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Keywords: bile
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Articles

Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice

Tineke KOK, Vincent W. BLOKS, Henk WOLTERS, Rick HAVINGA, Peter L.M. JANSEN, Bart STAELS, Folkert KUIPERS
Journal: Biochemical Journal
Biochem J (2003) 369 (3): 539–547.
https://doi.org/10.1042/bj20020981
Published: 01 February 2003
... fibrates. Fibrates induce the hepatic expression of murine multidrug resistance 2 ( Mdr2 ), encoding the canalicular phospholipid translocator. The physiological role of PPARα in regulation of Mdr2 and other genes involved in bile formation is unknown. We found no differences in hepatic expression...
View article titled, Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice
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Articles

Polarized cholesterol and phospholipid efflux in cultured gall-bladder epithelial cells: evidence for an ABCA1-mediated pathway

Jin LEE, Andrew SHIRK, John F. ORAM, Sum P. LEE, Rahul KUVER
Journal: Biochemical Journal
Biochem J (2002) 364 (2): 475–484.
https://doi.org/10.1042/bj20011493
Published: 01 June 2002
...Jin LEE; Andrew SHIRK; John F. ORAM; Sum P. LEE; Rahul KUVER Gall-bladder epithelial cells (GBEC) are exposed to high concentrations of cholesterol in bile. Whereas cholesterol absorption by GBEC is established, the fate of this absorbed cholesterol is not known. The aim of this study...
View article titled, Polarized cholesterol and phospholipid efflux in cultured gall-bladder epithelial cells: evidence for an ABCA1-mediated pathway
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Articles

Partial replacement of bile salts causes marked changes of cholesterol crystallization in supersaturated model bile systems

Tomoji NISHIOKA, Susumu TAZUMA, Gunji YAMASHITA, Goro KAJIYAMA
Journal: Biochemical Journal
Biochem J (1999) 340 (2): 445–451.
https://doi.org/10.1042/bj3400445
Published: 25 May 1999
...Tomoji NISHIOKA; Susumu TAZUMA; Gunji YAMASHITA; Goro KAJIYAMA Cholesterol crystallization is a key step in gallstone formation and is influenced by numerous factors. Human bile contains various bile salts having different hydrophobicity and micelle-forming capacities, but the importance of lipid...
View article titled, Partial replacement of <span class="search-highlight">bile</span> salts causes marked changes of cholesterol crystallization in supersaturated model <span class="search-highlight">bile</span> systems
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Articles

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

Coen C. PAULUSMA, Michael A. van GEER, Raymond EVERS, Marc HEIJN, Roelof OTTENHOFF, Piet BORST, Ronald P. J. OUDE ELFERINK
Journal: Biochemical Journal
Biochem J (1999) 338 (2): 393–401.
https://doi.org/10.1042/bj3380393
Published: 22 February 1999
...Coen C. PAULUSMA; Michael A. van GEER; Raymond EVERS; Marc HEIJN; Roelof OTTENHOFF; Piet BORST; Ronald P. J. OUDE ELFERINK The canalicular multispecific organic anion transporter (cMOAT), a member of the ATP-binding cassette transporter family, mediates the transport of a broad range of non-bile...
View article titled, Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
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