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Volume 454, Issue 1

August 2013

All Issues

Cover Image

Cover Image
Front Matter
Table of Contents
Editorial Board

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Review articles
Research articles
Correction articles

Review articles

Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes

Robert Stöhr; Massimo Federici

Biochem J (2013) 454 (1): 1–11.

Abstract

View Articletitled, Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes

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SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions

Peter H. Sugden; Liam J. McGuffin; Angela Clerk

Biochem J (2013) 454 (1): 13–30.

Abstract

View Articletitled, SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions

Supplementary data

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Research articles

Vesicular uptake of N-acetylaspartylglutamate is catalysed by sialin (SLC17A5)

Julia Lodder-Gadaczek; Volkmar Gieselmann; Matthias Eckhardt

Biochem J (2013) 454 (1): 31–38.

Abstract

View Articletitled, Vesicular uptake of N-acetylaspartylglutamate is catalysed by sialin (SLC17A5)

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Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif

Jianchuan Wang; Chen Zhong; Fang Wang; Fangfang Qu; Jianping Ding

Biochem J (2013) 454 (1): 39–47.

Abstract

View Articletitled, Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif

Supplementary data

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Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Jonathan H. Clarke; Robin F. Irvine

Biochem J (2013) 454 (1): 49–57.

Abstract

View Articletitled, Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Supplementary data

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Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3

Cheng Dong; Heng Zhang; Zeng-Qiang Gao; Wen-Jia Wang; Zhun She; Guang-Feng Liu; Yue-Quan Shen; Xiao-Dong Su; Yu-Hui Dong

Biochem J (2013) 454 (1): 59–68.

Abstract

View Articletitled, Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3

Supplementary data

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Trafficking defects in PAS domain mutant K_v11.1 channels: roles of reduced domain stability and altered domain–domain interactions

Ying Ke; Chai Ann Ng; Mark J. Hunter; Stefan A. Mann; Juliane Heide; Adam P. Hill; Jamie I. Vandenberg

Biochem J (2013) 454 (1): 69–77.

Abstract

View Articletitled, Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain–domain interactions

Supplementary data

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The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53–N-WASP interaction in epithelial cells

Sun Young Oh; Erik H. Knelson; Gerard C. Blobe; Karthikeyan Mythreye

Biochem J (2013) 454 (1): 79–89.

Abstract

View Articletitled, The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53–N-WASP interaction in epithelial cells

Supplementary data

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Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate

Alla Fridman; Arindam Saha; Adriano Chan; Darren E. Casteel; Renate B. Pilz; Gerry R. Boss

Biochem J (2013) 454 (1): 91–99.

Abstract

View Articletitled, Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate

Supplementary data

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Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits

Ahmed Al-Sabi; Seshu Kumar Kaza; J. Oliver Dolly; Jiafu Wang

Biochem J (2013) 454 (1): 101–108.

Abstract

View Articletitled, Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits

Supplementary data

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CD25 and CD69 induction by α4β1 outside-in signalling requires TCR early signalling complex proteins

Ann-Marie Cimo; Zamal Ahmed; Bradley W. McIntyre; Dorothy E. Lewis; John E. Ladbury

Biochem J (2013) 454 (1): 109–121.

Abstract

View Articletitled, CD25 and CD69 induction by α4β1 outside-in signalling requires TCR early signalling complex proteins

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The CPVT-associated RyR2 mutation G230C enhances store overloadinduced Ca²⁺ release and destabilizes the N-terminal domains

Yingjie Liu; Lynn Kimlicka; Florian Hiess; Xixi Tian; Ruiwu Wang; Lin Zhang; Peter P. Jones; Filip Van Petegem; S. R. Wayne Chen

Biochem J (2013) 454 (1): 123–131.

Abstract

View Articletitled, The CPVT-associated RyR2 mutation G230C enhances store overloadinduced Ca2+ release and destabilizes the N-terminal domains

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Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes

Satomi Nadanaka; Shoji Kagiyama; Hiroshi Kitagawa

Biochem J (2013) 454 (1): 133–145.

Abstract

View Articletitled, Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes

Supplementary data

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Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

Nataliya V. Dolgova; Sergiy Nokhrin; Corey H. Yu; Graham N. George; Oleg Y. Dmitriev

Biochem J (2013) 454 (1): 147–156.

Abstract

View Articletitled, Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

Supplementary data

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Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the α/β hydrolase family

María Alcaide; Jesús Tornés; Peter J. Stogios; Xiaohui Xu; Christoph Gertler; Rosa Di Leo; Rafael Bargiela; Álvaro Lafraya; María-Eugenia Guazzaroni; Nieves López-Cortés; Tatyana N. Chernikova; Olga V. Golyshina; Taras Y. Nechitaylo; Iris Plumeier; Dietmar H. Pieper; Michail M. Yakimov; Alexei Savchenko; Peter N. Golyshin; Manuel Ferrer

Biochem J (2013) 454 (1): 157–166.

Abstract

View Articletitled, Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the α/β hydrolase family

Supplementary data

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Correction articles

Structural characterization of amorphous calcium carbonate-binding protein: an insight into the mechanism of amorphous calcium carbonate formation

J. Su; X. Liang; Q. Zhou; G. Zhang; H. Wang; L. Xie; R. Zhang

Biochem J (2013) 454 (1): 167.

Extract

View Articletitled, Structural characterization of amorphous calcium carbonate-binding protein: an insight into the mechanism of amorphous calcium carbonate formation

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Activin E is a transforming growth factor β ligand that signals specifically through activin receptor-like kinase 7

Correction: Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition

Expression of Concern: Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway

Expression of nNOS alpha and beta isoforms in skeletal muscle of mice

AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Review articles

Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes

SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions

Research articles

Vesicular uptake of N-acetylaspartylglutamate is catalysed by sialin (SLC17A5)

Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3

Trafficking defects in PAS domain mutant K_v11.1 channels: roles of reduced domain stability and altered domain–domain interactions

The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53–N-WASP interaction in epithelial cells

Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate

Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits

CD25 and CD69 induction by α4β1 outside-in signalling requires TCR early signalling complex proteins

The CPVT-associated RyR2 mutation G230C enhances store overloadinduced Ca²⁺ release and destabilizes the N-terminal domains

Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes

Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the α/β hydrolase family

Correction articles

Structural characterization of amorphous calcium carbonate-binding protein: an insight into the mechanism of amorphous calcium carbonate formation

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