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Keywords: 3-hydroxy-3-methylglutaryl-CoA synthase-2
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Biochem J (2024) 481 (4): 295–312.
Published: 19 February 2024
...-Hydroxy-3-methylglutaryl-CoA synthase-2 (HMGCS2) mediates the rate-limiting step in this mitochondrial pathway. Publicly available databases show marked down-regulation of HMGCS2 in colonic tissues in Crohn's disease and ulcerative colitis. This led us to investigate the expression and function...
Includes: Supplementary data