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Issues
February 2022
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Cover Image
Cover Image
Immunofluorescence staining of WT, IKKα KO, IKKβ KO and IKKα/β DKO HCT116 cells with anti-p65 NF-kB antibody (green); nuclei stained with DAPI (blue) by Jack Prescott. This figure demonstrates a critical role for IKKα in TNFα-induced p65 nuclear translocation with only a minor role for IKKβ.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Perspective
Review Articles
Systems approaches to understand oxygen sensing: how multi-omics has driven advances in understanding oxygen-based signalling
Biochem J (2022) 479 (3): 245–257.
Research Articles
Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation
Rayner M. L. Queiroz; Siân C. Piper; Johanna S. Rees; Sam Strickson; Emmanuel Briend; Choon Pei Low; G. John Ferguson; Kathryn S. Lilley; Antony P. Jackson; Donna K. Finch
Biochem J (2022) 479 (3): 225–243.
TAT–RHIM: a more complex issue than expected
Benedikt Kolbrink; Theresa Riebeling; Nikolas K. Teiwes; Claudia Steinem; Hubert Kalbacher; Ulrich Kunzendorf; Stefan Krautwald
Biochem J (2022) 479 (3): 259–272.
IKKα plays a major role in canonical NF-κB signalling in colorectal cells
Biochem J (2022) 479 (3): 305–325.
N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum
Biochem J (2022) 479 (3): 337–356.
APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells
Biochem J (2022) 479 (3): 385–399.
Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo
Angela Clerk; Daniel N. Meijles; Michelle A. Hardyman; Stephen J. Fuller; Sonia P. Chothani; Joshua J. Cull; Susanna T.E. Cooper; Hajed O. Alharbi; Konstantinos Vanezis; Leanne E. Felkin; Thomais Markou; Samuel J. Leonard; Spencer W. Shaw; Owen J.L. Rackham; Stuart A. Cook; Peter E. Glennon; Mary N. Sheppard; John C. Sembrat; Mauricio Rojas; Charles F. McTiernan; Paul J. Barton; Peter H. Sugden
Biochem J (2022) 479 (3): 401–424.
Differential effect of canagliflozin, a sodium–glucose cotransporter 2 (SGLT2) inhibitor, on slow and fast skeletal muscles from nondiabetic mice
Hiroko Otsuka; Hisashi Yokomizo; Shintaro Nakamura; Yoshihiro Izumi; Masatomo Takahashi; Sachiko Obara; Motonao Nakao; Yosuke Ikeda; Naoichi Sato; Ryuichi Sakamoto; Yasutaka Miyachi; Takashi Miyazawa; Takeshi Bamba; Yoshihiro Ogawa
Biochem J (2022) 479 (3): 425–444.
