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Volume 350, Issue 1
August 2000
Issue Cover
All Issues
ISSN 0264-6021
EISSN 1470-8728
In this Issue

Review articles

Signal-dependent membrane targeting by pleckstrin homology (PH) domains
Mark A. LEMMON; Kathryn M. FERGUSON
Biochem J (2000) 350 (1): 1–18.
View Articletitled, Signal-dependent membrane targeting by pleckstrin homology (PH) domains
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Research articles

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of Gαo
Sabine TRAVER; Carole BIDOT; Nathalie SPASSKY; Tania BALTAUSS; Marie-France DE TAND; Jean-Léon THOMAS; Bernard ZALC; Isabelle JANOUEIX-LEROSEY; Jean DE GUNZBURG
Biochem J (2000) 350 (1): 19–29.
View Articletitled, RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of Gαo
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The influence of secretory-protein charge on late stages of secretion from the Gram-positive bacterium Bacillus subtilis
Keith STEPHENSON; Christina L. JENSEN; Steen T. JØRGENSEN; Jeremy H. LAKEY; Colin R. HARWOOD
Biochem J (2000) 350 (1): 31–39.
View Articletitled, The influence of secretory-protein charge on late stages of secretion from the Gram-positive bacterium Bacillus subtilis
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Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells
Lesley J. BRUCE; Oliver WRONG; Ashley M. TOYE; Mark T. YOUNG; Graham OGLE; Zulkifli ISMAIL; Ashim K. SINHA; Paddy MCMASTER; Ilomo HWAIHWANJE; Gerard B. NASH; Sarah HART; Evelyn LAVU; Ronald PALMER; Ainoon OTHMAN; Robert J. UNWIN; Michael J. A. TANNER
Biochem J (2000) 350 (1): 41–51.
View Articletitled, Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells
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Red-cell glycophorin A–band 3 interactions associated with the movement of band 3 to the cell surface
Mark T. YOUNG; Roland BECKMANN; Ashley M. TOYE; Michael J. A. TANNER
Biochem J (2000) 350 (1): 53–60.
View Articletitled, Red-cell glycophorin A–band 3 interactions associated with the movement of band 3 to the cell surface
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Malonyl-CoA metabolism in cardiac myocytes
Christian HAMILTON; E. David SAGGERSON
Biochem J (2000) 350 (1): 61–67.
View Articletitled, Malonyl-CoA metabolism in cardiac myocytes
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Mutagenesis studies on the sensitivity of Escherichia coli acetohydroxyacid synthase II to herbicides and valine
Yu-Ting LEE; Ronald G. DUGGLEBY
Biochem J (2000) 350 (1): 69–73.
View Articletitled, Mutagenesis studies on the sensitivity of Escherichia coli acetohydroxyacid synthase II to herbicides and valine
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Characterization of derivatives of the high-molecular-mass penicillin-binding protein (PBP) 1 of Mycobacterium leprae
Sebabrata MAHAPATRA; Sanjib BHAKTA; Jasimuddin AHAMED; Joyoti BASU
Biochem J (2000) 350 (1): 75–80.
View Articletitled, Characterization of derivatives of the high-molecular-mass penicillin-binding protein (PBP) 1 of Mycobacterium leprae
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Effects of modification of the hydrophobic C-1–C-16 segment of tautomycin on its affinity to type-1 and type-2A protein phosphatases
Akira TAKAI; Katsunori TSUBOI; Masayoshi KOYASU; Minoru ISOBE
Biochem J (2000) 350 (1): 81–88.
View Articletitled, Effects of modification of the hydrophobic C-1–C-16 segment of tautomycin on its affinity to type-1 and type-2A protein phosphatases
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Mutation of threonine-241 to proline eliminates autocatalytic modification of human carbonyl reductase
Michel A. SCIOTTI; Shizuo NAKAJIN; Bendicht WERMUTH; Michael E. BAKER
Biochem J (2000) 350 (1): 89–92.
View Articletitled, Mutation of threonine-241 to proline eliminates autocatalytic modification of human carbonyl reductase
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Peroxisome-proliferator-activated receptor δ mediates the effects of long-chain fatty acids on post-confluent cell proliferation
Chantal JEHL-PIETRI; Claire BASTIE; Isabelle GILLOT; Serge LUQUET; Paul A. GRIMALDI
Biochem J (2000) 350 (1): 93–98.
