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Articles

Root system growth and development responses to elevated CO 2 : underlying signalling mechanisms and role in improving plant CO 2 capture and soil C storage

In Collection
Plants and climate change: the role of plants in achieving net zero
Liên Bach, Alain Gojon
Journal: Biochemical Journal
Biochem J (2023) 480 (11): 753–771.
DOI: https://doi.org/10.1042/BCJ20220245
Published: 02 June 2023
View article titled, Root system growth and development responses to elevated CO 2 : underlying signalling mechanisms and role in improving plant CO 2 capture and soil C storage
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Articles

The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase

A. Jane Bardwell, Madhuri Paul, Kiku C. Yoneda, María D. Andrade-Ludeña, Oanh T. Nguyen, David A. Fruman, Lee Bardwell
Journal: Biochemical Journal
Biochem J (2023) 480 (10): 729–750.
DOI: https://doi.org/10.1042/BCJ20220493
Published: 26 May 2023
View article titled, The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase
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Articles

Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia

W. Bruce Sneddon, Peter A. Friedman, Tatyana Mamonova
Journal: Biochemical Journal
Biochem J (2023) 480 (9): 685–699.
DOI: https://doi.org/10.1042/BCJ20230020
Published: 17 May 2023
View article titled, Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia
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Articles

ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1

In Collection
Cell signaling in the 21st century
Kathryn Balmanno, Andrew M. Kidger, Dominic P. Byrne, Matthew J. Sale, Nejma Nassman, Patrick A. Eyers, Simon J. Cook
Journal: Biochemical Journal
Biochem J (2023) 480 (9): 587–605.
DOI: https://doi.org/10.1042/BCJ20220598
Published: 04 May 2023
View article titled, ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1
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Includes: Supplementary data
Articles

Overexpression of ARM repeat/U-box containing E3 ligase, PUB2 positively regulates growth and oxidative stress response in Arabidopsis

In Collection
Plants and climate change: the role of plants in achieving net zero
Lokesh K. Saini, Manisha Sharma, Barkha Ravi, Soma Ghosh, Sonam Pahuja, Nidhi Singh, Girdhar K. Pandey
Journal: Biochemical Journal
Biochem J (2023) 480 (9): 555–571.
DOI: https://doi.org/10.1042/BCJ20230026
Published: 28 April 2023
View article titled, Overexpression of ARM repeat/U-box containing E3 ligase, PUB2 positively regulates growth and oxidative stress response in Arabidopsis
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Articles

Principles of phosphoproteomics and applications in cancer research

In Collection
Cell signaling in the 21st century
Luke Higgins, Henry Gerdes, Pedro R. Cutillas
Journal: Biochemical Journal
Biochem J (2023) 480 (6): 403–420.
DOI: https://doi.org/10.1042/BCJ20220220
Published: 24 March 2023
View article titled, Principles of phosphoproteomics and applications in cancer research
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Articles

Site I Q in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions

Edwin T. Gibbs, II, Chad A. Lerner, Mark A. Watson, Hoi-Shan Wong, Akos A. Gerencser, Martin D. Brand
Journal: Biochemical Journal
Biochem J (2023) 480 (5): 363–384.
DOI: https://doi.org/10.1042/BCJ20220611
Published: 15 March 2023
View article titled, Site I Q in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions
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Articles

Macropinocytosis: mechanisms and regulation

Gilbert Salloum, Anne R. Bresnick, Jonathan M. Backer
Journal: Biochemical Journal
Biochem J (2023) 480 (5): 335–362.
DOI: https://doi.org/10.1042/BCJ20210584
Published: 15 March 2023
View article titled, Macropinocytosis: mechanisms and regulation
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Includes: Multimedia, Supplementary data
Articles

Protein kinase C showcases allosteric control: activation of LRRK1

Hannah Tovell, Alexandra C. Newton
Journal: Biochemical Journal
Biochem J (2023) 480 (3): 219–223.
DOI: https://doi.org/10.1042/BCJ20220507
Published: 10 February 2023
View article titled, Protein kinase C showcases allosteric control: activation of LRRK1
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Articles

BH3 mimetics and TKI combined therapy for Chronic Myeloid Leukemia

In Collection
Cell death and survival
Gabriela Brumatti, Deeksha Kaloni, Fabíola Attié Castro, Gustavo P. Amarante-Mendes
Journal: Biochemical Journal
Biochem J (2023) 480 (2): 161–176.
DOI: https://doi.org/10.1042/BCJ20210608
Published: 31 January 2023
View article titled, BH3 mimetics and TKI combined therapy for Chronic Myeloid Leukemia
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Articles

Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2

In Collection
Cell signaling in the 21st century
Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E. Eyers, Natarajan Kannan, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2023) 480 (2): 141–160.
DOI: https://doi.org/10.1042/BCJ20220474
Published: 23 January 2023
View article titled, Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2
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Includes: Multimedia, Supplementary data
Articles

Structural features of sensory two component systems: a synthetic biology perspective

Marcos Nieves, Alejandro Buschiazzo, Felipe Trajtenberg
Journal: Biochemical Journal
Biochem J (2023) 480 (2): 127–140.
DOI: https://doi.org/10.1042/BCJ20210798
Published: 23 January 2023
View article titled, Structural features of sensory two component systems: a synthetic biology perspective
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Articles

Characterizing crosstalk in epigenetic signaling to understand disease physiology

In Collection
Cell signaling in the 21st century
Joanna K. Lempiäinen, Benjamin A. Garcia
Journal: Biochemical Journal
Biochem J (2023) 480 (1): 57–85.
DOI: https://doi.org/10.1042/BCJ20220550
Published: 11 January 2023
View article titled, Characterizing crosstalk in epigenetic signaling to understand disease physiology
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Articles

Dynamic regulation of RAS and RAS signaling

In Collection
Cell signaling in the 21st century
Walter Kolch, Dénes Berta, Edina Rosta
Journal: Biochemical Journal
Biochem J (2023) 480 (1): 1–23.
DOI: https://doi.org/10.1042/BCJ20220234
Published: 06 January 2023
View article titled, Dynamic regulation of RAS and RAS signaling
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Articles

Activity of EGFR transmembrane region variants indicates specific transmembrane dimers are not required for EGFR activity

Foteini Bartzoka, Monica Gonzalez-Magaldi, Patrick O. Byrne, Nicole I. Callery, Kalina Hristova, Daniel J. Leahy
Journal: Biochemical Journal
Biochem J (2022) 479 (24): 2465–2475.
DOI: https://doi.org/10.1042/BCJ20220472
Published: 19 December 2022
View article titled, Activity of EGFR transmembrane region variants indicates specific transmembrane dimers are not required for EGFR activity
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Includes: Supplementary data
Articles

Regulation of B cell receptor signalling by Epstein–Barr virus nuclear antigens

Sarika Khasnis, Hildegonda Veenstra, Michael J. McClellan, Opeoluwa Ojeniyi, C. David Wood, Michelle J. West
Journal: Biochemical Journal
Biochem J (2022) 479 (23): 2395–2417.
DOI: https://doi.org/10.1042/BCJ20220417
Published: 07 December 2022
View article titled, Regulation of B cell receptor signalling by Epstein–Barr virus nuclear antigens
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Includes: Supplementary data
Articles

Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner

Enoli De Silva, Dana V. Devine, Eric Jan, Calvin D. Roskelley, Hugh Kim
Journal: Biochemical Journal
Biochem J (2022) 479 (22): 2351–2364.
DOI: https://doi.org/10.1042/BCJ20220177
Published: 23 November 2022
View article titled, Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner
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Includes: Supplementary data
Articles

AMP-activated protein kinase — a journey from 1 to 100 downstream targets

In Collection
Awards
D. Grahame Hardie
Journal: Biochemical Journal
Biochem J (2022) 479 (22): 2327–2343.
DOI: https://doi.org/10.1042/BCJ20220255
Published: 16 November 2022
View article titled, AMP-activated protein kinase — a journey from 1 to 100 downstream targets
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Articles

PI(4,5)P 2 : signaling the plasma membrane

Rachel C. Wills, Gerald R. V. Hammond
Journal: Biochemical Journal
Biochem J (2022) 479 (21): 2311–2325.
DOI: https://doi.org/10.1042/BCJ20220445
Published: 11 November 2022
View article titled, PI(4,5)P 2 : signaling the plasma membrane
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Articles

Methylglyoxal induces multiple serine phosphorylation in insulin receptor substrate 1 via the TAK1–p38–mTORC1 signaling axis in adipocytes

