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Leena ALHONEN
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Articles

Controlling of N -alkylpolyamine analogue metabolism by selective deuteration

Sebahat Ucal, Merja R. Häkkinen, Aino-Liisa Alanne, Leena Alhonen, Jouko Vepsäläinen, Tuomo A. Keinänen, Mervi T. Hyvönen
Journal: Biochemical Journal
Biochem J (2018) 475 (3): 663–676.
https://doi.org/10.1042/BCJ20170887
Published: 14 February 2018
View article titled, Controlling of N -alkylpolyamine analogue metabolism by selective deuteration
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Includes: Supplementary data
Articles

Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation

Mervi T. Hyvönen, Sebahat Ucal, Markku Pasanen, Sirpa Peräniemi, Janne Weisell, Maxim Khomutov, Alex R. Khomutov, Jouko Vepsäläinen, Leena Alhonen, Tuomo A. Keinänen
Journal: Biochemical Journal
Biochem J (2016) 473 (10): 1433–1441.
https://doi.org/10.1042/BCJ20160134
Published: 11 May 2016
View article titled, Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation
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Includes: Supplementary data
Articles

Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A

Mervi T. Hyvönen, Taina Koponen, Janne Weisell, Marko Pietilä, Alex R. Khomutov, Jouko Vepsäläinen, Leena Alhonen, Tuomo A. Keinänen
Journal: Biochemical Journal
Biochem J (2013) 453 (3): 467–474.
https://doi.org/10.1042/BJ20130263
Published: 12 July 2013
View article titled, Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A
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Includes: Supplementary data
Articles

Divergent regulation of the key enzymes of polyamine metabolism by chiral α-methylated polyamine analogues

Mervi T. Hyvönen, Michael T. Howard, Christine B. Anderson, Nikolay Grigorenko, Alex R. Khomutov, Jouko Vepsäläinen, Leena Alhonen, Juhani Jänne, Tuomo A. Keinänen
Journal: Biochemical Journal
Biochem J (2009) 422 (2): 321–328.
https://doi.org/10.1042/BJ20090737
Published: 13 August 2009
View article titled, Divergent regulation of the key enzymes of polyamine metabolism by chiral α-methylated polyamine analogues
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Articles

Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts

Anne Uimari, Tuomo A. Keinänen, Anne Karppinen, Patrick Woster, Pekka Uimari, Juhani Jänne, Leena Alhonen
Journal: Biochemical Journal
Biochem J (2009) 422 (1): 101–109.
https://doi.org/10.1042/BJ20090411
Published: 29 July 2009
View article titled, Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts
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Articles

Polyamines are required for the initiation of rat liver regeneration

Leena ALHONEN, Tiina-Liisa RÄSÄNEN, Riitta SINERVIRTA, Jyrki J. PARKKINEN, Veli-Pekka KORHONEN, Marko PIETILÄ, Juhani JÄNNE
Journal: Biochemical Journal
Biochem J (2002) 362 (1): 149–153.
https://doi.org/10.1042/bj3620149
Published: 08 February 2002
View article titled, Polyamines are required for the initiation of rat liver regeneration
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Articles

Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice

Suvikki SUPPOLA, Sami HEIKKINEN, Jyrki J. PARKKINEN, Mikko UUSI-OUKARI, Veli-Pekka KORHONEN, Tuomo KEINÄNEN, Leena ALHONEN, Juhani JÄNNE
Journal: Biochemical Journal
Biochem J (2001) 358 (2): 343–348.
https://doi.org/10.1042/bj3580343
Published: 24 August 2001
View article titled, Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice
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Articles

Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

Suvikki SUPPOLA, Marko PIETILÄ, Jyrki J. PARKKINEN, Veli-Pekka KORHONEN, Leena ALHONEN, Maria HALMEKYTÖ, Carl W. PORTER, Juhani JÄNNE
Journal: Biochemical Journal
Biochem J (1999) 338 (2): 311–316.
https://doi.org/10.1042/bj3380311
Published: 22 February 1999
View article titled, Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue
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Articles

Transgenic mice overexpressing ornithine and S -adenosylmethionine decarboxylases maintain a physiological polyamine homoeostasis in their tissues

Ritva HELJASVAARA, Ildiko VERESS, Maria HALMEKYTÖ, Leena ALHONEN, Juhani JÄNNE, Pasi LAAJALA, Antti PAJUNEN
Journal: Biochemical Journal
Biochem J (1997) 323 (2): 457–462.
https://doi.org/10.1042/bj3230457
Published: 15 April 1997
View article titled, Transgenic mice overexpressing ornithine and S -adenosylmethionine decarboxylases maintain a physiological polyamine homoeostasis in their tissues
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Articles

Transgenic mice expressing the human ornithine decarboxylase gene under the control of mouse metallothionein I promoter

Leena ALHONEN, Sami HEIKKINEN, Riitta SINERVIRTA, Maria HALMEKYTÖ, Pekka ALAKUIJALA, Juhani JÄNNE
Journal: Biochemical Journal
Biochem J (1996) 314 (2): 405–408.
https://doi.org/10.1042/bj3140405
Published: 01 March 1996
View article titled, Transgenic mice expressing the human ornithine decarboxylase gene under the control of mouse metallothionein I promoter
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Articles

Regulation of S -adenosylmethionine decarboxylase by polyamines in Ehrlich ascites-carcinoma cells grown in culture

Leena Alhonen-Hongisto
Journal: Biochemical Journal
Biochem J (1980) 190 (3): 747–754.
https://doi.org/10.1042/bj1900747
Published: 15 September 1980
View article titled, Regulation of S -adenosylmethionine decarboxylase by polyamines in Ehrlich ascites-carcinoma cells grown in culture
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