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Issues
September 2020
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Cover Image
Cover Image
The cover image is of a molecularly modelled receptor heterodimeric complex in its ligand bound active state (left), juxtaposed to uncomplexed receptors (right) in the presence of the proof of concept inhibitor which prevents ligand bound complex formation. For more information, see the article by Colomba and colleagues (pp. 3329–3347). The image was created by Phospho Biomedical Animation and provided by Peter Parker.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products
Biochem J (2020) 477 (17): 3349–3366.
Mechanistic and structural insights into histone H2A–H2B chaperone in chromatin regulation
Biochem J (2020) 477 (17): 3367–3386.
Research Articles
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression
Ezequiel J. Tolosa; Maite G. Fernandez-Barrena; Eriko Iguchi; Angela L. McCleary-Wheeler; Ryan M. Carr; Luciana L. Almada; Luis F. Flores; Renzo E. Vera; Germine W. Alfonse; David L. Marks; Tara L. Hogenson; Anne M. Vrabel; Isaac P. Horn; Amanda N. Koenig; Stephanie L. Safgren; Ashley N. Sigafoos; Mert Erkan; Paola A. Romecin-Duran; Alejandro Sarabia Gonzalez; Bo Zhou; Delphine Javelaud; Veronique Marsaud; Rondell P. Graham; Alain Mauviel; Sherine F. Elsawa; Martin E. Fernandez-Zapico
Biochem J (2020) 477 (17): 3131–3145.
Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function
Michelle C. Miller; Irina V. Nesmelova; Vladimir A. Daragan; Hans Ippel; Malwina Michalak; Aurelio Dregni; Herbert Kaltner; Jürgen Kopitz; Hans-Joachim Gabius; Kevin H. Mayo
Biochem J (2020) 477 (17): 3147–3165.
Characterization of the different oligomeric states of the DAN family antagonists SOSTDC1 and SOST
Biochem J (2020) 477 (17): 3167–3182.
Functional role of TRPC6 and STIM2 in cytosolic and endoplasmic reticulum Ca2+ content in resting estrogen receptor-positive breast cancer cells
Jose Sanchez-Collado; Jose J. Lopez; Lucia Gonzalez-Gutierrez; Carlos Cantonero; Isaac Jardin; Ginés M. Salido; Juan A. Rosado
Biochem J (2020) 477 (17): 3183–3197.
Identifying key residues and key interactions for the binding of LEAP2 to receptor GHSR1a
Biochem J (2020) 477 (17): 3199–3217.
Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody
Caroline Soliman; Andrew J. Guy; Jia Xin Chua; Mireille Vankemmelbeke; Richard S. McIntosh; Sarah Eastwood; Vi Khanh Truong; Aaron Elbourne; Ian Spendlove; Lindy G. Durrant; Paul A. Ramsland
Biochem J (2020) 477 (17): 3219–3235.
Source of 12C in Calvin–Benson cycle intermediates and isoprene emitted from plant leaves fed with 13CO2
Biochem J (2020) 477 (17): 3237–3252.
The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
Hunmin Jung; Tomomi Takeshima; Tsutomu Nakagawa; Karen S. MacMillan; R. Max Wynn; Hanzhi Wang; Haruhiko Sakiyama; Shuguang Wei; Yang Li; Richard K. Bruick; Bruce A. Posner; Jef K. De Brabander; Kosaku Uyeda
Biochem J (2020) 477 (17): 3253–3269.
Crystal structure of an insect antifreeze protein reveals ordered waters on the ice-binding surface
Biochem J (2020) 477 (17): 3271–3286.
The structural basis of Bcl-2 mediated cell death regulation in hydra
Biochem J (2020) 477 (17): 3287–3297.
Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice
Biochem J (2020) 477 (17): 3313–3327.
A small molecule inhibitor of HER3: a proof-of-concept study
Audrey Colomba; Martina Fitzek; Roger George; Gregory Weitsman; Selene Roberts; Laura Zanetti-Domingues; Michael Hirsch; Daniel J. Rolfe; Shahid Mehmood; Andrew Madin; Jeroen Claus; Svend Kjaer; Ambrosius P. Snijders; Tony Ng; Marisa Martin-Fernandez; David M. Smith; Peter J. Parker
Biochem J (2020) 477 (17): 3329–3347.
Sunitinib inhibits RNase L by destabilizing its active dimer conformation
Jinle Tang; Yingjie Wang; Huan Zhou; Yuxin Ye; Manisha Talukdar; Ziyang Fu; Zhihong Liu; Jihui Li; Dante Neculai; Jiali Gao; Hao Huang
Biochem J (2020) 477 (17): 3387–3399.
Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation
Andrea Ghiroldi; Marco Piccoli; Pasquale Creo; Federica Cirillo; Paola Rota; Sara D'Imperio; Giuseppe Ciconte; Michelle M. Monasky; Emanuele Micaglio; Andrea Garatti; Massimo Aureli; Emma Veronica Carsana; Lorenzo Menicanti; Carlo Pappone; Luigi Anastasia
Biochem J (2020) 477 (17): 3401–3415.
Degradation of mitochondrial alternative oxidase in the appendices of Arum maculatum
Kikukatsu Ito; Takafumi Ogata; Takanari Seito; Yui Umekawa; Yusuke Kakizaki; Hiroshi Osada; Anthony L. Moore
Biochem J (2020) 477 (17): 3417–3431.
Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate
Christof Trabszo; Bastian Ramms; Pradeep Chopra; Renate Lüllmann-Rauch; Stijn Stroobants; Jens Sproß; Anke Jeschke; Thorsten Schinke; Geert-Jan Boons; Jeffrey D. Esko; Torben Lübke; Thomas Dierks
Biochem J (2020) 477 (17): 3433–3451.