Su-Ping Ng, Wataru Nomura, Haruya Takahashi, Kazuo Inoue, Teruo Kawada, Tsuyoshi Goto, Yoshiharu Inoue
Journal: Biochemical Journal
Biochem J (2022) 479 (21): 2279–2296.
DOI: https://doi.org/10.1042/BCJ20220271
Published: 04 November 2022
View article titled, Methylglyoxal induces multiple serine phosphorylation in insulin receptor substrate 1 via the TAK1–p38–mTORC1 signaling axis in adipocytes
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Includes: Supplementary data
Articles

Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development

Qian Wei, Kjetil Taskén
Journal: Biochemical Journal
Biochem J (2022) 479 (20): 2219–2260.
DOI: https://doi.org/10.1042/BCJ20210233
Published: 28 October 2022
View article titled, Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development
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Articles

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte, Philip Cohen
Journal: Biochemical Journal
Biochem J (2022) 479 (20): 2195–2216.
DOI: https://doi.org/10.1042/BCJ20220401
Published: 21 October 2022
View article titled, Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC
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Includes: Supplementary data
Articles

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

Jill E. Hunter, Amy E. Campbell, Jacqueline A. Butterworth, Helene Sellier, Nicola L. Hannaway, Saimir Luli, Achilleas Floudas, Niall S. Kenneth, Adam J. Moore, Philip J. Brownridge, Huw D. Thomas, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S.R. Hasoon, Andrew M. Knight, Michelle D. Garrett, Ian Collins, Claire E. Eyers, Neil D. Perkins
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2087–2113.
DOI: https://doi.org/10.1042/BCJ20220089
Published: 14 October 2022
View article titled, Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance
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Includes: Supplementary data
Articles

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

Jill E. Hunter, Amy E. Campbell, Nicola L. Hannaway, Scott Kerridge, Saimir Luli, Jacqueline A. Butterworth, Helene Sellier, Reshmi Mukherjee, Nikita Dhillon, Praveen D. Sudhindar, Ruchi Shukla, Philip J. Brownridge, Hayden L. Bell, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S.R. Hasoon, Ian Collins, Michelle D. Garrett, Claire E. Eyers, Neil D. Perkins
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2063–2086.
DOI: https://doi.org/10.1042/BCJ20220102
Published: 14 October 2022
View article titled, Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway
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Includes: Supplementary data
Articles

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

Jill E. Hunter, Amy E. Campbell, Scott Kerridge, Callum Fraser, Nicola L. Hannaway, Saimir Luli, Iglika Ivanova, Philip J. Brownridge, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S. R. Hasoon, Claire E. Eyers, Neil D. Perkins
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2131–2151.
DOI: https://doi.org/10.1042/BCJ20220103
Published: 14 October 2022
View article titled, Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells
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Includes: Supplementary data
Articles

Mechanisms of TNF-independent RIPK3-mediated cell death

Bart Tummers, Douglas R. Green
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2049–2062.
DOI: https://doi.org/10.1042/BCJ20210724
Published: 14 October 2022
View article titled, Mechanisms of TNF-independent RIPK3-mediated cell death
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Articles

PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the COR B GTPase domain

Asad U. Malik, Athanasios Karapetsas, Raja S. Nirujogi, Deep Chatterjee, Toan K. Phung, Melanie Wightman, Robert Gourlay, Nick Morrice, Sebastian Mathea, Stefan Knapp, Dario R. Alessi
Journal: Biochemical Journal
Biochem J (2022) 479 (18): 1941–1965.
DOI: https://doi.org/10.1042/BCJ20220308
Published: 23 September 2022
View article titled, PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the COR B GTPase domain
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Articles

Combinatorial approaches for mitigating resistance to KRAS-targeted therapies

Hannah R. Warren, Sarah J. Ross, Paul D. Smith, Judy M. Coulson, Ian A. Prior
Journal: Biochemical Journal
Biochem J (2022) 479 (18): 1985–1997.
DOI: https://doi.org/10.1042/BCJ20220440
Published: 23 September 2022
View article titled, Combinatorial approaches for mitigating resistance to KRAS-targeted therapies
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Includes: Supplementary data
Articles

TOR complex 2 is a master regulator of plasma membrane homeostasis

In Collection
Awards
Jeremy Thorner
Journal: Biochemical Journal
Biochem J (2022) 479 (18): 1917–1940.
DOI: https://doi.org/10.1042/BCJ20220388
Published: 23 September 2022
View article titled, TOR complex 2 is a master regulator of plasma membrane homeostasis
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Includes: Supplementary data
Articles

Divergent kinase WNG1 is regulated by phosphorylation of an atypical activation sub-domain

