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Self-assembly of Shell Protein and Native Enzyme in a Crowded Environment Leads to Catalytically Active Phase Condensates

Gaurav Kumar, SHARMISTHA SINHA

Biochem J (2023) BCJ20220551.

DOI: https://doi.org/10.1042/BCJ20220551

Published: 23 January 2023

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Dynamic regulation of RAS and RAS signaling

Walter Kolch, Dénes Berta, Edina Rosta

Biochem J (2023) 480 (1): 1–23.

DOI: https://doi.org/10.1042/BCJ20220234

Published: 06 January 2023

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Activity of EGFR transmembrane region variants indicates specific transmembrane dimers are not required for EGFR activity

Foteini Bartzoka, Monica Gonzalez-Magaldi, Patrick O. Byrne, Nicole I. Callery, Kalina Hristova, Daniel J. Leahy

Biochem J (2022) 479 (24): 2465–2475.

DOI: https://doi.org/10.1042/BCJ20220472

Published: 19 December 2022

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Therapeutic potential of metal ions for COVID-19: insights from the papain-like protease of SARS-CoV-2

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Coronavirus

Cameron Lee Shetler, Juliana C. Ferreira, Thyago H. S. Cardoso, Edson M.A. Silva, Nitin K. Saksena, Wael M. Rabeh

Biochem J (2022) 479 (20): 2175–2193.

DOI: https://doi.org/10.1042/BCJ20220380

Published: 21 October 2022

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The hydrophobic residue Leu73 is crucial for the high stability and low aggregation properties of murine transthyretin

Mei Nakagawa, Takayuki Obita, Mineyuki Mizuguchi

Biochem J (2022) 479 (18): 1999–2011.

DOI: https://doi.org/10.1042/BCJ20220203

Published: 30 September 2022

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Divergent kinase WNG1 is regulated by phosphorylation of an atypical activation sub-domain

Pravin S. Dewangan, Tsebaot G. Beraki, E. Ariana Paiz, Delia Appiah Mensah, Zhe Chen, Michael L. Reese

Biochem J (2022) 479 (17): 1877–1889.

DOI: https://doi.org/10.1042/BCJ20220076

Published: 16 September 2022

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Cryo-EM structure of human MG53 homodimer

Yange Niu, Gengjia Chen, Fengxiang Lv, Rui-Ping Xiao, Xinli Hu, Lei Chen

Biochem J (2022) 479 (17): 1909–1916.

DOI: https://doi.org/10.1042/BCJ20220385

Published: 16 September 2022

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How do cells stiffen?

Peter A. Galie, Penelope C. Georges, Paul A. Janmey

Biochem J (2022) 479 (17): 1825–1842.

DOI: https://doi.org/10.1042/BCJ20210806

Published: 12 September 2022

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Thermodynamic analysis of Zα domain-nucleic acid interactions

Bharath Srinivasan, Krzysztof Kuś, Alekos Athanasiadis

Biochem J (2022) 479 (16): 1727–1741.

DOI: https://doi.org/10.1042/BCJ20220200

Published: 31 August 2022

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Vitamin K3 inhibits FtsZ assembly, disrupts the Z-ring in Streptococcus pneumoniae and displays anti-pneumococcal activity

Athira Pushpakaran, Rachana Rao Battaje, Dulal Panda

Biochem J (2022) 479 (14): 1543–1558.

DOI: https://doi.org/10.1042/BCJ20220077

Published: 21 July 2022

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Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system

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Towards systems biochemistry

Atsushi Mukaiyama, Yoshihiko Furuike, Eiki Yamashita, Shuji Akiyama

Biochem J (2022) 479 (14): 1505–1515.

DOI: https://doi.org/10.1042/BCJ20210544

Published: 19 July 2022

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Binding partners regulate unfolding of myosin VI to activate the molecular motor

Ália dos Santos, Natalia Fili, Yukti Hari-Gupta, Rosemarie E. Gough, Lin Wang, Marisa Martin-Fernandez, Jesse Aaron, Eric Wait, Teng-Leong Chew, Christopher P. Toseland

Biochem J (2022) 479 (13): 1409–1428.

DOI: https://doi.org/10.1042/BCJ20220025

Published: 04 July 2022

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A structural approach to understanding enzymatic regulation of chemical reaction networks

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Towards systems biochemistry

Atsushi Mochizuki

Biochem J (2022) 479 (11): 1265–1283.

DOI: https://doi.org/10.1042/BCJ20210545

Published: 17 June 2022

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Integration of machine learning with computational structural biology of plants

Jiming Chen, Diwakar Shukla

Biochem J (2022) 479 (8): 921–928.

