Skip Nav Destination
In this issue Arora and colleagues (pp. 25–39) show that Plasmodium PfUSP is an essential protease for parasite survival, and its inhibition increases the efficacy of artemisinin-based drugs. Therefore, PfUSP can be targeted to develop novel scaffolds for developing new antimalarials to combat artemisinin resistance. The cover image shows fluorescent microscope images of PfUSP transgenic parasites immuno-stained with anti-HA and anti-BiP antibody at different time points in control and iKD sets. This depicts the effect of down-regulation of PfUSP on development of parasite endoplasmic reticulum. The image is courtesy of Asif Mohmmed.
In this Issue
Characterizing crosstalk in epigenetic signaling to understand disease physiology
Biochem J (2023) 480 (1): 57–85.
A Plasmodium falciparum ubiquitin-specific protease (PfUSP) is essential for parasite survival and its disruption enhances artemisinin efficacy
Biochem J (2023) 480 (1): 25–39.
Construction of mouse cochlin mutants with different GAG-binding specificities and their use for immunohistochemistry
Karin Murakami; Ryo Tamura; Sanae Ikehara; Hayato Ota; Tomomi Ichimiya; Naoki Matsumoto; Hisahiro Matsubara; Shoko Nishihara; Yuzuru Ikehara; Kazuo Yamamoto
Biochem J (2023) 480 (1): 41–56.
The atypical thioredoxin ‘Alr2205’, a newly identified partner of the typical 2-Cys-Peroxiredoxin, safeguards the cyanobacterium Anabaena from oxidative stress
Manisha Banerjee; Namrata Waghamare; Prakash Kalwani; Deepak T. Hurali; Rachna Agarwal; Anand Ballal
Biochem J (2023) 480 (1): 87–104.