J (2013) 454 (1): 13–30.
Published: 26 July 2013
... as with focal adhesions and cell junctions, and are probably involved in cell migration, polarity and proliferation. Finally, we consider the association of GCKIIIs with a number of human diseases, particularly cerebral cavernous malformations. 1 Correspondence may be addressed to either of these authors...
Includes: Multimedia, Supplementary data
Articles
Articles
Articles
Biochem J (2008) 409 (3): 657–667.
Published: 15 January 2008
... with vinculin in vivo , and this association is promoted by PtdIns(4,5) P 2 . SNTIII also specifically co-localizes with vinculin within focal adhesions when transiently expressed in mammalian cells. In contrast, other regions of synemin show distinct localization patterns in comparison with those of SNTIII...
Articles
Biochem J (2008) 409 (3): e1–e2.
Published: 15 January 2008
... of the type IV intermediate filament protein synemin interacts directly with the focal adhesion protein vinculin in its active state. Interaction of adhesion components with intermediate filaments could serve as a general mechanism to regulate cell- and tissue-specific cytoskeleton-membrane attachment...
Articles
Biochem J (2005) 388 (2): 631–638.
Published: 24 May 2005
...: the potential tumour suppressor Tes, an actin-binding protein mainly located at focal adhesions; and EVL (Ena/vasodilator-stimulated phosphoprotein-like protein), another actin-binding protein, equally recruited at focal adhesions. Interactions between spectrin and overexpressed Tes and EVL were confirmed by co...
Articles
Biochem J (2004) 378 (3): 1067–1072.
Published: 15 March 2004
... 12 12 2003 The Biochemical Society, London ©2004 2004 α-actinin actin bundling cytoskeleton focal adhesion phosphoinositide protein flexibility Abbreviations used: CH, calponin homology; GST, glutathione S-transferase. Biochem. J. (2004) 378, 1067 1072 (Printed in Great...
Articles
Biochem J (2001) 356 (3): 737–745.
Published: 08 June 2001
... myogenic cells identified by bromodeoxyuridine and desmin double labelling in knockout mice on the first 2 days after injury. Expression of INTRODUCTION Focal adhesions are specialized cell-substratum junctions that are present in cells attaching to extracellular matrix. They are formed around...
Articles
Biochem J (2000) 351 (2): 403–411.
Published: 10 October 2000
...Huaiyang CHEN; Akiko ISHII; Wai-Keung WONG; Lan Bo CHEN; Su Hao LO Tensin is a focal-adhesion molecule that binds to actin filaments and interacts with phosphotyrosine-containing proteins. To analyse tensin's function in mammals, we have cloned tensin cDNAs from human and cow. The isolated approx...