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Keywords: down-regulation
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Biochem J (2005) 389 (2): 465–469.
Published: 05 July 2005
... of cells. On ephrinB1 stimulation, the small GTPases Rho and Ras are activated and Rap1 is inactivated. Importantly, when a constitutively active Rap1 mutant was introduced into these cells, ephrinB1-induced retraction was inhibited. From these results, we conclude that down-regulation of Rap1...
Biochem J (2002) 368 (1): 349–355.
Published: 15 November 2002
...Jyoti SRIVASTAVA; Katarzyna J. PROCYK; Xavier ITURRIOZ; Peter J. PARKER Classical and novel protein kinase C (PKC) isoforms are down-regulated as a result of chronic activation by certain tumour promoters and physiological stimuli; however, the mechanisms leading to down-regulation are not fully...
Biochem J (1999) 342 (2): 387–395.
Published: 24 August 1999
...), down-regulation (24 h), inhibition of forskolin-stimulated cAMP accumulation, or activation of co-transfected G-protein-activated inward rectifier K + /cardiac inward rectifying K + (GIRK1/CIR K + ) channels. Also unaffected by palmitoylation is guanosine 5′-[γ-thio]-triphosphate ([S]GTP)-sensitive...