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BH3 mimetics and TKI combined therapy for Chronic Myeloid Leukemia

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Cell death and survival

Gabriela Brumatti, Deeksha Kaloni, Fabíola Attié Castro, Gustavo P. Amarante-Mendes

Biochem J (2023) 480 (2): 161–176.

DOI: https://doi.org/10.1042/BCJ20210608

Published: 31 January 2023

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Articles

Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner

Enoli De Silva, Dana V. Devine, Eric Jan, Calvin D. Roskelley, Hugh Kim

Biochem J (2022) 479 (22): 2351–2364.

DOI: https://doi.org/10.1042/BCJ20220177

Published: 23 November 2022

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AMP-activated protein kinase — a journey from 1 to 100 downstream targets

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Awards

D. Grahame Hardie

Biochem J (2022) 479 (22): 2327–2343.

DOI: https://doi.org/10.1042/BCJ20220255

Published: 16 November 2022

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Mechanisms of TNF-independent RIPK3-mediated cell death

Bart Tummers, Douglas R. Green

Biochem J (2022) 479 (19): 2049–2062.

DOI: https://doi.org/10.1042/BCJ20210724

Published: 14 October 2022

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Articles

PON2 mediates mitochondrial dysfunction in tracheal epithelial cells in response to a quorum sensing molecule N-(-3-oxododecanoyl)-l-homoserine lactone

Aaron G. Whitt, Shuhan Meng, Jiu-Zhen Jin, Lindsey R. Conroy, Lindsey A. McNally, Joseph A. Burlison, Bradford G. Hill, Brian F. Clem, Carl White, Chi Li

Biochem J (2022) 479 (19): 2013–2034.

DOI: https://doi.org/10.1042/BCJ20220100

Published: 07 October 2022

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Includes: Supplementary data

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Cell death in skin function, inflammation, and disease

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Cell death and survival

Holly Anderton, Suhaib Alqudah

Biochem J (2022) 479 (15): 1621–1651.

DOI: https://doi.org/10.1042/BCJ20210606

Published: 05 August 2022

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Articles

The cross-talk of autophagy and apoptosis in breast carcinoma: implications for novel therapies?

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Cell death and survival

Kamil Seyrek, Fabian Wohlfromm, Johannes Espe, Inna N. Lavrik

Biochem J (2022) 479 (14): 1581–1608.

DOI: https://doi.org/10.1042/BCJ20210676

Published: 29 July 2022

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Articles

Distinct interactors define the p63 transcriptional signature in epithelial development or cancer

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Cell death and survival

Rosalba Pecorari, Francesca Bernassola, Gerry Melino, Eleonora Candi

Biochem J (2022) 479 (12): 1375–1392.

DOI: https://doi.org/10.1042/BCJ20210737

Published: 24 June 2022

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Articles

Anti-tumor and anti-metastatic activity of the FGF2 118–126 fragment dependent on the loop structure

Hossein Allahmoradi, S. Mohsen Asghari, Atieh Ahmadi, Elham Assareh, Mahboobeh Nazari

Biochem J (2022) 479 (12): 1285–1302.

DOI: https://doi.org/10.1042/BCJ20210830

Published: 21 June 2022

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Includes: Supplementary data

Articles

Characterization of uridine-cytidine kinase like-1 nucleoside kinase activity and its role in tumor growth

Emily C. Matchett, Elise C. Ambrose, Jacki Kornbluth

Biochem J (2022) 479 (11): 1149–1164.

DOI: https://doi.org/10.1042/BCJ20210770

Published: 08 June 2022

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Articles

Deubiquitinases in cell death and inflammation

Kim Newton, Alexander D. Gitlin

Biochem J (2022) 479 (10): 1103–1119.

DOI: https://doi.org/10.1042/BCJ20210735

Published: 24 May 2022

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Articles

No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death

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Cell death and survival

Ashley Weir, James E. Vince

Biochem J (2022) 479 (10): 1083–1102.

DOI: https://doi.org/10.1042/BCJ20210711

Published: 24 May 2022

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Articles

Alveolar cells in the mammary gland: lineage commitment and cell death

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Cell death and survival

Christine J. Watson

Biochem J (2022) 479 (9): 995–1006.

DOI: https://doi.org/10.1042/BCJ20210734

Published: 12 May 2022

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Articles

RIP1 post-translational modifications

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Cell death and survival

Eugene Varfolomeev, Domagoj Vucic

Biochem J (2022) 479 (9): 929–951.