View Articletitled, Peroxisome-proliferator-activated receptor δ mediates the effects of long-chain fatty acids on post-confluent cell proliferation
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The cytosolic C-terminus of the glucose transporter GLUT4 contains an acidic cluster endosomal targeting motif distal to the dileucine signal
Annette M. SHEWAN; Brad J. MARSH; Derek R. MELVIN; Sally MARTIN; Gwyn W. GOULD; David E. JAMES
Biochem J (2000) 350 (1): 99–107.
View Articletitled, The cytosolic C-terminus of the glucose transporter GLUT4 contains an acidic cluster endosomal targeting motif distal to the dileucine signal
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Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration
Innoc HAN; Eok-Soo OH; Jeffrey E. KUDLOW
Biochem J (2000) 350 (1): 109–114.
View Articletitled, Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration
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cAMP attenuates interleukin-1-stimulated macrophage colony-stimulating factor (M-CSF) expression
Pisate J. KAMTHONG; Fu-mei WU; Ming-chi WU
Biochem J (2000) 350 (1): 115–122.
View Articletitled, cAMP attenuates interleukin-1-stimulated macrophage colony-stimulating factor (M-CSF) expression
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A natural sequence consisting of overlapping glucocorticoid-responsive elements mediates glucocorticoid, but not androgen, regulation of gene expression
Charbel MASSAAD; Michèle GARLATTI; Elizabeth M. WILSON; Françoise CADEPOND; Robert BAROUKI
Biochem J (2000) 350 (1): 123–129.
View Articletitled, A natural sequence consisting of overlapping glucocorticoid-responsive elements mediates glucocorticoid, but not androgen, regulation of gene expression
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Tumour necrosis factor-α and interferon-γ synergistically activate the RANTES promoter through nuclear factor κB and interferon regulatory factor 1 (IRF-1) transcription factors
Ahn Hwee LEE; Jeong-Ho HONG; Yeon-Soo SEO
Biochem J (2000) 350 (1): 131–138.
View Articletitled, Tumour necrosis factor-α and interferon-γ synergistically activate the RANTES promoter through nuclear factor κB and interferon regulatory factor 1 (IRF-1) transcription factors
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Kinetic and structural analysis of the ultrasensitive behaviour of cyanobacterial ADP-glucose pyrophosphorylase
Diego F. GÓMEZ CASATI; Miguel A. AON; Alberto A. IGLESIAS
Biochem J (2000) 350 (1): 139–147.
View Articletitled, Kinetic and structural analysis of the ultrasensitive behaviour of cyanobacterial ADP-glucose pyrophosphorylase
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Stimulation of fructose transport across the intestinal brush-border membrane by PMA is mediated by GLUT2 and dynamically regulated by protein kinase C
Philip A. HELLIWELL; Michael RICHARDSON; Julie AFFLECK; George L. KELLETT
Biochem J (2000) 350 (1): 149–154.
View Articletitled, Stimulation of fructose transport across the intestinal brush-border membrane by PMA is mediated by GLUT2 and dynamically regulated by protein kinase C
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The diffusive component of intestinal glucose absorption is mediated by the glucose-induced recruitment of GLUT2 to the brush-border membrane
George L. KELLETT; Philip A. HELLIWELL
Biochem J (2000) 350 (1): 155–162.
View Articletitled, The diffusive component of intestinal glucose absorption is mediated by the glucose-induced recruitment of GLUT2 to the brush-border membrane
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Regulation of GLUT5, GLUT2 and intestinal brush-border fructose absorption by the extracellular signal-regulated kinase, p38 mitogen-activated kinase and phosphatidylinositol 3-kinase intracellular signalling pathways: implications for adaptation to diabetes
Philip A. HELLIWELL; Michael RICHARDSON; Julie AFFLECK; George L. KELLETT
Biochem J (2000) 350 (1): 163–169.
