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Keywords: GLI1
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Biochem J (2006) 394 (1): 19–26.
Published: 27 January 2006
... through SMO (Smoothened) and represses the expression of HH target genes such as the transcription factor GLI1 ( gli oma 1 ) as well as PTCH1 . Up-regulation of these genes has been observed in several cancer forms, including basal cell carcinoma, digestive track tumours and small cell lung cancer...