DOI: https://doi.org/10.1042/BCJ20200942

Published: 29 April 2022

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Allosteric pluripotency: challenges and opportunities

Madoka Akimoto, Karla Martinez Pomier, Bryan VanSchouwen, Jung Ah Byun, Mariia Khamina, Giuseppe Melacini

Biochem J (2022) 479 (7): 825–838.

DOI: https://doi.org/10.1042/BCJ20210528

Published: 11 April 2022

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α-Helix stabilization by co-operative side chain charge-reinforced interactions to phosphoserine in a basic kinase-substrate motif

Matthew Batchelor, Robert S. Dawber, Andrew J. Wilson, Richard Bayliss

Biochem J (2022) 479 (5): 687–700.

DOI: https://doi.org/10.1042/BCJ20210812

Published: 16 March 2022

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Quantifying the long-term interplay between photoprotection and repair mechanisms sustaining photosystem II activity

Francesco Saccon, Sam Wilson, Felix S. Morey-Burrows, Alexander V. Ruban

Biochem J (2022) 479 (5): 701–717.

DOI: https://doi.org/10.1042/BCJ20220031

Published: 16 March 2022

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Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase

Zhuoyao Chen, Jinwei Zhang, Adrián R. Murillo-de-Ozores, María Castañeda-Bueno, Francesca D'Amico, Raphael Heilig, Charlotte E. Manning, Fiona J. Sorrell, Vincenzo D'Angiolella, Roman Fischer, Monique P. C. Mulder, Gerardo Gamba, Dario R. Alessi, Alex N. Bullock

Biochem J (2022) 479 (5): 661–675.

DOI: https://doi.org/10.1042/BCJ20220019

Published: 04 March 2022

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N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum

Samuel Pazicky, Arne Alder, Haydyn Mertens, Dmitri Svergun, Tim Gilberger, Christian Löw

Biochem J (2022) 479 (3): 337–356.

DOI: https://doi.org/10.1042/BCJ20210829

Published: 04 February 2022

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Reconstitution of the DTX3L–PARP9 complex reveals determinants for high-affinity heterodimerization and multimeric assembly

Yashwanth Ashok, Carlos Vela-Rodríguez, Chunsong Yang, Heli I. Alanen, Fan Liu, Bryce M. Paschal, Lari Lehtiö

Biochem J (2022) 479 (3): 289–304.

DOI: https://doi.org/10.1042/BCJ20210722

Published: 04 February 2022

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Live imaging approach of dynamic multicellular responses in ERK signaling during vertebrate tissue development

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Towards systems biochemistry

Tsuyoshi Hirashima

Biochem J (2022) 479 (2): 129–143.

DOI: https://doi.org/10.1042/BCJ20210557

Published: 20 January 2022

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Articles

Electron transfer via cytochrome b 6 f complex displays sensitivity to antimycin A upon STT7 kinase activation

Felix Buchert, Martin Scholz, Michael Hippler

Biochem J (2022) 479 (1): 111–127.

DOI: https://doi.org/10.1042/BCJ20210802

Published: 14 January 2022

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Making protons tag along with electrons

Matthew J. Guberman-Pfeffer, Nikhil S. Malvankar

Biochem J (2021) 478 (23): 4093–4097.

DOI: https://doi.org/10.1042/BCJ20210592

Published: 06 December 2021

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Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 Å: the structural basis for dimerisation

Pu Qian, Tristan I. Croll, Andrew Hitchcock, Philip J. Jackson, Jack H. Salisbury, Pablo Castro-Hartmann, Kasim Sader, David J.K. Swainsbury, C. Neil Hunter

Biochem J (2021) 478 (21): 3923–3937.

DOI: https://doi.org/10.1042/BCJ20210696

Published: 09 November 2021

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Thermostability-based binding assays reveal complex interplay of cation, substrate and lipid binding in the bacterial DASS transporter, VcINDY

Connor D. D. Sampson, Cristina Fàbregas Bellavista, Matthew J. Stewart, Christopher Mulligan

Biochem J (2021) 478 (21): 3847–3867.

DOI: https://doi.org/10.1042/BCJ20210061

Published: 09 November 2021

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Quantitative characterization of tetraspanin 8 homointeractions in the plasma membrane

Daniel Wirth, Ece Özdemir, Christopher King, Lena Ahlswede, Dirk Schneider, Kalina Hristova

Biochem J (2021) 478 (19): 3643–3654.

DOI: https://doi.org/10.1042/BCJ20210459

Published: 14 October 2021

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Crystallographic approach to fragment-based hit discovery against Schistosoma mansoni purine nucleoside phosphorylase

Muhammad Faheem, Napoleão Fonseca Valadares, José Brandão-Neto, Dom Bellini, Patrick Collins, Nicholas M. Pearce, Louise Bird, Juliana Roberta Torini, Raymond Owens, Humberto DMuniz Pereira, Frank Von Delft, João Alexandre Ribeiro Gonçalves Barbosa

Biochem J (2021) 478 (19): 3655–3670.