DOI: https://doi.org/10.1042/BCJ20210725

Published: 06 May 2022

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Articles

Ferroptosis in plants: regulation of lipid peroxidation and redox status

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Cell death and survival

Ayelén Mariana Distéfano, Gabriel Alejandro López, Victoria Bauer, Eduardo Zabaleta, Gabriela Carolina Pagnussat

Biochem J (2022) 479 (7): 857–866.

DOI: https://doi.org/10.1042/BCJ20210682

Published: 19 April 2022

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Articles

Activation and manipulation of inflammasomes and pyroptosis during bacterial infections

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Cell death and survival

Elliott M. Bernard, Petr Broz

Biochem J (2022) 479 (7): 867–882.

DOI: https://doi.org/10.1042/BCJ20220051

Published: 19 April 2022

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Articles

Regulation of the release of damage-associated molecular patterns from necroptotic cells

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Cell death and survival

Hiroyasu Nakano, Shin Murai, Kenta Moriwaki

Biochem J (2022) 479 (5): 677–685.

DOI: https://doi.org/10.1042/BCJ20210604

Published: 16 March 2022

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Includes: Supplementary data

Articles

Programmed cell death: the pathways to severe COVID-19?

Stefanie M. Bader, James P. Cooney, Marc Pellegrini, Marcel Doerflinger

Biochem J (2022) 479 (5): 609–628.

DOI: https://doi.org/10.1042/BCJ20210602

Published: 04 March 2022

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Articles

The concept of intrinsic versus extrinsic apoptosis

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Cell death and survival

Laura Lossi

Biochem J (2022) 479 (3): 357–384.

DOI: https://doi.org/10.1042/BCJ20210854

Published: 11 February 2022

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Articles

TAT–RHIM: a more complex issue than expected

Benedikt Kolbrink, Theresa Riebeling, Nikolas K. Teiwes, Claudia Steinem, Hubert Kalbacher, Ulrich Kunzendorf, Stefan Krautwald

Biochem J (2022) 479 (3): 259–272.

DOI: https://doi.org/10.1042/BCJ20210677

Published: 04 February 2022

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Articles

IKKα plays a major role in canonical NF-κB signalling in colorectal cells

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Cell death and survival

Jack A. Prescott, Kathryn Balmanno, Jennifer P. Mitchell, Hanneke Okkenhaug, Simon J. Cook

Biochem J (2022) 479 (3): 305–325.

DOI: https://doi.org/10.1042/BCJ20210783

Published: 04 February 2022

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Includes: Supplementary data

Articles

The complex interplay between autophagy and cell death pathways

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Cell death and survival

Christina Ploumi, Margarita-Elena Papandreou, Nektarios Tavernarakis

Biochem J (2022) 479 (1): 75–90.

DOI: https://doi.org/10.1042/BCJ20210450

Published: 14 January 2022

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Articles

The unfolding role of ceramide in coordinating retinoid-based cancer therapy

Botheina Ghandour, Ghassan Dbaibo, Nadine Darwiche

Biochem J (2021) 478 (19): 3621–3642.

DOI: https://doi.org/10.1042/BCJ20210368

Published: 14 October 2021

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Articles

Kinases leave their mark on caspase substrates

Amy M. Weeks

Biochem J (2021) 478 (17): 3179–3184.

DOI: https://doi.org/10.1042/BCJ20210399

Published: 07 September 2021

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Articles

Inhibitory feedback control of NF-κB signalling in health and disease

Jack A. Prescott, Jennifer P. Mitchell, Simon J. Cook

Biochem J (2021) 478 (13): 2619–2664.

DOI: https://doi.org/10.1042/BCJ20210139

Published: 16 July 2021

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Articles

Elongation factor eEF2 kinase and autophagy jointly promote survival of cancer cells

Roman V. Lenchine, Sushma R. Rao, Xuemin Wang, Danielle Meiwen Fang, Christopher G. Proud

Biochem J (2021) 478 (8): 1547–1569.

DOI: https://doi.org/10.1042/BCJ20210126

Published: 21 April 2021

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Includes: Supplementary data

Articles

Lupeol-induced nitric oxide elicits apoptosis-like death within Escherichia coli in a DNA fragmentation-independent manner

Heesu Kim, Dong Gun Lee

Biochem J (2021) 478 (4): 855–869.

