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Keywords: α-difluoromethylornithine
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Biochem J (2011) 438 (2): 229–244.
Published: 12 August 2011
... is considered. α-difluoromethylornithine Leishmania malaria ornithine decarboxylase (ODC) polyamine S -adenosylmethionine decarboxylase (AdoMetDC) spermidine synthase Trypanosoma Both of the human aminopropyltransferases SpdS and SpmS exist as dimers of two identical subunits. Neither...
Includes: Multimedia, Supplementary data
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Biochem J (2000) 346 (1): 185–191.
Published: 08 February 2000
... decarboxylase, two key enzymes in polyamine biosynthesis. To identify mRNAs that respond to polyamine starvation, we treated Rat-2 cells with α-difluoromethylornithine, a specific inhibitor of polyamine biosynthesis. We isolated 41 partial cDNA clones, representing 37 differentially expressed mRNAs...
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Biochem J (1999) 338 (2): 317–323.
Published: 22 February 1999
...±0.04 µ M). Treatment of fibroblasts with either heparan sulphate lyase, p -nitrophenyl- O -β- d -xylopyranoside or chlorate reduced spermine uptake considerably, whereas chondroitin sulphate lyase had a limited effect. Inhibition of polyamine biosynthesis with α-difluoromethylornithine resulted...