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Keywords: BRCA1
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Biochem J (2021) 478 (18): 3467–3483.
Published: 30 September 2021
...Samuel R. Witus; Mikaela D. Stewart; Rachel E. Klevit Mutations in breast cancer type 1 susceptibility protein (BRCA1) and its heterodimeric binding partner BARD1 confer a high risk for the development of breast and ovarian cancers. The sole enzymatic function of the BRCA1/BARD1 complex...
Biochem J (2016) 473 (7): 949–960.
Published: 29 March 2016
...Anne Vincent; Elise Berthel; Estelle Dacheux; Clémence Magnard; Nicole L. Dalla Venezia The tumour suppressor BRCA1 (breast and ovarian cancer-susceptibility gene 1) is implicated in several nuclear processes including DNA repair, transcription regulation and chromatin remodelling. BRCA1 also has...
Includes: Supplementary data
Biochem J (2015) 466 (3): 613–624.
Published: 06 March 2015
...David C.A. Gaboriau; Pamela J.E. Rowling; Ciaran G. Morrison; Laura S. Itzhaki Mutations in breast cancer susceptibility gene BRCA1 (breast cancer early-onset 1) are associated with increased risk of developing breast and ovarian cancers. BRCA1 is a large protein of 1863 residues with two small...
Includes: Supplementary data