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Volume 451, Issue 2

April 2013

All Issues

Cover Image

Cover Image
Front Matter
Table of Contents
Editorial Board

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Review articles
Research articles
Correction articles
Commentaries

Review articles

The cell cycle and pluripotency

Christopher Hindley; Anna Philpott

Biochem J (2013) 451 (2): 135–143.

Abstract

View Articletitled, The cell cycle and pluripotency

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Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis

Margret Sauter; Barbara Moffatt; Maye Chin Saechao; Rüdiger Hell; Markus Wirtz

Biochem J (2013) 451 (2): 145–154.

Abstract

View Articletitled, Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis

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Research articles

Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter

Ira Kukic; Jeffrey K. Lee; Jessica Coblentz; Shannon L. Kelleher; Kirill Kiselyov

Biochem J (2013) 451 (2): 155–163.

Abstract

View Articletitled, Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter

Supplementary data

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Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1

Nicholas T. Redpath; Yibin Xu; Nicholas J. Wilson; Louis J. Fabri; Manuel Baca; Arna E. Andrews; Hal Braley; Ping Lu; Cheryl Ireland; Robin E. Ernst; Andrea Woods; Gail Forrest; Zhiqiang An; Dennis M. Zaller; William R. Strohl; Cindy S. Luo; Peter E. Czabotar; Thomas P. J. Garrett; Douglas J. Hilton; Andrew D. Nash; Jian-Guo Zhang; Nicos A. Nicola

Biochem J (2013) 451 (2): 165–175.

Abstract

View Articletitled, Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1

Supplementary data

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Subtype-selective regulation of IP₃ receptors by thimerosal via cysteine residues within the IP₃-binding core and suppressor domain

Samir A. Khan; Ana M. Rossi; Andrew M. Riley; Barry V. L. Potter; Colin W. Taylor

Biochem J (2013) 451 (2): 177–184.

Abstract

View Articletitled, Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain

Supplementary data

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The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

John S. Bett; Adel F. M. Ibrahim; Amit K. Garg; Van Kelly; Patrick Pedrioli; Sonia Rocha; Ronald T. Hay

Biochem J (2013) 451 (2): 185–194.

Abstract

View Articletitled, The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

Supplementary data

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Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment

Yuko Iwakiri; Sachiko Kamakura; Junya Hayase; Hideki Sumimoto

Biochem J (2013) 451 (2): 195–204.

Abstract

View Articletitled, Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment

Supplementary data

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Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis

Anna-Lena Kaufholz; Gregory A. Hunter; Gloria C. Ferreira; Thomas Lendrihas; Vanessa Hering; Gunhild Layer; Martina Jahn; Dieter Jahn

Biochem J (2013) 451 (2): 205–216.

Abstract

View Articletitled, Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis

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Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity

Emily Golden; Rachel Paterson; Wan Jun Tie; Anandhi Anandan; Gavin Flematti; Gianluca Molla; Elena Rosini; Loredano Pollegioni; Alice Vrielink

Biochem J (2013) 451 (2): 217–226.

Abstract

View Articletitled, Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity

Supplementary data

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Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1

Su-Jin Kim; Ziliang Ao; Garth Warnock; Christopher H. S. McIntosh

Biochem J (2013) 451 (2): 227–234.

Abstract

View Articletitled, Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1

Supplementary data

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HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors

A. Gabrielle J. van der Kraan; Ryan C. C. Chai; Preetinder P. Singh; Benjamin J. Lang; Jiake Xu; Matthew T. Gillespie; John T. Price; Julian M. W. Quinn

Biochem J (2013) 451 (2): 235–244.

Abstract

View Articletitled, HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors

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V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins

Caihong Zhou; Yan Zhou; Jia Wang; Yang Feng; Haonan Wang; Jinglun Xue; Yani Chen; Richard D. Ye; Ming-Wei Wang

Biochem J (2013) 451 (2): 245–255.

Abstract

View Articletitled, V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins

Supplementary data

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Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells

Janete Chung; Antonio A. Rocha; Renata R. Tonelli; Beatriz A. Castilho; Sergio Schenkman

Biochem J (2013) 451 (2): 257–267.

Abstract

View Articletitled, Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells

Supplementary data

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Regulation of Bacillus subtilis DesK thermosensor by lipids

Mariana Martín; Diego de Mendoza

Biochem J (2013) 451 (2): 269–275.