Pravin S. Dewangan, Tsebaot G. Beraki, E. Ariana Paiz, Delia Appiah Mensah, Zhe Chen, Michael L. Reese
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1877–1889.
DOI: https://doi.org/10.1042/BCJ20220076
Published: 16 September 2022
View article titled, Divergent kinase WNG1 is regulated by phosphorylation of an atypical activation sub-domain
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Includes: Supplementary data
Articles

TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells

Melissa Rodrigues, Tsvetana Petrova, Brendan Tibbs, J. Simon C. Arthur, Philip Cohen
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1891–1907.
DOI: https://doi.org/10.1042/BCJ20220314
Published: 16 September 2022
View article titled, TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells
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Includes: Supplementary data
Articles

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding

Alexia F. Kalogeropulou, Elena Purlyte, Francesca Tonelli, Sven M. Lange, Melanie Wightman, Alan R. Prescott, Shalini Padmanabhan, Esther Sammler, Dario R. Alessi
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1759–1783.
DOI: https://doi.org/10.1042/BCJ20220161
Published: 06 September 2022
View article titled, Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
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Includes: Supplementary data
Articles

Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth

Ksenija Korac, Devaraja Rajasekaran, Tyler Sniegowski, Bradley K. Schniers, Andrew F. Ibrahim, Yangzom D. Bhutia
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1807–1824.
DOI: https://doi.org/10.1042/BCJ20210851
Published: 06 September 2022
View article titled, Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth
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Includes: Supplementary data
Articles

Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells

Gavuthami Murugesan, Alan R. Prescott, Rachel Toth, David G. Campbell, Claire M. Wells, Carol MacKintosh
Journal: Biochemical Journal
Biochem J (2022) 479 (16): 1709–1725.
DOI: https://doi.org/10.1042/BCJ20220184
Published: 31 August 2022
View article titled, Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells
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Includes: Supplementary data
Articles

Cell death in skin function, inflammation, and disease

In Collection
Cell death and survival
Holly Anderton, Suhaib Alqudah
Journal: Biochemical Journal
Biochem J (2022) 479 (15): 1621–1651.
DOI: https://doi.org/10.1042/BCJ20210606
Published: 05 August 2022
View article titled, Cell death in skin function, inflammation, and disease
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Articles

PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responses

Jacqueline J.T. Marshall, Joshua J. Cull, Hajed O. Alharbi, May Zaw Thin, Susanna T.E. Cooper, Christopher Barrington, Hannah Vanyai, Thomas Snoeks, Bernard Siow, Alejandro Suáarez-Bonnet, Eleanor Herbert, Daniel J. Stuckey, Angus J.M. Cameron, Fabrice Prin, Andrew C. Cook, Simon L. Priestnall, Sonia Chotani, Owen J. L. Rackham, Daniel N. Meijles, Tim Mohun, Angela Clerk, Peter J. Parker
Journal: Biochemical Journal
Biochem J (2022) 479 (13): 1467–1486.
DOI: https://doi.org/10.1042/BCJ20220281
Published: 12 July 2022
View article titled, PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responses
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Includes: Multimedia, Supplementary data
Articles

Deciphering signal transduction networks in the liver by mechanistic mathematical modelling

Lorenza A. D’Alessandro, Ursula Klingmüller, Marcel Schilling
Journal: Biochemical Journal
Biochem J (2022) 479 (12): 1361–1374.
DOI: https://doi.org/10.1042/BCJ20210548
Published: 24 June 2022
View article titled, Deciphering signal transduction networks in the liver by mechanistic mathematical modelling
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Articles

Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators

Manuel Johanns, Cyril Corbet, Roxane Jacobs, Melissa Drappier, Guido T. Bommer, Gaëtan Herinckx, Didier Vertommen, Nicolas Tajeddine, David Young, Joris Messens, Olivier Feron, Gregory R. Steinberg, Louis Hue, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2022) 479 (12): 1317–1336.
DOI: https://doi.org/10.1042/BCJ20220170
Published: 22 June 2022
View article titled, Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators
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Includes: Supplementary data
Articles

Anti-tumor and anti-metastatic activity of the FGF2 118–126 fragment dependent on the loop structure

Hossein Allahmoradi, S. Mohsen Asghari, Atieh Ahmadi, Elham Assareh, Mahboobeh Nazari
Journal: Biochemical Journal
Biochem J (2022) 479 (12): 1285–1302.
DOI: https://doi.org/10.1042/BCJ20210830
Published: 21 June 2022
View article titled, Anti-tumor and anti-metastatic activity of the FGF2 118–126 fragment dependent on the loop structure
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Includes: Supplementary data
Articles

