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Keywords: co-activator
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Biochem J (2014) 461 (1): 15–32.
Published: 13 June 2014
... of the versatility and utility of WT1 as a master regulator of organ development, a tumour suppressor and an oncogene. 3 12 2013 10 4 2014 24 4 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 co-activator co-repressor promoter transcription Wilms’ tumour 1 (WT1...
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Biochem J (2013) 453 (1): 49–60.
Published: 13 June 2013
... (steroid receptor co-activator 1), but not by PCAF (p300/CBP-associated factor) and PGC-1α (PPAR co-activator 1α). The physical interaction between lipin1 and PPARγ occurs at the lipin1 C-terminal region from residues 825 to 926, and the VXXLL motif at residue 885 is critical for binding...
Includes: Supplementary data
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Biochem J (2012) 447 (3): 437–447.
Published: 05 October 2012
...Geun Hyang Kim; Kyung Jin Lee; Gyun-Sik Oh; Jin Yoon; Hae Won Kim; Seung-Whan Kim ASC-2 (activating signal co-integrator-2, also known as AIB3 and NCoA6) is a transcriptional co-activator and regulates insulin secretion and β-cell survival. The present study was performed to elucidate the role...
Includes: Supplementary data
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Biochem J (2005) 386 (1): E1.
Published: 08 February 2005
... the p300 transcriptional co-activator and is required for Smad3-dependent transcriptional activation. This study raises interesting questions about the nature and regulation of Smad-regulated gene activation and elevates the status of the linker domain to rival that of the much-lauded MH1 and MH2 domains...
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Biochem J (2004) 382 (1): 323–329.
Published: 10 August 2004
...Min LI; Padmavathy NAIDU; Yihong YU; Nathan A. BERGER; Perry KANNAN Poly(ADP-ribose) polymerase-1 (PARP-1) is a co-activator for AP-2α (activator protein 2α)-mediated transcriptional activation. In the present study, we find that the role of PARP-1 in AP-2α transcription is distinctly dualistic...
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Biochem J (2004) 381 (1): 267–273.
Published: 22 June 2004
... or lack of involucrin expression. Recently, a dominant-negative construct of the transcriptional co-activator P/CAF [p300/CBP-associated factor, where CBP stands for CREB (cAMP-response-element-binding protein)-binding protein] was shown to inhibit involucrin expression in immortalized keratinocytes...
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Biochem J (2003) 376 (2): 465–472.
Published: 01 December 2003
... and chlorpromazine. Also, the induction of CYP2B10 mRNA by oestrogens was less pronounced in mouse primary hepatocytes. Yeast two-hybrid assays indicated that, unlike androstenol and the established activators, oestrogens attracted both nuclear receptor co-repressors and co-activators to the mCAR ligand-binding...
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