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F. Anthony LAI
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Articles

Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction

Sahar I. Da'as, Khalid Fakhro, Angelos Thanassoulas, Navaneethakrishnan Krishnamoorthy, Alaaeldin Saleh, Brian L. Calver, Bared Safieh-Garabedian, Egon Toft, George Nounesis, F. Anthony Lai, Michail Nomikos
Journal: Biochemical Journal
Biochem J (2018) 475 (24): 3933–3948.
DOI: https://doi.org/10.1042/BCJ20180685
Published: 14 December 2018
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Includes: Supplementary data
Articles

The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation

Michail Nomikos, Junaid Kashir, F. Anthony Lai
Journal: Biochemical Journal
Biochem J (2017) 474 (21): 3659–3673.
DOI: https://doi.org/10.1042/BCJ20160521
Published: 23 October 2017
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Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ

Michail Nomikos, Panagiotis Stamatiadis, Jessica R. Sanders, Konrad Beck, Brian L. Calver, Luke Buntwal, Morgan Lofty, Zili Sideratou, Karl Swann, F. Anthony Lai
Journal: Biochemical Journal
Biochem J (2017) 474 (6): 1003–1016.
DOI: https://doi.org/10.1042/BCJ20161057
Published: 07 March 2017
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Articles

N-terminus oligomerization is conserved in intracellular calcium release channels

Spyros Zissimopoulos, Jason Marsh, Laurence Stannard, Monika Seidel, F. Anthony Lai
Journal: Biochemical Journal
Biochem J (2014) 459 (2): 265–273.
DOI: https://doi.org/10.1042/BJ20131061
Published: 28 March 2014
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Articles

Novel regulation of PLCζ activity via its XY-linker

Michail Nomikos, Khalil Elgmati, Maria Theodoridou, Athena Georgilis, J. Raul Gonzalez-Garcia, George Nounesis, Karl Swann, F. Anthony Lai
Journal: Biochemical Journal
Biochem J (2011) 438 (3): 427–432.
DOI: https://doi.org/10.1042/BJ20110953
Published: 26 August 2011
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Articles

Divergent effect of mammalian PLCζ in generating Ca 2+ oscillations in somatic cells compared with eggs

Sally V. Phillips, Yuansong Yu, Andreas Rossbach, Michail Nomikos, Vyronia Vassilakopoulou, Evangelia Livaniou, Bevan Cumbes, F. Anthony Lai, Christopher H. George, Karl Swann
Journal: Biochemical Journal
Biochem J (2011) 438 (3): 545–553.
DOI: https://doi.org/10.1042/BJ20101581
Published: 26 August 2011
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Includes: Supplementary data
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Male infertility-linked point mutation disrupts the Ca 2+ oscillation-inducing and PIP 2 hydrolysis activity of sperm PLCζ

Michail Nomikos, Khalil Elgmati, Maria Theodoridou, Brian L. Calver, Bevan Cumbes, Georg Nounesis, Karl Swann, F. Anthony Lai
Journal: Biochemical Journal
Biochem J (2011) 434 (2): 211–217.
DOI: https://doi.org/10.1042/BJ20101772
Published: 11 February 2011
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Articles

FKBP12.6 binding of ryanodine receptors carrying mutations associated with arrhythmogenic cardiac disease

Spyros Zissimopoulos, N. Lowri Thomas, Wan W. Jamaluddin, F. Anthony Lai
Journal: Biochemical Journal
Biochem J (2009) 419 (2): 273–278.
DOI: https://doi.org/10.1042/BJ20082324
Published: 27 March 2009
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Includes: Supplementary data
Articles

Oligomerization of the cardiac ryanodine receptor C-terminal tail

Richard STEWART, Spyros ZISSIMOPOULOS, F. Anthony LAI
Journal: Biochemical Journal
Biochem J (2003) 376 (3): 795–799.
DOI: https://doi.org/10.1042/bj20030597
Published: 15 December 2003
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Articles

In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6

Christopher H. GEORGE, Rina SORATHIA, Benedicte M.A. BERTRAND, F. Anthony LAI
Journal: Biochemical Journal
Biochem J (2003) 370 (2): 579–589.
DOI: https://doi.org/10.1042/bj20021433
Published: 01 March 2003
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Articles

Multiple isoforms of the ryanodine receptor are expressed in rat pancreatic acinar cells

Timothy J. FITZSIMMONS, Ilya GUKOVSKY, James A. McROBERTS, Edward RODRIGUEZ, F. Anthony LAI, Stephen J. PANDOL
Journal: Biochemical Journal
Biochem J (2000) 351 (1): 265–271.
DOI: https://doi.org/10.1042/bj3510265
Published: 26 September 2000
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The soluble sperm factor that causes Ca2+ release from sea-urchin (Lytechinus pictus) egg homogenates also triggers Ca2+ oscillations after injection into mouse eggs

John PARRINGTON, Keith T. JONES, F. Anthony LAI, Karl SWANN
Journal: Biochemical Journal
Biochem J (1999) 341 (1): 1–4.
DOI: https://doi.org/10.1042/bj3410001
Published: 24 June 1999
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Articles

Differential expression and regulation of ryanodine receptor and myo -inositol 1,4,5-trisphosphate receptor Ca 2+ release channels in mammalian tissues and cell lines

John J. MACKRILL, R. A. John CHALLISS, D. A. O'CONNELL, F. Anthony LAI, Stefan R. NAHORSKI
Journal: Biochemical Journal
Biochem J (1997) 327 (1): 251–258.
DOI: https://doi.org/10.1042/bj3270251
Published: 01 October 1997
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Articles

The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis

Richard E. A. TUNWELL, Colin WICKENDEN, Bénédicte M. A. BERTRAND, Valery I. SHEVCHENKO, Martina B. WALSH, Paul D. ALLEN, F. Anthony LAI
Journal: Biochemical Journal
Biochem J (1996) 318 (2): 477–487.
DOI: https://doi.org/10.1042/bj3180477
Published: 01 September 1996
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Articles

A cytosolic sperm factor triggers calcium oscillations in rat hepatocytes

Christopher P. BERRIE, K. S. Roy CUTHBERTSON, J. PARRINGTON, F. Anthony LAI, Karl SWANN
Journal: Biochemical Journal
Biochem J (1996) 313 (2): 369–372.
DOI: https://doi.org/10.1042/bj3130369
Published: 15 January 1996
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