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Keywords: farnesoid X receptor (FXR)
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Biochem J (2013) 454 (2): 267–274.
Published: 09 August 2013
...) farnesoid X receptor (FXR) hepatocyte phosphatidic acid Bile acids are amphipathic molecules that regulate the elimination of cholesterol. In humans there are two major bile acid biosynthetic pathways, neutral and acidic, that are initiated by cholesterol 7α-hydroxylase (CYP7A1) and mitochondrial...
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Biochem J (2011) 438 (2): 315–323.
Published: 12 August 2011
... involving members of the nuclear receptor superfamily [ 6 ], counteract the detrimental actions of excess bile acids on GI organs. bile acid chenodeoxycholic acid (CDCA) farnesoid X receptor (FXR) keratin gastric cancer stomach AGS/FXR and AGS/EV cells were treated for 16 h with 100 μM...
Includes: Supplementary data
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Biochem J (2004) 382 (3): 913–921.
Published: 07 September 2004
... 2004 17 6 2004 The Biochemical Society, London 2004 bile acid farnesoid X receptor (FXR) fasting nuclear receptor peroxisome-proliferator-activated receptor-γ co-activator-1α (PGC-1α) transcriptional co-activator The plasmids pCMX-flag-mPGC-1α, pCMX-flag-mPGC-1β...