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Nicole K. Polinski
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Articles

Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms

In Collection
Protein structure and function
Asad U. Malik, Athanasios Karapetsas, Raja S. Nirujogi, Sebastian Mathea, Deep Chatterjee, Prosenjit Pal, Pawel Lis, Matthew Taylor, Elena Purlyte, Robert Gourlay, Mark Dorward, Simone Weidlich, Rachel Toth, Nicole K. Polinski, Stefan Knapp, Francesca Tonelli, Dario R. Alessi
Journal: Biochemical Journal
Biochem J (2021) 478 (3): 553–578.
DOI: https://doi.org/10.1042/BCJ20200937
Published: 10 February 2021
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Includes: Supplementary data
Articles

Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity

Alexia F. Kalogeropulou, Jordana B. Freemantle, Pawel Lis, Edmundo G. Vides, Nicole K. Polinski, Dario R. Alessi
Journal: Biochemical Journal
Biochem J (2020) 477 (22): 4397–4423.
DOI: https://doi.org/10.1042/BCJ20200458
Published: 27 November 2020
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Includes: Supplementary data
Articles

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human

In Collection
Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
Rafeeq Mir, Francesca Tonelli, Pawel Lis, Thomas Macartney, Nicole K. Polinski, Terina N. Martinez, Meng-Yun Chou, Andrew J.M. Howden, Theresa König, Christoph Hotzy, Ivan Milenkovic, Thomas Brücke, Alexander Zimprich, Esther Sammler, Dario R. Alessi
Journal: Biochemical Journal
Biochem J (2018) 475 (11): 1861–1883.
DOI: https://doi.org/10.1042/BCJ20180248
Published: 06 June 2018
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Includes: Supplementary data
Articles

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase

In Collection
Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
Pawel Lis, Sophie Burel, Martin Steger, Matthias Mann, Fiona Brown, Federico Diez, Francesca Tonelli, Janice L. Holton, Philip Winglok Ho, Shu-Leong Ho, Meng-Yun Chou, Nicole K. Polinski, Terina N. Martinez, Paul Davies, Dario R. Alessi
Journal: Biochemical Journal
Biochem J (2018) 475 (1): 1–22.
DOI: https://doi.org/10.1042/BCJ20170802
Published: 02 January 2018
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Includes: Supplementary data