DOI: https://doi.org/10.1042/BCJ20210041

Published: 14 October 2021

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Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen

Jennifer M. Crowther, Letitia H. Gilmour, Benjamin T. Porebski, Sarah G. Heath, Neil R. Pattinson, Maurice C. Owen, Rayleen Fredericks, Ashley M. Buckle, Conan J. Fee, Christoph Göbl, Renwick C. J. Dobson

Biochem J (2021) 478 (17): 3319–3330.

DOI: https://doi.org/10.1042/BCJ20210476

Published: 14 September 2021

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Electron inventory of the iron-sulfur scaffold complex HypCD essential in [NiFe]-hydrogenase cofactor assembly

Sven T. Stripp, Jonathan Oltmanns, Christina S. Müller, David Ehrenberg, Ramona Schlesinger, Joachim Heberle, Lorenz Adrian, Volker Schünemann, Antonio J. Pierik, Basem Soboh

Biochem J (2021) 478 (17): 3281–3295.

DOI: https://doi.org/10.1042/BCJ20210224

Published: 07 September 2021

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The kinetics of islet amyloid polypeptide phase-separated system and hydrogel formation are critically influenced by macromolecular crowding

Lior Pytowski, David J. Vaux, Létitia Jean

Biochem J (2021) 478 (15): 3025–3046.

DOI: https://doi.org/10.1042/BCJ20210384

Published: 13 August 2021

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Per aspera ad chaos : a personal journey to the wonderland of intrinsic disorder

Vladimir N. Uversky

Biochem J (2021) 478 (15): 3015–3024.

DOI: https://doi.org/10.1042/BCJ20210146

Published: 10 August 2021

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The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands

Neda S. Kazemein Jasemi, Christian Herrmann, Eva Magdalena Estirado, Lothar Gremer, Dieter Willbold, Luc Brunsveld, Radovan Dvorsky, Mohammad R. Ahmadian

Biochem J (2021) 478 (14): 2793–2809.

DOI: https://doi.org/10.1042/BCJ20210105

Published: 23 July 2021

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Mapping the interaction surface of scorpion β-toxins with an insect sodium channel

Boris S. Zhorov, Yuzhe Du, Weizhong Song, Ningguang Luo, Dalia Gordon, Michael Gurevitz, Ke Dong

Biochem J (2021) 478 (14): 2843–2869.

DOI: https://doi.org/10.1042/BCJ20210336

Published: 23 July 2021

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Rational design of electron/proton transfer mechanisms in the exoelectrogenic bacteria Geobacter sulfurreducens

Marta A. Silva, Pilar C. Portela, Carlos A. Salgueiro

Biochem J (2021) 478 (14): 2871–2887.

DOI: https://doi.org/10.1042/BCJ20210365

Published: 23 July 2021

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Conformational plasticity of the ULK3 kinase domain

Sebastian Mathea, Eidarus Salah, Cynthia Tallant, Deep Chatterjee, Benedict-Tilman Berger, Rebecca Konietzny, Susanne Müller, Benedikt M. Kessler, Stefan Knapp

Biochem J (2021) 478 (14): 2811–2823.

DOI: https://doi.org/10.1042/BCJ20210257

Published: 23 July 2021

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Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha

Hamine C. de Oliveira, Tainá D. da Silva, Guilherme H. M. Salvador, Ivan R. Moraes, Cíntia A. Fukuda, Andrea C. de Barros, Marcos R. M. Fontes

Biochem J (2021) 478 (13): 2715–2732.

DOI: https://doi.org/10.1042/BCJ20210401

Published: 16 July 2021

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The interplay of self-assembly and target binding in centrin 1 from Toxoplasma gondii

Carolina Conter, Luca Bombardi, Marco Pedretti, Filippo Favretto, Adele Di Matteo, Paola Dominici, Alessandra Astegno

Biochem J (2021) 478 (13): 2571–2587.

DOI: https://doi.org/10.1042/BCJ20210295

Published: 09 July 2021

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Aberrant environment and PS-binding to calnuc C-terminal tail drives exosomal packaging and its metastatic ability

Ravichandran Vignesh, Anita Sjölander, Ganesh Venkatraman, Suresh Kumar Rayala, Gopala Krishna Aradhyam

Biochem J (2021) 478 (12): 2265–2283.

