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Volume 461, Issue 2

July 2014

All Issues

Cover Image

Cover Image
Front Matter
Table of Contents
Editorial Board

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Review articles
Research articles
Retractions

Review articles

Inositol lipid phosphatases in membrane trafficking and human disease

Peter G. Billcliff; Martin Lowe

Biochem J (2014) 461 (2): 159–175.

Abstract

View Articletitled, Inositol lipid phosphatases in membrane trafficking and human disease

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Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity

Sandra Galic; Nirupa Sachithanandan; Thomas W. Kay; Gregory R. Steinberg

Biochem J (2014) 461 (2): 177–188.

Abstract

View Articletitled, Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity

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Research articles

Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production

Neha Singhal; Atul; Babu S. Mastan; Kota Arun Kumar; Puran Singh Sijwali

Biochem J (2014) 461 (2): 189–203.

Abstracts

View Articletitled, Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production

Supplementary data

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Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism

Nafisa M. Jadavji; Renata H. Bahous; Liyuan Deng; Olga Malysheva; Marilyn Grand’maison; Barry J. Bedell; Marie A. Caudill; Rima Rozen

Biochem J (2014) 461 (2): 205–212.

Abstracts

View Articletitled, Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism

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Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site

Yoel A. Klug; Avraham Ashkenazi; Mathias Viard; Ziv Porat; Robert Blumenthal; Yechiel Shai

Biochem J (2014) 461 (2): 213–222.

Abstracts

View Articletitled, Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site

Supplementary data

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Mitochondrial–nuclear genome interactions in non-alcoholic fatty liver disease in mice

Angela M. Betancourt; Adrienne L. King; Jessica L. Fetterman; Telisha Millender-Swain; Rachel D. Finley; Claudia R. Oliva; David R. Crowe; Scott W. Ballinger; Shannon M. Bailey

Biochem J (2014) 461 (2): 223–232.

Abstracts

View Articletitled, Mitochondrial–nuclear genome interactions in non-alcoholic fatty liver disease in mice

Supplementary data

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Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1β^MYPT1 phosphatase complex and the SCF^βTrCP E3 ubiquitin ligase

Sourav Banerjee; Anna Zagórska; Maria Deak; David G. Campbell; Alan R. Prescott; Dario R. Alessi

Biochem J (2014) 461 (2): 233–245.

Abstracts

View Articletitled, Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase

Supplementary data

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Conserved residues that modulate protein trans-splicing of Npu DnaE split intein

Qin Wu; Zengqiang Gao; Yong Wei; Guolin Ma; Yuchuan Zheng; Yuhui Dong; Yangzhong Liu

Biochem J (2014) 461 (2): 247–255.

Abstracts

View Articletitled, Conserved residues that modulate protein trans-splicing of Npu DnaE split intein

Supplementary data

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The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications

Gilles Flouriot; Guillaume Huet; Florence Demay; Farzad Pakdel; Noureddine Boujrad; Denis Michel

Biochem J (2014) 461 (2): 257–268.

Abstracts

View Articletitled, The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications

Supplementary data

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Detergent-free purification of ABC (ATP-binding-cassette) transporters

Sonali Gulati; Mohammed Jamshad; Timothy J. Knowles; Kerrie A. Morrison; Rebecca Downing; Natasha Cant; Richard Collins; Jan B. Koenderink; Robert C. Ford; Michael Overduin; Ian D. Kerr; Timothy R. Dafforn; Alice J. Rothnie

Biochem J (2014) 461 (2): 269–278.

Abstracts

View Articletitled, Detergent-free purification of ABC (ATP-binding-cassette) transporters

Supplementary data

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Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise

Andreas Flütsch; Rafael Ackermann; Thilo Schroeder; Maria Lukarska; Georg J. Hausammann; Christopher Weinert; Christophe Briand; Markus G. Grütter

Biochem J (2014) 461 (2): 279–290.

Abstracts

View Articletitled, Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise

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Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK–TssFG subcomplex

Grant English; Olwyn Byron; Francesca R. Cianfanelli; Alan R. Prescott; Sarah J. Coulthurst

Biochem J (2014) 461 (2): 291–304.

Abstracts

View Articletitled, Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK–TssFG subcomplex

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Prediction of high- and low-affinity quinol-analogue-binding sites in the aa₃ and bo₃ terminal oxidases from Bacillus subtilis and Escherichia coli

Fabrizio Bossis; Anna De Grassi; Luigi Leonardo Palese; Ciro Leonardo Pierri

Biochem J (2014) 461 (2): 305–314.

Abstracts

View Articletitled, Prediction of high- and low-affinity quinol-analogue-binding sites in the aa3 and bo3 terminal oxidases from Bacillus subtilis and Escherichia coli

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NRBF2 regulates macroautophagy as a component of Vps34 Complex I

Yanyan Cao; Yichen Wang; Widian F. Abi Saab; Fajun Yang; Jeffrey E. Pessin; Jonathan M. Backer

Biochem J (2014) 461 (2): 315–322.

Abstracts

View Articletitled, NRBF2 regulates macroautophagy as a component of Vps34 Complex I

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Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques

Xiaoying Koh-Stenta; Joma Joy; Anders Poulsen; Rong Li; Yvonne Tan; Yoonjung Shim; Jung-Hyun Min; Liling Wu; Anna Ngo; Jianhe Peng; Wei Guang Seetoh; Jing Cao; John Liang Kuan Wee; Perlyn Zekui Kwek; Alvin Hung; Umayal Lakshmanan; Horst Flotow; Ernesto Guccione; Jeffrey Hill

Biochem J (2014) 461 (2): 323–334.

Abstracts

View Articletitled, Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques

Supplementary data

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Structural insights into the substrate-binding mechanism for a novel chitosanase

Qianqian Lyu; Song Wang; Wenhua Xu; Baoqin Han; Wanshun Liu; David N. M. Jones; Weizhi Liu

Biochem J (2014) 461 (2): 335–345.

Abstracts

View Articletitled, Structural insights into the substrate-binding mechanism for a novel chitosanase

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Retractions

Phosphorylation of Ser¹⁵⁸ regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activity

H. Guo; C. Gao; Z. Mi; P. Y. Wai; P. C. Kuo

Biochem J (2014) 461 (2): 347.

Extract

View Articletitled, Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activity

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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria

AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Activin E is a transforming growth factor β ligand that signals specifically through activin receptor-like kinase 7

Correction: Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition

Expression of Concern: Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway

Review articles

Inositol lipid phosphatases in membrane trafficking and human disease

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity

Research articles

Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production

Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism

Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site

Mitochondrial–nuclear genome interactions in non-alcoholic fatty liver disease in mice

Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1β^MYPT1 phosphatase complex and the SCF^βTrCP E3 ubiquitin ligase

Conserved residues that modulate protein trans-splicing of Npu DnaE split intein

The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications

Detergent-free purification of ABC (ATP-binding-cassette) transporters

Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise

Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK–TssFG subcomplex

Prediction of high- and low-affinity quinol-analogue-binding sites in the aa₃ and bo₃ terminal oxidases from Bacillus subtilis and Escherichia coli

NRBF2 regulates macroautophagy as a component of Vps34 Complex I

Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques

Structural insights into the substrate-binding mechanism for a novel chitosanase

Retractions

Phosphorylation of Ser¹⁵⁸ regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activity

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