View Articletitled, Regulation of GLUT5, GLUT2 and intestinal brush-border fructose absorption by the extracellular signal-regulated kinase, p38 mitogen-activated kinase and phosphatidylinositol 3-kinase intracellular signalling pathways: implications for adaptation to diabetes
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Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells
Gemma ENRIQUE-TARANCÓN; Isabelle CASTAN; Nathalie MORIN; Luc MARTI; Anna ABELLA; Marta CAMPS; Roser CASAMITJANA; Manuel PALACÍN; Xavier TESTAR; Eva DEGERMAN; Christian CARPÉNÉ; Antonio ZORZANO
Biochem J (2000) 350 (1): 171–180.
View Articletitled, Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells
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Catabolism of aggrecan, decorin and biglycan in tendon
Sarah G. REES; Carl R. FLANNERY; Chris B. LITTLE; Clare E. HUGHES; Bruce CATERSON; Colin M. DENT
Biochem J (2000) 350 (1): 181–188.
View Articletitled, Catabolism of aggrecan, decorin and biglycan in tendon
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Identification of domains responsible for signal recognition and transduction within the QUTR transcription repressor protein
Lisa J. LEVETT; Shi Ming SI-HOE; Stuart LIDDLE; Kerry WHEELER; Deborah SMITH; Heather K. LAMB; Giles H. NEWTON; John R. COGGINS; Alastair R. HAWKINS
Biochem J (2000) 350 (1): 189–197.
View Articletitled, Identification of domains responsible for signal recognition and transduction within the QUTR transcription repressor protein
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Cloning and characterization of a novel human histone deacetylase, HDAC8
Joseph J. BUGGY; Mindy L. SIDERIS; Polly MAK; Donald D. LORIMER; Brian MCINTOSH; James M. CLARK
Biochem J (2000) 350 (1): 199–205.
View Articletitled, Cloning and characterization of a novel human histone deacetylase, HDAC8
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Phosphoinositide 3-kinase-dependent Ras activation by tauroursodesoxycholate in rat liver
Anna Kordelia KURZ; Christoph BLOCK; Dirk GRAF; Stephan VOM DAHL; Freimut SCHLIESS; Dieter HÄUSSINGER
Biochem J (2000) 350 (1): 207–213.
View Articletitled, Phosphoinositide 3-kinase-dependent Ras activation by tauroursodesoxycholate in rat liver
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Peroxidation of proteins before lipids in U937 cells exposed to peroxyl radicals
Steven GIESEG; Sean DUGGAN; Janusz M. GEBICKI
Biochem J (2000) 350 (1): 215–218.
View Articletitled, Peroxidation of proteins before lipids in U937 cells exposed to peroxyl radicals
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The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
Kai-Stefan DIMMER; Björn FRIEDRICH; Florian LANG; Joachim W. DEITMER; Stefan BRÖER
Biochem J (2000) 350 (1): 219–227.
View Articletitled, The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
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Identification of amino acid residues important in the cyclization reactions of chalcone and stilbene synthases
Dae-Yeon SUH; Kazuki FUKUMA; Junichi KAGAMI; Yasuyo YAMAZAKI; Masaaki SHIBUYA; Yutaka EBIZUKA; Ushio SANKAWA
Biochem J (2000) 350 (1): 229–235.
View Articletitled, Identification of amino acid residues important in the cyclization reactions of chalcone and stilbene synthases
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Kinetics of a self-amplifying substrate cycle: ADP–ATP cycling assay
Edelmira VALERO; Ramón VARÓN; Francisco GARCÍA-CARMONA
Biochem J (2000) 350 (1): 237–243.
View Articletitled, Kinetics of a self-amplifying substrate cycle: ADP–ATP cycling assay
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Effect of heparin and liver heparan sulphate on interaction of HepG2-derived transcription factors and their cis-acting elements: altered potential of hepatocellular carcinoma heparan sulphate
József DUDÁS; Giuliano RAMADORI; Thomas KNITTEL; Katrin NEUBAUER; Dirk RADDATZ; Krisztina EGEDY; Ilona KOVALSZKY
Biochem J (2000) 350 (1): 245–251.
View Articletitled, Effect of heparin and liver heparan sulphate on interaction of HepG2-derived transcription factors and their cis-acting elements: altered potential of hepatocellular carcinoma heparan sulphate
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Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription
Raman P. NAGARAJAN; Yan CHEN
Biochem J (2000) 350 (1): 253–259.
