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Keywords: STAT3
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Biochem J (2022) 479 (9): 995–1006.
Published: 12 May 2022
... The Author(s) 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . binucleate cathepsins cell death lineage mammary gland STAT3 The mammary gland...
Biochem J (2016) 473 (19): 3205–3219.
Published: 27 September 2016
...Elena Butturini; Giovanni Gotte; Daniele Dell'Orco; Giulia Chiavegato; Valerio Marino; Diana Canetti; Flora Cozzolino; Maria Monti; Piero Pucci; Sofia Mariotto Signal transducer and activator of transcription 3 (STAT3) is a transcription factor activated by the phosphorylation of tyrosine 705...
Includes: Supplementary data
Biochem J (2015) 466 (2): 291–298.
Published: 20 February 2015
...Wei Ma; Gloria Fuentes; Xiaohe Shi; Chandra Verma; George K. Radda; Weiping Han FoxO1, which is up-regulated during early stages of diet-induced leptin resistance, directly interacts with STAT3 and prevents STAT3 from binding to specificity protein 1 (SP1)–pro-opiomelanocortin (POMC) promoter...
Includes: Supplementary data
Biochem J (2015) 465 (2): 295–303.
Published: 06 January 2015
... of the transcription factor STAT3 (signal transducer and activator of transcription 3) and up-regulated SMAD7 expression while down-regulating expression of SMAD4. Consequently, CD4 + T-cells were desensitized to transforming growth factor (TGF) β1, a cytokine employed by Tregs to exert a broad inhibitory function...
Includes: Supplementary data
Biochem J (2005) 392 (2): 335–344.
Published: 22 November 2005
...Sujoy Bhattacharya; Ramesh M. Ray; Leonard R. Johnson Activation of STAT3 (signal transducer and activator of transcription 3) plays a crucial role in cell survival and proliferation. The aim of the present study was to clarify the role of STAT3 signalling in the protection of polyamine-depleted...
Biochem J (2003) 376 (2): 457–464.
Published: 01 December 2003
... be activated by EGF in certain cell types. Since Ras-MAPK and STAT pathways are simultaneously stimulated by EGF, and Tyr-1086 and Tyr-1068 of EGFR are reported to be the binding sites for both Grb2 and Stat3, we investigated the possible regulatory role of Grb2 in STAT activation. In the present study, we...
Biochem J (2000) 351 (1): 257–264.
Published: 26 September 2000
... of transcription (STAT) pathway in endothelial signal transduction through the BK B2 receptor (B2R). In cultured bovine aortic endothelial cells (BAECs), BK activates Tyk2 of the JAK family of tyrosine kinases. Activation results in the tyrosine phosphorylation and subsequent nuclear translocation of STAT3. BK...
Biochem J (1999) 342 (2): 301–308.
Published: 24 August 1999
... of the transcription factor, Stat3, evoked by CNTF. 1 To whom correspondence should be addressed ( berse@bu.edu ). 1 3 1999 24 5 1999 15 6 1999 The Biochemical Society, London © 1999 1999 acetylcholine choline acetyltransferase mitogen-activated protein kinase Stat3 vesicular...