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Issues
December 2019
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Cover Image
Cover Image
In this issue Dindo and colleagues (pp. 3751–3768) have investigated the interaction of wild-type peroxisomal alanine:glyoxylate aminotransferase (AGT) and the pathogenic G41R variant with d-cycloserine (DCS), a natural product used as a second-line treatment of multidrug-resistant tuberculosis, and its synthetic enantiomer l-cycloserine (LCS). The cover figure shows crystallographic analysis of AGT interaction with LCS and DCS. Image courtesy of Barbara Cellini.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Research Articles
Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia
Aphrodite T. Choumessi; Manuel Johanns; Claire Beaufay; Marie-France Herent; Vincent Stroobant; Didier Vertommen; Cyril Corbet; Roxane Jacobs; Gaëtan Herinckx; Gregory R. Steinberg; Olivier Feron; Joëlle Quetin-Leclercq; Mark H. Rider
Biochem J (2019) 476 (24): 3687–3704.
Copper-dependent ATP7B up-regulation drives the resistance of TMEM16A-overexpressing head-and-neck cancer models to platinum toxicity
Biochem J (2019) 476 (24): 3705–3719.
Characterization of glycerophosphodiesterase 4-interacting molecules Gαq/11 and Gβ, which mediate cellular lysophospholipase D activity
Biochem J (2019) 476 (24): 3721–3736.
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators
Biochem J (2019) 476 (24): 3737–3750.
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1
Mirco Dindo; Silvia Grottelli; Giannamaria Annunziato; Giorgio Giardina; Marco Pieroni; Gioena Pampalone; Andrea Faccini; Francesca Cutruzzolà; Paola Laurino; Gabriele Costantino; Barbara Cellini
Biochem J (2019) 476 (24): 3751–3768.
Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice
Alessandro G. Salerno; Thiago Rentz; Gabriel G. Dorighello; Ana Carolina Marques; Estela Lorza-Gil; Amarylis C. B. A. Wanschel; Audrey de Moraes; Anibal E. Vercesi; Helena C. F. Oliveira
Biochem J (2019) 476 (24): 3769–3789.
Distinct roles of XRCC1 in genome integrity in Xenopus egg extracts
Biochem J (2019) 476 (24): 3791–3804.
Mechanism of protein cleavage at asparagine leading to protein–protein cross-links
Biochem J (2019) 476 (24): 3817–3834.
Insights into the biochemical and functional characterization of sortase E transpeptidase of Corynebacterium glutamicum
Biochem J (2019) 476 (24): 3835–3847.