Abstract

View Articletitled, Regulation of Bacillus subtilis DesK thermosensor by lipids

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Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example

Sarah Schlosser; David Leitsch; Michael Duchêne

Biochem J (2013) 451 (2): 277–288.

Abstract

View Articletitled, Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example

Supplementary data

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Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from Clostridium thermocellum (CtCBM11)

Aldino Viegas; João Sardinha; Filipe Freire; Daniel F. Duarte; Ana L. Carvalho; Carlos M. G. A. Fontes; Maria J. Romão; Anjos L. Macedo; Eurico J. Cabrita

Biochem J (2013) 451 (2): 289–300.

Abstract

View Articletitled, Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from Clostridium thermocellum (CtCBM11)

Supplementary data

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Prohepcidin binds to the HAMP promoter and autoregulates its own expression

Edina Pandur; Katalin Sipos; László Grama; Judit Nagy; Viktor S. Poór; György Sétáló, Jr; Attila Miseta; Zsuzsanna Fekete

Biochem J (2013) 451 (2): 301–311.

Abstract

View Articletitled, Prohepcidin binds to the HAMP promoter and autoregulates its own expression

Supplementary data

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A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery

Yinghong Gao; Stephen P. Davies; Martin Augustin; Anna Woodward; Umesh A. Patel; Robert Kovelman; Kevin J. Harvey

Biochem J (2013) 451 (2): 313–328.

Abstract

View Articletitled, A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery

Supplementary data

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Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes

Svend Kjær; Mark Linch; Andrew Purkiss; Brenda Kostelecky; Phillip P. Knowles; Carine Rosse; Philippe Riou; Christelle Soudy; Sarah Kaye; Bhavisha Patel; Erika Soriano; Judith Murray-Rust; Caroline Barton; Christian Dillon; Jon Roffey; Peter J. Parker; Neil Q. McDonald

Biochem J (2013) 451 (2): 329–342.

Abstract

View Articletitled, Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes

Supplementary data

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Correction articles

Mind the gap: cytochrome interactions reveal electron pathways across the periplasm of Shewanella oneidensis MR-1

B. M. Fonseca; C. M. Paquete; S. E. Neto; I. Pacheco; C. M. Soares; R. O. Louro

Biochem J (2013) 451 (2): 343.

Extract

View Articletitled, Mind the gap: cytochrome interactions reveal electron pathways across the periplasm of Shewanella oneidensis MR-1

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G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy

X. Ding; X. Zhao; A. Watts

Biochem J (2013) 451 (2): 343.

Extract

View Articletitled, G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy

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Identification of novel candidate phosphatidic acid-binding proteins involved in the salt-stress response of Arabidopsis thaliana roots

F. Mcloughlin; S. A. Arisz; H. L. Dekker; G. Kramer; C. G. de Koster; M. A. Haring; T. Munnik; C. Testerink

Biochem J (2013) 451 (2): 343.

Extract

View Articletitled, Identification of novel candidate phosphatidic acid-binding proteins involved in the salt-stress response of Arabidopsis thaliana roots

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Commentaries

With an antibody whose duty's double, a step towards ending asthma trouble?

Eric J. Sundberg

Biochem J (2013) 451 (2): e1–e3.

Abstract

View Articletitled, With an antibody whose duty's double, a step towards ending asthma trouble?

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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria

AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Activin E is a transforming growth factor β ligand that signals specifically through activin receptor-like kinase 7

Correction: Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition

Expression of Concern: Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway

Review articles

The cell cycle and pluripotency

Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis

Research articles

Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter

Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1

Subtype-selective regulation of IP₃ receptors by thimerosal via cysteine residues within the IP₃-binding core and suppressor domain

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment

Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis

Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity

Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1

HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors

V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins

Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells

Regulation of Bacillus subtilis DesK thermosensor by lipids

Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example

Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from Clostridium thermocellum (CtCBM11)

Prohepcidin binds to the HAMP promoter and autoregulates its own expression

A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery

Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes

Correction articles

Mind the gap: cytochrome interactions reveal electron pathways across the periplasm of Shewanella oneidensis MR-1

G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy

Identification of novel candidate phosphatidic acid-binding proteins involved in the salt-stress response of Arabidopsis thaliana roots

Commentaries

With an antibody whose duty's double, a step towards ending asthma trouble?

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