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Keywords: RAS proteins
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Biochem J (2023) 480 (1): 1–23.
Published: 06 January 2023
...Walter Kolch; Dénes Berta; Edina Rosta RAS proteins regulate most aspects of cellular physiology. They are mutated in 30% of human cancers and 4% of developmental disorders termed Rasopathies. They cycle between active GTP-bound and inactive GDP-bound states. When active, they can interact...