View Articletitled, Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription
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Expression of Escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis
Beatriz M. BONINI; Christophe VAN VAECK; Christer LARSSON; Lena GUSTAFSSON; Pingsheng MA; Joris WINDERICKX; Patrick VAN DIJCK; Johan M. THEVELEIN
Biochem J (2000) 350 (1): 261–268.
View Articletitled, Expression of Escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis
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Fine mapping of the α-actinin binding site within cysteine-rich protein
Brooke D. HARPER; Mary C. BECKERLE; Pascal POMIÈS
Biochem J (2000) 350 (1): 269–274.
View Articletitled, Fine mapping of the α-actinin binding site within cysteine-rich protein
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Membrane pore architecture of a cytolytic toxin from Bacillus thuringiensis
Boonhiang PROMDONKOY; David J. ELLAR
Biochem J (2000) 350 (1): 275–282.
View Articletitled, Membrane pore architecture of a cytolytic toxin from Bacillus thuringiensis
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Interaction of the collagen-like tail of asymmetric acetylcholinesterase with heparin depends on triple-helical conformation, sequence and stability
Paola DEPREZ; Ellen DOSS-PEPE; Barbara BRODSKY; Nibaldo C. INESTROSA
Biochem J (2000) 350 (1): 283–290.
View Articletitled, Interaction of the collagen-like tail of asymmetric acetylcholinesterase with heparin depends on triple-helical conformation, sequence and stability
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Thrombospondin 1 does not activate transforming growth factor β1 in a chemically defined system or in smooth-muscle-cell cultures
David J. GRAINGER; Emma K. FROW
Biochem J (2000) 350 (1): 291–298.
View Articletitled, Thrombospondin 1 does not activate transforming growth factor β1 in a chemically defined system or in smooth-muscle-cell cultures
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Differential regulation of Ca2+/calmodulin-dependent enzymes by plant calmodulin isoforms and free Ca2+ concentration
Sang Hyoung LEE; J. David JOHNSON; Michael P. WALSH; Jacquelyn E. VAN LIEROP; Cindy SUTHERLAND; Ande XU; Wayne A. SNEDDEN; Danuta KOSK-KOSICKA; Hillel FROMM; Njanoor NARAYANAN; Moo Je CHO
Biochem J (2000) 350 (1): 299–306.
View Articletitled, Differential regulation of Ca2+/calmodulin-dependent enzymes by plant calmodulin isoforms and free Ca2+ concentration
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Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts
Ruth D. THORNTON; Pamela LANE; Ruth C. BORGHAEI; Elizabeth A. PEASE; Jaime CARO; Eugene MOCHAN
Biochem J (2000) 350 (1): 307–312.
View Articletitled, Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts
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Oxygen and haem regulate the synthesis of peroxisomal proteins: catalase A, acyl-CoA oxidase and Pex1p in the yeast Saccharomyces cerevisiae; the regulation of these proteins by oxygen is not mediated by haem
Marek SKONECZNY; Joanna RYTKA
Biochem J (2000) 350 (1): 313–319.
View Articletitled, Oxygen and haem regulate the synthesis of peroxisomal proteins: catalase A, acyl-CoA oxidase and Pex1p in the yeast Saccharomyces cerevisiae; the regulation of these proteins by oxygen is not mediated by haem
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Purification and characterization of Ak.1 protease, a thermostable subtilisin with a disulphide bond in the substrate-binding cleft
Helen S. TOOGOOD; Clyde A. SMITH; Edward N. BAKER; Roy M. DANIEL
Biochem J (2000) 350 (1): 321–328.
View Articletitled, Purification and characterization of Ak.1 protease, a thermostable subtilisin with a disulphide bond in the substrate-binding cleft
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The analysis of intermolecular interactions in concentrated hyaluronan solutions suggest no evidence for chain–chain association
Phillip GRIBBON; Boon Chin HENG; Timothy E. HARDINGHAM
Biochem J (2000) 350 (1): 329–335.
View Articletitled, The analysis of intermolecular interactions in concentrated hyaluronan solutions suggest no evidence for chain–chain association
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