Towards ‘end-to-end’ analysis and understanding of biological timecourse data

In Collection
Towards systems biochemistry
Siddhartha G. Jena, Alexander G. Goglia, Barbara E. Engelhardt
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1257–1263.
DOI: https://doi.org/10.1042/BCJ20220053
Published: 17 June 2022
View article titled, Towards ‘end-to-end’ analysis and understanding of biological timecourse data
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Articles

Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate

Xiaowen Duan, Dougall M. Norris, Sean J. Humphrey, Pengyi Yang, Kristen C. Cooke, Will P. Bultitude, Benjamin L. Parker, Olivia J. Conway, James G. Burchfield, James R. Krycer, Frances M. Brodsky, David E. James, Daniel J. Fazakerley
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1237–1256.
DOI: https://doi.org/10.1042/BCJ20220153
Published: 13 June 2022
View article titled, Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate
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Includes: Supplementary data
Articles

NUCKS1 is a highly modified, chromatin-associated protein involved in a diverse set of biological and pathophysiological processes

Anne Carine Østvold, Kirsten Grundt, Claudia Wiese
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1205–1220.
DOI: https://doi.org/10.1042/BCJ20220075
Published: 13 June 2022
View article titled, NUCKS1 is a highly modified, chromatin-associated protein involved in a diverse set of biological and pathophysiological processes
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Articles

NAD-catabolizing ectoenzymes of Schistosoma mansoni

Catherine S. Nation, Akram A. Da'Dara, Patrick J. Skelly
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1165–1180.
DOI: https://doi.org/10.1042/BCJ20210784
Published: 08 June 2022
View article titled, NAD-catabolizing ectoenzymes of Schistosoma mansoni
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Articles

Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway

In Collection
Cell death and survival
Neil D. Perkins
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1121–1126.
DOI: https://doi.org/10.1042/BCJ20220023
Published: 01 June 2022
View article titled, Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway
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Articles

Deubiquitinases in cell death and inflammation

In Collection
Cell death and survival
Kim Newton, Alexander D. Gitlin
Journal: Biochemical Journal
Biochem J (2022) 479 (10): 1103–1119.
DOI: https://doi.org/10.1042/BCJ20210735
Published: 24 May 2022
View article titled, Deubiquitinases in cell death and inflammation
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Articles

No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death

In Collection
Cell death and survival
Ashley Weir, James E. Vince
Journal: Biochemical Journal
Biochem J (2022) 479 (10): 1083–1102.
DOI: https://doi.org/10.1042/BCJ20210711
Published: 24 May 2022
View article titled, No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death
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Articles

The role of eIF2 phosphorylation in cell and organismal physiology: new roles for well-known actors

Xuemin Wang, Christopher G. Proud
Journal: Biochemical Journal
Biochem J (2022) 479 (10): 1059–1082.
DOI: https://doi.org/10.1042/BCJ20220068
Published: 23 May 2022
View article titled, The role of eIF2 phosphorylation in cell and organismal physiology: new roles for well-known actors
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Articles

Alveolar cells in the mammary gland: lineage commitment and cell death

In Collection
Cell death and survival
Christine J. Watson
Journal: Biochemical Journal
Biochem J (2022) 479 (9): 995–1006.
DOI: https://doi.org/10.1042/BCJ20210734
Published: 12 May 2022
View article titled, Alveolar cells in the mammary gland: lineage commitment and cell death
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Articles

RIP1 post-translational modifications

In Collection
Cell death and survival
Eugene Varfolomeev, Domagoj Vucic
Journal: Biochemical Journal
Biochem J (2022) 479 (9): 929–951.
DOI: https://doi.org/10.1042/BCJ20210725
Published: 06 May 2022
View article titled, RIP1 post-translational modifications
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Articles

Quantitative live-cell imaging of GPCR downstream signaling dynamics

In Collection
Towards systems biochemistry
Ryosuke Tany, Yuhei Goto, Yohei Kondo, Kazuhiro Aoki
Journal: Biochemical Journal
Biochem J (2022) 479 (8): 883–900.
DOI: https://doi.org/10.1042/BCJ20220021
Published: 21 April 2022
View article titled, Quantitative live-cell imaging of GPCR downstream signaling dynamics
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Includes: Supplementary data