1-13 of 13
Patrick A. Eyers
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E. Eyers, Natarajan Kannan, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2023) 480 (2): 141–160.
DOI: https://doi.org/10.1042/BCJ20220474
Published: 23 January 2023
View article
PDF
Includes: Multimedia, Supplementary data
Articles

Correction: Mobility shift-based electrophoresis coupled with fluorescent detection enables real-time enzyme analysis of carbohydrate sulfatase activity

Dominic P. Byrne, James A. London, Patrick A. Eyers, Edwin A. Yates, Alan Cartmell
Journal: Biochemical Journal
Biochem J (2021) 478 (13): 2537–2538.
DOI: https://doi.org/10.1042/BCJ-2020-0952_COR
Published: 02 July 2021
View article
PDF
Articles

Mobility shift-based electrophoresis coupled with fluorescent detection enables real-time enzyme analysis of carbohydrate sulfatase activity

Dominic P. Byrne, James A. London, Patrick A. Eyers, Edwin A. Yates, Alan Cartmell
Journal: Biochemical Journal
Biochem J (2021) 478 (4): 735–748.
DOI: https://doi.org/10.1042/BCJ20200952
Published: 18 February 2021
View article
PDF
Articles

Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics

Dominic P. Byrne, Christopher J. Clarke, Philip J. Brownridge, Anton Kalyuzhnyy, Simon Perkins, Amy Campbell, David Mason, Andrew R. Jones, Patrick A. Eyers, Claire E. Eyers
Journal: Biochemical Journal
Biochem J (2020) 477 (13): 2451–2475.
DOI: https://doi.org/10.1042/BCJ20200309
Published: 02 July 2020
View article
PDF
Includes: Supplementary data
Articles

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

In Collection
Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
Dominic P. Byrne, Yong Li, Pawin Ngamlert, Krithika Ramakrishnan, Claire E. Eyers, Carrow Wells, David H. Drewry, William J. Zuercher, Neil G. Berry, David G. Fernig, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2018) 475 (15): 2435–2455.
DOI: https://doi.org/10.1042/BCJ20180266
Published: 14 August 2018
View article
PDF
Includes: Supplementary data
Articles

New tools for carbohydrate sulfation analysis: heparan sulfate 2- O -sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

Dominic P. Byrne, Yong Li, Krithika Ramakrishnan, Igor L. Barsukov, Edwin A. Yates, Claire E. Eyers, Dulcé Papy-Garcia, Sandrine Chantepie, Vijayakanth Pagadala, Jian Liu, Carrow Wells, David H. Drewry, William J. Zuercher, Neil G. Berry, David G. Fernig, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2018) 475 (15): 2417–2433.
DOI: https://doi.org/10.1042/BCJ20180265
Published: 14 August 2018
View article
PDF
Includes: Supplementary data
Articles

Back to the future: new target-validated Rab antibodies for evaluating LRRK2 signalling in cell biology and Parkinson's disease

Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2018) 475 (1): 185–189.
DOI: https://doi.org/10.1042/BCJ20170870
Published: 05 January 2018
View article
PDF
Articles

cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility–mass spectrometry

Dominic P. Byrne, Matthias Vonderach, Samantha Ferries, Philip J. Brownridge, Claire E. Eyers, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2016) 473 (19): 3159–3175.
DOI: https://doi.org/10.1042/BCJ20160648
Published: 27 September 2016
View article
PDF
Includes: Supplementary data
Articles

‘Up with the LRRK’: a phosphorylated Rab10 assay for evaluation of LRRK2 activity and inhibitor engagement

Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2016) 473 (18): 2757–2762.
DOI: https://doi.org/10.1042/BCJ20160671C
Published: 12 September 2016
View article
PDF
Articles

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner

Fiona P. Bailey, Dominic P. Byrne, Krishnadev Oruganty, Claire E. Eyers, Christopher J. Novotny, Kevan M. Shokat, Natarajan Kannan, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2015) 467 (1): 47–62.
DOI: https://doi.org/10.1042/BJ20141441
Published: 20 March 2015
View article
PDF
Includes: Supplementary data
Articles

Going for broke: targeting the human cancer pseudokinome

Fiona P. Bailey, Dominic P. Byrne, Daniel McSkimming, Natarajan Kannan, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2015) 465 (2): 195–211.
DOI: https://doi.org/10.1042/BJ20141060
Published: 06 January 2015
View article
PDF
Articles

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

James M. Murphy, Qingwei Zhang, Samuel N. Young, Michael L. Reese, Fiona P. Bailey, Patrick A. Eyers, Daniela Ungureanu, Henrik Hammaren, Olli Silvennoinen, Leila N. Varghese, Kelan Chen, Anne Tripaydonis, Natalia Jura, Koichi Fukuda, Jun Qin, Zachary Nimchuk, Mary Beth Mudgett, Sabine Elowe, Christine L. Gee, Ling Liu, Roger J. Daly, Gerard Manning, Jeffrey J. Babon, Isabelle S. Lucet
Journal: Biochemical Journal
Biochem J (2014) 457 (2): 323–334.
DOI: https://doi.org/10.1042/BJ20131174
Published: 20 December 2013
View article
PDF
Includes: Supplementary data
Articles

Phosphoregulation of human Mps1 kinase

Rebecca K. Tyler, Matthew L. H. Chu, Hannah Johnson, Edward A. McKenzie, Simon J. Gaskell, Patrick A. Eyers
Journal: Biochemical Journal
Biochem J (2009) 417 (1): 173–184.
DOI: https://doi.org/10.1042/BJ20081310
Published: 12 December 2008
View article
PDF
Includes: Supplementary data