1-21 of 21
Keywords: X-ray structure
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Articles
Biochem J (2020) 477 (1): 275–284.
Published: 17 January 2020
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . GCN2 kinase x-ray structure GCN2, general control nonderepressible 2 kinase, is one of four known vertebrate...
Includes: Supplementary data
Articles
Biochem J (2017) 474 (15): 2601–2617.
Published: 21 July 2017
... replacement, using as a search model PDB ID: 3UF2. A summary of the diffraction data collection statistics is given in Supplementary Table S1. Figure 1. Structure of the M-CSF C31S mutant, compared with the M-CSF wild-type structure. ( A ) X-ray structure of the dimeric M-CSF C31S mutant solved here...
Includes: Supplementary data
Articles
Articles
Biochem J (2016) 473 (10): 1329–1341.
Published: 11 May 2016
..., an enzyme that contributes to progression and metastasis of lung, prostate, breast and pancreatic cancers. cancer therapy directed evolution enzyme inhibition mesotrypsin protease inhibitor protein engineering proteolysis X-ray structure APPI M17G/I18F/F34V was mixed with catalytically...
Includes: Supplementary data
Articles
Articles
Articles
Biochem J (2014) 458 (3): 525–536.
Published: 28 February 2014
... ]. conformational dynamics FK506-binding protein 12 (FKBP12) linebroadening analysis NMR slow exchange X-ray structure The peptide prolyl isomerase FKBP12 (FK506-binding protein 12) was initially characterized for its role in binding the immunosuppressants FK506 and rapamycin. The ternary complex...
Includes: Supplementary data
Articles
Biochem J (2013) 456 (1): 81–88.
Published: 24 October 2013
... and closed conformations and probe the reaction mechanism through the binding of transition state mimics. We confirm that the nucleophilic attack occurs on the β-phosphate. deoxyuridine triphosphate nucleotidohydrolase (dUTPase) mechanism nucleotide binding Trypanosoma X-ray structure...
Includes: Supplementary data
Articles
Articles
Biochem J (2013) 453 (3): 371–380.
Published: 12 July 2013
... isomerization. Many of the residues exhibiting resonance doubling also participate in conformational line-broadening transition(s) that occur ~10 5 -fold more rapidly, proposed previously to arise from a single global process. The 1.70 Å (1 Å=0.1 nm) resolution X-ray structure of the H87V variant is strikingly...
Articles
Biochem J (2013) 449 (1): 51–60.
Published: 07 December 2012
... acid–histidine–water triad X-ray structure OADs [OAA (oxaloacetate) decarboxylase; EC 4.1.1.3] catalyse the decarboxylation of OAA to pyruvate and CO 2 . There are two subfamilies: the membrane-bound OAD sodium pump subfamily [ 1 ] and the cytosolic soluble OAD subfamily. The membrane-bound...
Includes: Supplementary data
Articles
Biochem J (2012) 445 (2): 175–182.
Published: 27 June 2012
...Winfried Meining; Arne Skerra We describe the 2.3 Å (1 Å=0.1 nm) X-ray structure of α 1 m (α 1 -microglobulin), an abundant protein in human blood plasma, which reveals the β-barrel fold typical for lipocalins with a deep pocket lined by four loops at its open rim. Loop #1 harbours the residue Cys...
Includes: Supplementary data
Articles
Biochem J (2012) 442 (3): 483–494.
Published: 24 February 2012
... software 2.0.3 and a 1:1 Langmuir model for fittings. Fab fragment human hepsin antibody induced conformational change prostate cancer transmembrane serine protease X-ray structure Hepsin belongs to the type II transmembrane serine protease family, and is expressed in several human...
Includes: Supplementary data
Articles
Biochem J (2009) 420 (1): 17–25.
Published: 28 April 2009
... and particularly in the vicinity of the 29-residue insert in the human enzyme sequence, a confident prediction of the functional consequences of mutations was not possible. In this paper, we present the X-ray structure of the R167Q mutant of human uPBGD. This was one of the first PBGD mutations...
Includes: Supplementary data
Articles
Articles
Articles
Articles
Articles
Articles