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Keywords: cefotaxime
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Biochem J (2018) 475 (1): 273–288.
Published: 11 January 2018
... of the substitutions (P225S and D222N) are largely responsible for the observed alteration of kinetic parameters, while the third (S109L) may serve to stabilize the protein. Structures of OXA-239 with cefotaxime, doripenem and imipenem bound as acyl-intermediates were determined. These structures reveal that OXA-239...
Includes: Supplementary data