... for growth of S. Typhimurium in M9 minimal medium, in tissue cultured cells, and in mice. Studies to resolve which of the three known functions of Pfs were key to murine virulence suggested that downstream production of autoinducer-2, spermidine and methylthioribose were non-essential for Salmonella...

.... The open structural model of σ S from Salmonella described in Monteil et al. [ 11 ] was used and is similar to the recently released structure of E. coli σ S in Eσ S [ 9 ]. The closed conformation of σ S was initially generated using as a template the structure of σ 28 in the σ 28 –FlgM complex...

... global gene transcription in stationary phase and under stress conditions. The small regulatory protein Crl stimulates the association of σ S with the core RNAP in Escherichia coli and Salmonella enterica serovar Typhimurium, through direct and specific interaction with σ S . The structural determinants...

...Maud E. S. Achard; Kaiwen W. Chen; Matthew J. Sweet; Rebecca E. Watts; Kate Schroder; Mark A. Schembri; Alastair G. McEwan Iron acquisition is an important aspect of the host–pathogen interaction. In the case of Salmonella it is established that catecholate siderophores are important for full...

.../caspase 1 foci. The lack of foci formation for ASC CARD mutants correlates with a loss of IL-1β (interleukin 1β) processing in response to NLRP (NLR family, PYD domain-containing) 3 or AIM2 agonists in RAW264.7 cell reconstitution assays. Analogously, we show that productive formation of the Salmonella...

.... The present study investigated the role of copper in mouse macrophage responses to Salmonella enterica sv. Typhimurium. The copper chelator BCS (bathocuproinedisulfonic acid, disodium salt) increased intracellular survival of S . Typhimurium within primary mouse BMM (bone-marrow-derived macrophages) at 24 h...

... Salmonella Typhimurium. The ZraP chaperone mechanism is catalytic and independent of ATP; the chaperone activity is dependent on the presence of zinc, which is shown to be responsible for the stabilization of an oligomeric ZraP complex. Furthermore, ZraP can act to repress the two-component regulatory system...

... gas nitrous oxide (N 2 O) is linked with anoxic nitrate catabolism by Salmonella enterica serovar Typhimurium. Salmonella can synthesize two types of nitrate reductase: a membrane-bound form (Nar) and a periplasmic form (Nap). Nitrate catabolism was studied under nitrate-rich and nitrate-limited...

...Hugh Kim; Colin D. White; Zhigang Li; David B. Sacks Salmonella enterica serotype Typhimurium invades eukaryotic cells by re-arranging the host-cell cytoskeleton. However, the precise mechanisms by which Salmonella induces cytoskeletal changes remain undefined. IQGAP1 (IQ motif-containing GTPase...

... in available databases indicates that the same signal for lipid modification is also present in the sodC gene products from other mycobacteria and Gram-positive bacteria and, uniquely, in two distinct sodC gene products from the Gram-negative bacterium Salmonella typhimurium . Evidence is also provided...