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Keywords: PD98059
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Articles
Maria Isabel Cerezo-Guisado, Natalia GarcíA-Román, Luis Jesús García-MaríN, Alberto Álvarez-Barrientos, Maria Julia Bragado, Maria Jesús Lorenzo
Journal:
Biochemical Journal
Biochem J (2007) 401 (1): 175–183.
Published: 11 December 2006
...-activated protein kinase)/ERK kinase] inhibitors, PD98059 and PD184352, were poor inducers of apoptosis in serum-treated neuroblasts. However, these inhibitors significantly increased apop-tosis induced by lovastatin treatment. Furthermore, we showed that pharmacological inhibition of both MEK...
Articles
Flavio FLAMIGNI, Annalisa FACCHINI, Cristina CAPANNI, Claudio STEFANELLI, Benedetta TANTINI, Claudio M. CALDARERA
Journal:
Biochemical Journal
Biochem J (1999) 341 (2): 363–369.
Published: 08 July 1999
...Flavio FLAMIGNI; Annalisa FACCHINI; Cristina CAPANNI; Claudio STEFANELLI; Benedetta TANTINI; Claudio M. CALDARERA The involvement of p44/42 mitogen-activated protein kinase (MAPK) in the induction of ornithine decarboxylase (ODC) was investigated by using PD98059, a specific MAPK-kinase (MEK1/2...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 338 (2): 465–470.
Published: 22 February 1999
..., was observed. Although the activity level then decreased quickly, activity higher than the control level was observed for 48 h. PD98059, an inhibitor of MAP kinase, suppressed the hyperoxia-induced neurite extensions, suggesting the involvement of MAP-kinase activity in the mechanism of differentiation induced...