DOI: https://doi.org/10.1042/BCJ20210016

Published: 18 June 2021

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Kinetics of the multitasking high-affinity Win binding site of WDR5 in restricted and unrestricted conditions

Ali Imran, Brandon S. Moyer, Ashley J. Canning, Dan Kalina, Thomas M. Duncan, Kelsey J. Moody, Aaron J. Wolfe, Michael S. Cosgrove, Liviu Movileanu

Biochem J (2021) 478 (11): 2145–2161.

DOI: https://doi.org/10.1042/BCJ20210253

Published: 11 June 2021

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On the specificity of protein–protein interactions in the context of disorder

Kaare Teilum, Johan G. Olsen, Birthe B. Kragelund

Biochem J (2021) 478 (11): 2035–2050.

DOI: https://doi.org/10.1042/BCJ20200828

Published: 08 June 2021

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Conformational changes during the reaction cycle of plasma membrane Ca 2+ -ATPase in the autoinhibited and activated states

Nicolás A. Saffioti, Marilina de Sautu, Ana Sol Riesco, Mariela S. Ferreira-Gomes, Juan Pablo F. C. Rossi, Irene C. Mangialavori

Biochem J (2021) 478 (10): 2019–2034.

DOI: https://doi.org/10.1042/BCJ20210036

Published: 28 May 2021

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The breakthrough in protein structure prediction

Andrei N. Lupas, Joana Pereira, Vikram Alva, Felipe Merino, Murray Coles, Marcus D. Hartmann

Biochem J (2021) 478 (10): 1885–1890.

DOI: https://doi.org/10.1042/BCJ20200963

Published: 24 May 2021

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Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4

Hunmin Jung, Seongmin Lee

Biochem J (2021) 478 (9): 1769–1781.

DOI: https://doi.org/10.1042/BCJ20210162

Published: 10 May 2021

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Synergy and allostery in ligand binding by HIV-1 Nef

Abdullah Aldehaiman, Afaque A. Momin, Audrey Restouin, Luyao Wang, Xiaoli Shi, Safia Aljedani, Sandrine Opi, Adrien Lugari, Umar F. Shahul Hameed, Luc Ponchon, Xavier Morelli, Mingdong Huang, Christian Dumas, Yves Collette, Stefan T. Arold

Biochem J (2021) 478 (8): 1525–1545.

DOI: https://doi.org/10.1042/BCJ20201002

Published: 21 April 2021

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Excitation energy transfer kinetics of trimeric, monomeric and subunit-depleted Photosystem I from Synechocystis PCC 6803

Parveen Akhtar, Avratanu Biswas, László Kovács, Nathan Nelson, Petar H. Lambrev

Biochem J (2021) 478 (7): 1333–1346.

DOI: https://doi.org/10.1042/BCJ20210021

Published: 06 April 2021

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Tracking biochemical changes induced by iron loading in AML12 cells with synchrotron live cell, time-lapse infrared microscopy

Clinton J. Kidman, Cyril D.S. Mamotte, M. Adrien Eynaud, Juliane Reinhardt, Jitraporn Vongsvivut, Mark J. Tobin, Mark J. Hackett, Ross M. Graham

Biochem J (2021) 478 (6): 1227–1239.

DOI: https://doi.org/10.1042/BCJ20200653

Published: 19 March 2021

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Elucidating the role of GRIM-19 as a substrate and allosteric activator of pro-apoptotic serine protease HtrA2

Raghupathi Kummari, Shubhankar Dutta, Shubhangi Patil, Snehal Pandav Mudrale, Kakoli Bose

Biochem J (2021) 478 (6): 1241–1259.

DOI: https://doi.org/10.1042/BCJ20200923

Published: 19 March 2021

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Structural insights into histone chaperone Asf1 and its characterization from Plasmodium falciparum

Dushyant Kumar Srivastava, Sarika Gunjan, Chandrima Das, Vasudevan Seshadri, Siddhartha Roy

Biochem J (2021) 478 (5): 1117–1136.

DOI: https://doi.org/10.1042/BCJ20200891

Published: 10 March 2021

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Structural basis of a chemokine heterodimer binding to glycosaminoglycans

Krishna Mohan Sepuru, Krishna Rajarathnam

Biochem J (2021) 478 (5): 1009–1021.

DOI: https://doi.org/10.1042/BCJ20200927

Published: 04 March 2021

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Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps

Hideaki Sato, Masakazu Sugishima, Mai Tsukaguchi, Takahiro Masuko, Mikuru Iijima, Mitsunori Takano, Yoshiaki Omata, Kei Hirabayashi, Kei Wada, Yoshio Hisaeda, Ken Yamamoto

Biochem J (2021) 478 (5): 1023–1042.

DOI: https://doi.org/10.1042/BCJ20200996

Published: 04 March 2021

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