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Keywords: cystic fibrosis transmembrane conductance regulator
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Biochem J (2021) 478 (20): 3741–3756.
Published: 21 October 2021
...Monali NandyMazumdar; Alekh Paranjapye; James Browne; Shiyi Yin; Shih-Hsing Leir; Ann Harris The cystic fibrosis transmembrane conductance regulator ( CFTR ) gene lies within a topologically associated domain (TAD) in which multiple cis -regulatory elements (CREs) and transcription factors (TFs...
Includes: Supplementary data
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Biochem J (2018) 475 (7): 1323–1334.
Published: 16 April 2018
...Michael J. Mutolo; Shih-Hsing Leir; Sara L. Fossum; James A. Browne; Ann Harris Mutations in the cystic fibrosis transmembrane conductance regulator ( CFTR ) gene cause the inherited disorder cystic fibrosis (CF). Lung disease is the major cause of CF morbidity, though CFTR expression levels...
Includes: Supplementary data
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Biochem J (2004) 380 (1): 67–74.
Published: 15 May 2004
... regulatory gene, cftr . However, higher GSNO levels prevented Sp3 binding, augmented Sp1 binding and prevented both cftr transcription and CFTR (cystic fibrosis transmembrane conductance regulator) expression. We conclude that low concentrations of GSNO favour Sp3 binding to ‘housekeeping’ genes such as cftr...
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Biochem J (2002) 364 (1): 115–120.
Published: 08 May 2002
... in CF. 1 To whom correspondence should be addressed (e-mail Charles.Falany@ccc.uab.edu ). 11 7 2001 7 2 2002 2 3 2002 The Biochemical Society, London ©2002 2002 cystic fibrosis transmembrane conductance regulator β-oestradiol knock-out mice dehydroepiandrosterone...