DOI: https://doi.org/10.1042/BCJ20200925

Published: 24 February 2021

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Articles

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity

Matthias Fellner, Rinky Parakra, Kirstin O. McDonald, Itamar Kass, Guy N.L. Jameson, Sigurd M. Wilbanks, Elizabeth C. Ledgerwood

Biochem J (2021) 478 (3): 669–684.

DOI: https://doi.org/10.1042/BCJ20200793

Published: 12 February 2021

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Includes: Supplementary data

Articles

Hyperthermia induced disruption of mechanical balance leads to G1 arrest and senescence in cells

Nikita Mundhara, Abhijit Majumder, Dulal Panda

Biochem J (2021) 478 (1): 179–196.

DOI: https://doi.org/10.1042/BCJ20200705

Published: 13 January 2021

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Includes: Supplementary data

Articles

Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis

Chathura D. Suraweera, Mark G. Hinds, Marc Kvansakul

Biochem J (2020) 477 (23): 4527–4541.

DOI: https://doi.org/10.1042/BCJ20200776

Published: 03 December 2020

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Includes: Supplementary data

Articles

Chemically based transmissible ER stress protocols are unsuitable to study cell-to-cell UPR transmission

Yohan Bignon, Virginie Poindessous, Luca Rampoldi, Violette Haldys, Nicolas Pallet

Biochem J (2020) 477 (20): 4037–4051.

DOI: https://doi.org/10.1042/BCJ20200699

Published: 29 October 2020

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Includes: Supplementary data

Articles

Heat shock protein 90 inhibitors suppress pyroptosis in THP-1 cells

Zhou Zhou, Xiuzhen Li, Yisong Qian, Cynthia Liu, Xiaotian Huang, Mingui Fu

Biochem J (2020) 477 (20): 3923–3934.

DOI: https://doi.org/10.1042/BCJ20200351

Published: 23 October 2020

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Articles

The structural basis of Bcl-2 mediated cell death regulation in hydra

Suresh Banjara, Jaison D Sa, Mark G. Hinds, Marc Kvansakul

Biochem J (2020) 477 (17): 3287–3297.

DOI: https://doi.org/10.1042/BCJ20200556

Published: 10 September 2020

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Articles

ALG2 Influences T cell apoptosis by regulating FASLG intracellular transportation

Wangsheng Ji, Yang Xin, Lianfei Zhang, Xinqi Liu

Biochem J (2020) 477 (16): 3105–3121.

DOI: https://doi.org/10.1042/BCJ20200028

Published: 28 August 2020

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Articles

Cr(VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes

Yujing Zhang, Huanfeng Bian, Yu Ma, Yuanyuan Xiao, Fang Xiao

Biochem J (2020) 477 (14): 2607–2619.

DOI: https://doi.org/10.1042/BCJ20200262

Published: 24 July 2020

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Articles

Synthesis and high antiproliferative activity of dehydroabietylamine pyridine derivatives in vitro and in vivo

Fengyi Zhao, Wen Lu, Yuanyuan Xu, Li Xu, Jingjing Zhang, Xu Sun, Shilong Yang, Mengyi Zhou, Fan Su, Feng Lin, Fuliang Cao

Biochem J (2020) 477 (12): 2383–2399.

DOI: https://doi.org/10.1042/BCJ20200337

Published: 26 June 2020

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Includes: Supplementary data

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A nonpeptidyl molecule modulates apoptosis-like cell death by inhibiting P. falciparum metacaspase-2

Vandana, Sudha Shankar, Kona Madhavinadha Prasad, Mohammad Kashif, Inderjeet Kalia, Rajkishor Rai, Agam P. Singh, Kailash C. Pandey

Biochem J (2020) 477 (7): 1323–1344.

DOI: https://doi.org/10.1042/BCJ20200050

Published: 17 April 2020

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Interaction of α-synuclein and Parkin in iron toxicity on SH-SY5Y cells: implications in the pathogenesis of Parkinson's disease

Upasana Ganguly, Anindita Banerjee, Sankha Shubhra Chakrabarti, Upinder Kaur, Oishimaya Sen, Roberto Cappai, Sasanka Chakrabarti

Biochem J (2020) 477 (6): 1109–1122.

DOI: https://doi.org/10.1042/BCJ20190676

Published: 23 March 2020

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Articles

A lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells

Logan Slade, Dipsikha Biswas, Francis Ihionu, Yassine El Hiani, Petra C. Kienesberger, Thomas Pulinilkunnil

Biochem J (2020) 477 (1): 137–160.

DOI: https://doi.org/10.1042/BCJ20190596

Published: 10 January 2020

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Includes: Supplementary data

Articles

Astroglial contribution to tau-dependent neurodegeneration

Marta Sidoryk-Węgrzynowicz, Lidia Strużyńska

Biochem J (2019) 476 (22): 3493–3504.

DOI: https://doi.org/10.1042/BCJ20190506

Published: 27 November 2019

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Articles

Sab concentrations indicate chemotherapeutic susceptibility in ovarian cancer cell lines

Iru Paudel, Sean M. Hernandez, Gilda M. Portalatin, Tara P. Chambers, Jeremy W. Chambers

Biochem J (2018) 475 (21): 3471–3492.

DOI: https://doi.org/10.1042/BCJ20180603

Published: 15 November 2018

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Includes: Supplementary data

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The cloak, dagger, and shield: proteases in plant–pathogen interactions

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Editors' pick of review article highlights published in the Biochemical Journal in 2018 & 2019

Shuguo Hou, Pierce Jamieson, Ping He

Biochem J (2018) 475 (15): 2491–2509.

DOI: https://doi.org/10.1042/BCJ20170781

Published: 16 August 2018

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Articles

CGA-N12, a peptide derived from chromogranin A, promotes apoptosis of Candida tropicalis by attenuating mitochondrial functions

Ruifang Li, Ruiling Zhang, Yanhui Yang, Xueqin Wang, Yanjie Yi, Pei Fan, Zhengwei Liu, Chen Chen, Junpeng Chang

Biochem J (2018) 475 (7): 1385–1396.

DOI: https://doi.org/10.1042/BCJ20170894

Published: 16 April 2018

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Articles

Mitochondrial DNA as an inflammatory mediator in cardiovascular diseases

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Editors' pick of review article highlights published in the Biochemical Journal in 2018 & 2019

Hiroyuki Nakayama, Kinya Otsu

Biochem J (2018) 475 (5): 839–852.

DOI: https://doi.org/10.1042/BCJ20170714

Published: 06 March 2018

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GPR4 knockout improves renal ischemia–reperfusion injury and inhibits apoptosis via suppressing the expression of CHOP

Biao Dong, Xiaolu Zhang, Yafeng Fan, Songqiang Cao, Xuepei Zhang

Biochem J (2017) 474 (24): 4065–4074.

DOI: https://doi.org/10.1042/BCJ20170676

Published: 01 December 2017

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Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates β-cell apoptosis via generation of oxidative stress

Richa Dubey, Pooja Minj, Nikita Malik, Devika M. Sardesai, Shruti H. Kulkarni, Jhankar D. Acharya, Neel Sarovar Bhavesh, Shilpy Sharma, Ashutosh Kumar

Biochem J (2017) 474 (23): 3915–3934.

DOI: https://doi.org/10.1042/BCJ20170323

Published: 16 November 2017

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Therapeutics targeting Bcl-2 in hematological malignancies

Astrid Ruefli-Brasse, John C. Reed

Biochem J (2017) 474 (21): 3643–3657.

DOI: https://doi.org/10.1042/BCJ20170080

Published: 23 October 2017

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Glycerol-3-phosphate acyltransferase 2 is essential for normal spermatogenesis

Maria B. Garcia-Fabiani, Mauro A. Montanaro, Pablo Stringa, Ezequiel Lacunza, Elizabeth R. Cattaneo, Marianela Santana, Magali Pellon-Maison, Maria R. Gonzalez-Baro

Biochem J (2017) 474 (18): 3093–3107.

DOI: https://doi.org/10.1042/BCJ20161018

Published: 31 August 2017

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The antifungal activity of the peptide, periplanetasin-2, derived from American cockroach Periplaneta americana

JiEun Yun, Jae-Sam Hwang, Dong Gun Lee

Biochem J (2017) 474 (17): 3027–3043.

DOI: https://doi.org/10.1042/BCJ20170461

Published: 22 August 2017

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Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway

Chunyang Du, Tao Zhang, Xia Xiao, Yonghong Shi, Huijun Duan, Yunzhuo Ren

Biochem J (2017) 474 (16): 2733–2747.

DOI: https://doi.org/10.1042/BCJ20170272

Published: 02 August 2017

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